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162 Cards in this Set

  • Front
  • Back
Normal GFR
125ml/min
Where 80% of electrolytes are reabsorbed
Proximal Convoluted Tubule
Hormone required for water reabsoption in the kidney; also very important for water balance
Antidiuretic Hormone (ADH)
Normal adult urine output per day
1500ml/24hrs
An abnormal murmur or "swooshing sound" heard over the abdominal aorta and renal arteries.
Bruit
The bladder is not percusable until it contains ml of urine.
150
A waste product of protein breakdown.
Creatinine
Diagnostic test used to approximate to GFR.
24hr Creatinine Clearance
Evaluates renal concentration ability.
Normal finding: 1.020-1.035
Concentration test
Normal BUN
10-30
Normal Creatinine
0.5-1.5mg/dl
Normal BUN/Creat ratio
10/20:1
Diagnostic test also known as a "flat plate".
KUB
an x-ray that visualizes the urinary tract after IV injection of contrast material.
Intravenous Pyelogram (IVP)
Prep required for IVP
NPO x 8hrs, Cathartic or enema (fleets) for bowel prep, Assess for contrast allergy!!, Caution with renal patients!! (contrast)
Diagnostic test used to visualize renal blood vessels. Used to rule out Renal Artery Stenosis
Renal Arteriogram
Prep required for Renal Arteriogram
Assess iodine sensitvity, Give Cathartic or enema evening prior to exam.
Post-procedure nursing assessment for Renal Arteriogram
Apply pressure dressing over femoral artery injection site, Pt to remain bedrest with affected leg straight,
Assess peripheral pulses in affected leg Q 30-60min.
Diagnostic test used to inspect the interior of the bladder with a tubular lighted scope.
Cystoscopy
Prep required for Cystoscopy
Ensure consent form is signed, If general anesthesia is to be used, force fluids or give via IV.
Radiology procedure using contrast medium via catheter/cystoscope to assess bladder injury and vesicoureteral reflux.
Voiding Cystourethrogram
Diagnostic test used to evaluate bladder tone, sensations of filling, and bladder stability.
Cystometrogram
Diagnostic test done to obtain renal tissue for examination to determine type of/or follow renal disease.
Renal Biopsy
Post-biopsy nursing care
Apply pressure dressing, keep on affected side 30-60min, bed rest x 24hrs, assess VS Q5-10min for first hour, assess site for bleeding, flank pain, and serial urine specimens.
Infections that occur in a otherwise normal urinary tract and usually only involves the bladder.
Uncomplicated UTI
infections that include a coexisting presence of obstruction, stones, or catheters. Pt is at risk for pyelonephritis, urosepsis, and renal damage.
Complicated UTI
Uncomplicated UTI in a person who has never had an infection or experiences one that is remote from any previous UTI.
Initial Infection
Reinfection caused by a second pathogen in a person who experienced a previous infection that was successfully eradicated.
Recurrent UTI
Risk factors for UTI's
Poor Hygiene, Retention, calculi, Reflex, Catheterization, Short Urethra (females), DM, Pregnancy, Neurogenic Bladder, Enlarged Prostate,
Aging, MS
Lower Urinary Tract Infection Symptoms
Dysuria, Frequency, Urgency, Suprapubic discomfort, Hematuria, Cloudy appearing urine
Upper Urinary Tract Infection
Symptoms
Flank Pain, Chills, Fever
S/S of UTI in older adults
Nonlocalized abdominal discomfort
Cognitive impairment
Increased incontinence
Diagnostic studies done to detect UTI's
Dipstick UA
Urine Culture
Preffered way to collect a urine culture
Midstream void, clean catch
Treatment for Uncomplicated Cystitis
Short term antibiotics x 1-3 days

Meds include: TMP/SMX bid or Macrodantin tid-qid
Treatment for Complicated Cystitis
Long term antibiotic treatment lasting 7-14 days or longer

