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5 Cards in this Set

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changes in androgens during menopause
-decr delta-4 (ovarian production) by 50%
-decr DHEA-S (adrenal production) by 30%
-although both estrogens and androgenes decrease, women become more androgenic b/c big decrease in estradiol but only slight decr in test
-ovaries produce lots of testosterone, so women who had ovarectomies have much less testost than other post-menopausal women
hallmark of low estrogen
1. acute sensation of heat ("flash")
2. skin changes w/sweating ("flush"=red)
-flushing occurs in first 2 years of menopause, can last up to 10 yrs

*only 10% find the Sx disabling
gold std for assessing bone mass
Dual Energy X-Ray Absorptiometry (DEXA):

-Z score for DEXA compares your bone mass to your age group
-T score of DEXA compares you to 35 y/o woman
*use T score to define osteoporosis
*nl < 2.5 SD's below mean bone mass of 35 y/o woman
how define osteoporosis
*use T score to define osteoporosis
-T score of DEXA compares you to 35 y/o woman
*nl < 2.5 SD's below mean bone mass of 35 y/o woman
when Tx post-menopausal woman with supplemental estrogen or HRT?
The only indication for Tx with supplemental estrogen or HRT is if pt is SYMPTOMATIC
(Sx=vasomotor, urinary, vaginal)