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5 Cards in this Set
- Front
- Back
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changes in androgens during menopause
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-decr delta-4 (ovarian production) by 50%
-decr DHEA-S (adrenal production) by 30% -although both estrogens and androgenes decrease, women become more androgenic b/c big decrease in estradiol but only slight decr in test -ovaries produce lots of testosterone, so women who had ovarectomies have much less testost than other post-menopausal women |
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hallmark of low estrogen
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1. acute sensation of heat ("flash")
2. skin changes w/sweating ("flush"=red) -flushing occurs in first 2 years of menopause, can last up to 10 yrs *only 10% find the Sx disabling |
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gold std for assessing bone mass
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Dual Energy X-Ray Absorptiometry (DEXA):
-Z score for DEXA compares your bone mass to your age group -T score of DEXA compares you to 35 y/o woman *use T score to define osteoporosis *nl < 2.5 SD's below mean bone mass of 35 y/o woman |
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how define osteoporosis
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*use T score to define osteoporosis
-T score of DEXA compares you to 35 y/o woman *nl < 2.5 SD's below mean bone mass of 35 y/o woman |
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when Tx post-menopausal woman with supplemental estrogen or HRT?
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The only indication for Tx with supplemental estrogen or HRT is if pt is SYMPTOMATIC
(Sx=vasomotor, urinary, vaginal) |