Meds include: Cipro, Levaquin, Noroxin, Floxin, and Tequin
Advise patients to wear protective clothing, avoid sunlight, and wear suncreen while taking this medication
nitrofurantoin (Macrodantin/Macrobid/
Furadantin)
The use of this OTC med may turn the urine a reddish orange color
Pyridium
Long term use of this med may cause hemolytic anemia
Pyridium
Advise patients that when taking this med, it may turn the urine blue or green
Urised
People at high risk for UTI
Debilitated persons, older adults, HIV, DM, cancer, pt's treated with immunosuppressives or corticosteroids
Preventative measures to teach UTI patients
Emptying the bladder regularly
and completely, Evacuating the bowel regularly, Wiping the perineal area from front to back after urination and defecation, Drinking an adequate amount of liquid each day
The recommended daily liquid intake for the ambulatory adult
15ml per pound of body weight
Diagnosis criteria for Interstitial Cystitis
Pain during bladder filling that is relieved by voiding, Bothersome urinary frequency and urgency, Small bladder capacity on urodynamic testing, Cystoscopic evidence of ulcerations or glomerulations, Have at lease 1 negative urine culture during period of active symptoms.
Treatments used for non-infectious cystitis
BCG, TCA antideppressents (Elavil, Aventyl), Bladder instillations of Heparin, DMSO, or Hyaluronic acid
Nurse teaching for patients with Cystitis
Take sitz bath, Maintain a generous fluid intake, Avoid Caffeine, Alcohol, coffee, tea, Acidify urine, Empty the bladder Q3-4 hrs, Do not use high potency vitamins.
S/S for Acute Pyelonephritis
Fever, chills, flank pain, CVA tenderness, malaise, signs of UTI (may or may not be present), GI s/s.
S/S for Chronic Pyelonephritis
Intermittent low grade fever and non-specific flank or abdominal pain.
Urinalysis results for acute pyelonephritis
Pyuria, Bacteriuria, Hematuria
WBC casts, CBC will show elevated Leukocytosis
Treatment for acute pyelonephritis
14-21 days of antibiotics

