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10 Cards in this Set
- Front
- Back
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During a migraine attack, what happens to 5-HT levels in the blood and urine?
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bld levels dec, urine levels inc
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What happens to dorsal raphe nerve cells during sleep?
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they dec firing
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Which receptors are responsible for SMC relaxation, contraction of some vascular SMC?
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5-HT1A,1B,1D
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Which receptors are responsible for vasoconstriction of most blood vessles, bronchoconstriction, contraction of GI SMC, platelet aggregation?
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5-HT2
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What happens when 5HT1D are stimulated?
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neuronal inhibition of CNS
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What happens when 5-HT1B are stimulated?
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relaxation
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Where are 5-HT1 receptors located?
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cephalic vessels
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Which drugs are therapeutic for migraine?
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5-HT1 selective drugs
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What are the contraindications for lithium?
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nephrogenic diabetes insipidus, thyroid disease, tremor
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What are the contraindications for propanolol?
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asthma, COPD, heart dx, bradycardia, DMII
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