meds used: Rocephin and ampicillin
Caused by Mycobacterium tuberculosis, usually occurs 5-8years after primary infection
Renal Tb
S/S of Renal Tb
c/o fatigue, low grade fever, cystitis, frequent urination, burning on voiding, epididymitis, Renal colic, lumbar/iliac pain, hematuria
Diagnostic testing for Renal Tb
Pulmonary Tb screening, 3 clean-catch first urine specimens for AFB
Treatment for Renal Tb
Anti-Tb meds x 24mths
Glomerulonephritis
Inflammation of glomerulus d/t immunologic processes (accumulation of antigen, Ab, and complement).
S/S of Glomerulonephritis
Hematuria (microscopic to gross), Excretion of formed elements (WBC, RBC, casts), Protenuria, Elevated BUN/serum creatinine
Most common form of Acute Glomuerulonephritis
Post-streptococcal glomerulonephritis (APSGN)
Manifestations of APSGN
Abrupt onset of hematuria, protenuria, and edema (periorbital), cola/coffee/cocoa colored urine, fatigue, N/V, anorexia.
Nursing Interventions for APSGN
Encourage rest until HTN and glomerular inflammation subsides, Restrict sodium and fluid intake, Administer diuretics (Loop or Diazide) and antihypertensives, If BUN is elevated, restrict dietary protein.
Diagnostic testing used for APSGN
H&P, U/A, CBC w/ Diff, BUN, Creatinine and albumin, Complement levels and ASO titer, Renal biopsy (if needed).
Rapidly progressive glomerulonephritis (RPGN)
Glomerular disease associated with acute renal failure where there is rapid, progressive loss of renal function over days to weeks (FATAL!!)
Manifestations of RPGN
Hypertension, Edema, Protenuria, Hematuria, RBC casts
Treatment RPGN
Plasmapharesis, coritcosteroids, cytoxic agents, dialysis, and transplantations
Primary cause of end stage renal disease
Chronic Glomerulonephritis
Seen in patients with SLE
Lupus Nephritis
An idiosyncratic reaction to drugs and chemicals
Chemical Induced Nephritis
Common manifestations of Lupus Nephritis and Chemical Induced Nephritis
Proteinuria and Hematuria
Not a specific disorder but a group of clinical s/s associated with disease conditions
Nephrotic Syndrome
S/S of Nephrotic Syndrome
Massive Proteinuria (frothy urine), Proteinuria (>3.5g/day), Hypoalbuminemia,
Hyperlipidemia (elev Trig), Edema (measure daily wts and abd girth!)
A rare autoimmune disease where both kidneys and lungs are involved; affects primarily male smokers
Goodpasture's syndrome
S/S of Goodpasture's Syndrome
Hemoptysis, cough, crackles, rhonchi, hematuria and s/s of renal failure.
Treatment for Glomerulonephritis
Antibiotics, Immunosuppressents including steroids, ACE inhibitors and diuretics, Antilipemics (Mevacor, Colestid).
Dilation of the kidney with urine
Hydronephrosis
Dilation of the ureter with urine
Hydroureter
Hypercoagulability and thromboembolism are serious complications of this:
Nephrotic Syndrome
S/S of hydronephrosis/ureter
PAIN!! may also have increased BUN/Creat.
Emergency situation caused by obstruction or deficient strength of the bladder to contract
Urinary Retention
Treatment of urinary retention
Behavior therapy.
Catheterization and treat the cause.
Urecholine (cholinergic!) and alpha andrenergic blockers (Cardura, Hytrin, Flomax).
Avoid anticholinergic meds!!!
Risk factors for urinary calculi
Increased urine concentration, dehydration/warm climate, sedentary lifestyle, urine stasis, diet, genetic acidity/alkalinity of urine.
Manifestations of urinary calculi
PAIN!! (back/abd/flank), UTI/GI symptoms (anorexia, N/V), Hematuria, Renal colic
Cool, moist skin, Lateral flank pain down to testicles, labia, or groin.
Diagnostic testing for urinary calculi
U/A and C&S, KUB, IVP, U/S, CT, Cystoscopy, Serum calcium, phosphorus, uric acid, 24hr urine for calcium/phosph, uric acid or oxalate excretion, Stone analysis
Therapeutic measures for calcium oxalate stones
Increase hydration, Reduce dietary calcium and oxalate, Give thiazide diuretics, Give Potassium Citrate to alkalinize the urine, Give Chlestyramine to bind oxalate, Reduce daily Na+ intake
Therapeutic measures for calcium phospate stones
Low calcium, low phosphate diet, Treat underlying causes
Therapeutic measures for uric acid stones
Low purine diet,Alkanalize urine with food and Potassium Citrate, Give anti-gout drugs (allopurinol), Reduce dietary purines.
Therapeutic measures for struvite stones
Give antimicrobials or Lithostat, Acidify urine (with Vit C, ASA, cranberry, plum, protein)
Therapeutic measures for cystine stones
Alkanalize urine with potassium citrate, Give alpha-penicillamine
Complications of Lithotripsy
Hemorrhage, sepsis, abcess formation
Recommended daily urinary output to prevent stone recurrence
2L/day
Most malignant form of bladder cancer
Transitional Cell Carcinoma
Risk factors: Bladder Cancer
Cigarette smoking, Exposure to dyes in rubber/cable industries, Chronic abuse of phenectin containing analgesics, Women treated for cervical cancer with radiation, Pt's receiving Cytoxan
Risk factors: Squamous Cell Carcinoma of the bladder
Recurrent renal calculi, Chronic lower UTI
S/S of Bladder Cancer
Microscopic or gross, painless hematuria, Bladder irritability, Dysuria, Frequency, Urgency.
Diagnostic testing: Bladder Cancer
Bladder tumor antigens (u/a), IVP, u/s, CT, MRI, Cystoscopy (most reliable test)
Treatment: Bladder Cancer
BCG, Chemo, Radiation, Partial/radical cystectomy w/ urinary diversion for invasive tumor w/o mets
BCG side effects
flu-like symptoms, increased frequency, hematuria, systemic infection
This type of urinary diversion requires an external appliance for collection
Incontinent urinary diversion
This type of urinary diversion is catheterizable
Continent urinary diversion (Koch/Indiana/Florida pouch)
Preop nursing intervention: urinary diversion
Bowel prep (neomycin enema to sterilize the bowel), Teach to self cath Q6 hours and irrigate pouch daily, Stoma care
Post op care: urinary diversion
Pt will be NPO with NGT for a few days, Encourage high fluid intake to flush the diversions (after NPO status), Keep urine acidic to prevent alkaline crustations, Fit for permanent appliance 7-10 days after surgery, again at 4 wks, Monitor I&O, Stoma care, Encourage pt's to void q 2-4hrs, sit while voiding, and practice pelvic floor muscle relaxation.
Most common type of kidney cancer
Renal cell carcinoma (adenocarcinoma)
What is the most significant risk factor for kidney cancer?
Cigarette smoking
Risk factors: kidney cancer
Smoking!!, Obesity, HTN, Exposure to asbestos, gasoline, or cadmium, Male 55 and over, Renal calculi
S/S of Kidney Cancer
Hematuria, Flank pain, Paplable mass in the flank or abdomen, Wt loss, Fever, HTN, Anemia
Diagnostic testing: Kidney cancer
IVP w/ tomo, Ultrasound, Angiography, CT, MRI, Percutaneous needle aspiration
What is the treatment of choice for kidney cancer?
Radical nephrectomy with regional lymph node resection
Nursing care after nephrectomy
Pain control, TCDB to prevent atelectasis, I&O q 1-2 hrs, Daily weight, Encourage early ambulation, Monitor for adrenal insufficiency (hypoglycemia or Na+/H2O retention)
This type of neurogenic bladder has upper motor neuron dysfunction, and causes incontinence with unpredictable or incomplete voiding
Reflexic
This type of neurogenic has lower motor neuron dysfunction, pt will have no control over micturation and may experience overflow incontinence or bladder distention.
Areflexic
What is the most common complication of neurogenic bladder?
Infection d/t stasis and catheterization
What medication is used to stimulate bladder contraction?
Urecholine
What medication is used to relax the bladder and contract internal sphincter?
Probanthine
What is the most common recommended treatment for neurogenic bladder management?
Intermittent catheterizaton
What type of patients should NOT be taught the Crede or Valsalva maneuvers?
Those with spinal cord injury d/t risk of autonomic dysreflexia
This type of incontinence if charecterized by an increase in intrabdominal pressure that cauese an involuntary passage of urine.
Stress incontinence
This type of incontinence is characterized by a strong uncontrollable urge to void.
Urge incontinence
This type of incontinence occurs when the pressure of urine in overfull bladder overcomes the sphincter control; characterized by frequent loss of small amounts of urine.
Overflow incontinence
This type of incontinence is characterized by a loss of urine resulting from cognitive, funtional, or enviromental factors.
Functional incontinence
What tests are used to diagnose urinary incontinence?
PVR, Urodynamics, Ua and C&S, Cystoscopy
What is the treatment of stress incontinence?
Pelvic floor muscle exercises (kegel)/Vaginal cones, Topical estrogen creams, Weight loss if obese.
What is the treatment of urge incontinece?
Bladder retraining, Anticholinergic meds/CCB's, Vaginal estrogen creams, Pelvic floor muscle exercises
What is the treatment for overflow incontinence?
Urinary catheterization to decompress the bladder, Crede's or Valsalva maneuver, Alpha-andrenergic blockers, 5alpha-reductase inhibitors, Urecholine, Intermittent catheterization, Intravaginal devices (pessary).
What is the treatment for functional incontinence?
Environment modifications: easy toilet access, better lighting, ambulatory assistance/devices, clothing alterations, timed voiding.
What type of meds increase the resistance of urethra/bladder outlet or suppress bladder contraction? For what type of incontinence?
Anticholinergic.

For stress or urge incontinence.
What type of meds increase bladder pressure/contraction and decrease outlet resistance? For what type of incontinence?
Cholinergic meds

For overflow incontinence
What medications are considered alpha-andrenergic blockers?
Cardura, Hytrin, Flomax, Uroxatrol
What medication is considered an alpha5 reductase inhibitor?
Proscar
What medications are considered anticholinergic?
Diropan, Sanctura, Oxytrol, Detrol, Enablex, Vesicare, Tofranil.
What are the signs of kidney/bladder/or urethra trauma?
Hematuria, increased abdominal pain, no urine output.
What tests are used to diagnose renal trauma?
KUB, Cystogram, IVP, Renal angiogram, CT, MRI
If blood is seen on the urethra, this indicates what?
Trauma!! Do NOT insert a foley if noted
Treatment: Renal Trauma
Bed rest, Fluids, Analgesia, Surgical exploration/repair
Nursing Interventions: Renal Trauma
Monitor VS, Monitor I&O, Assess s/s of shock, Ensure increased fluid intake, Observe for hematuria, Observe for myoglobinuria, Assess cardiovascular status,
Monitor nephrotoxic abx
A renal artery tear can put a patient at risk for what?
Vascular collapse
What is the best diagnostic tool used to identify renal artery stenois?
Renal arteriogram
How is renal artery stenosis and nephrosclerosis treated?
With antihypertensive meds
Malignant nephrosclerosis is characterized by what?
a sharp increase in BP with a diastolic pressure greater than 130mmHg
What are the s/s of renal vein thrombosis?
Flank pain, Hematuria, Fever, May have nephrotic syndrome
How is renal vein thrombosis treated?
With anticoagulant therapy (heparin, coumdadin).

*surigical thrombectomy may be performed along with anticoagulation.
What are the s/s of Polycystic Kidney Disease?
Flank/abd pain, HTN, Hematuria
Proteinuria, Nocturia, Polyuria, Signs of infection
Constipation, Severe headache (Berry aneurysm)
How is PKD diagnosed?
Ultrasound and renal function tests, CT, Family history
How is PKD treated?
Prevent infections of the urinary tract.

*Kidney transplant is the only cure
What are the HIV related renal syndromes?
Proteinuria and Nephrotic syndrome.
HIV-associated nephropathy.
Acute renal failure.
Factors that reduce renal blood flow and lead to decreased glomerular perfusion and filtration are known as:
Prerenal
Causes of prerenal ARF
Volume depletion(Hemorrhage, diuretics, GI loss), Impaired cardiac insufficiency MI, CHF, Dyrhythmias), Vasodilation (sepsis, anaphylaxis, anti-HTN meds).
This type of ARF is a result of direct parenchymal damage
Intrarenal
Causes of Intrarenal ARF
Prolonged ischemia (surgery, severe hypovolemia, sepsis, trauma, burns), Nephrotoxins (antibiotics, NSAIDS, contrast), Myoglobin (muscle trauma, infection), Hemoglobin (transfusion reactions) *released from hemolyzed RBC
This type of ARF is caused as a result of an obstruction of urine flow.
Postrenal
Causes of Postrenal ARF
Prostate cancer, Urinary calculi, BPH, Extrarenal tumors
The most common initial manifestation of ARF is:
Oliguria caused by a reduction in the GFR
Characteristics of Oliguric phase
Salt/Water retention (wt gain), Metabolic Acidosis,
Hyperkalemia
Characteristics of Diuretic phase
Increased urinary output, Lowered Na+ and K+, BUN/Creat should begin to lower, Dehydration, Decreased BP

* pt is at r/f hyponatremia, hypokalemia, and hypochloremia
Characteristics of Recovery phase
Begins when the GFR increases
BUN/Creat will be stable

*may take up to 12mths to stabilize
Why does acidosis occur in ARF?
Because the kidney cannot synthesize ammonia
How is ARF diagnosed?
UA, Renal ultrasound, Renal scan, CT, MRI, Renal biopsy
How is ARF managed?
Diuretics (loop diuretic-Lasix or osmotic diuretic-Mannitol), Hemodyalsis
CCRT, Fluid, Na+ restriction, Adequate calories, Rest
How can hyperkalemia be treated?
Kayexalate, Insulin IV(regular), Sodium Bicarb, Calcium Gluconate IV, Dialysis, Dietary restriction (limit to 40 mEq)
What type of renal disease is fatal without dialysis or a kidney transplant?
Chronic Kidney Disease
How is fluid restriction calculated?
Add all losses for the previous 24hrs + 600ml(insensible loss)
What is the leading cause of death in ARF?
Infection
How is renal insufficiency characterized?
GFR 20-50% of normal (<60ml/min x 3mths or longer), Azotemia with oliguria & edema
How is End Stage Renal Disease (ESRD) characterized?
GFR <5% of normal or below 15ml/min, Uremia
Clinical Manifestions of ESRD:

Cardiovascular-
Hematologic-
GI-
Neurologic-
Musculoskeletal-
Endocrine-
Integumentary-
Immune-
-HTN, -Epistaxis, Low RBC, Unable to produce EPO, Anemia, -Anorexia, N/V, Uremic Fetor, -Fatigue, H/A, confusion, lethargy, -Weakness, cramping, -Hypothyroidism, Low T3 &T4, -Yellow, pale, gray, itchy skin, increased bruising, -Increased r/f infection d/t low WBC