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21 Cards in this Set
- Front
- Back
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cystits
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Target E. Coli
3 days: TMP/SMX, FQ 7 days: B-lactams, Nitrofurantoin |
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Fosfomycin
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inhibits enolpyruvate transferase
(EPTF catalyzes final step in cell wall synth) Many urinary gram negative RENALLY ELIMINATED ONE TIME DOSE |
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Community Acq Pyelonephritis: oral
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E. Coli and other gram negs
Oral: FQ 3rd gen ceph Nitrofurantoin not appropriate: DOSEN'T STAY IN TISSUE 7-10 days for uncompl 14 days for majority |
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Comm Acq Pyelonephritis: IV
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FQ
Aminoglycosides 3rd gen ceph --Target therapy against isolated pathogens |
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Asymptomatic bacteriuria
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Major cause of innapp. abx use
Only treat if: preg, neonate, renal transplant, urinary tract surgery |
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Candiduria
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Represents colonization, not active infection
Discontinue Foley D/C uncess abx |
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Chancroid
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Azithromycin 1 g PO x 1 dose
Ceftriaxone IM Cipro 500 mg BID x 3 days topical erythromycin TID x 7 days Treat sex partners |
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HSV- Genital
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Acyclovir x 7-10 days
Alt: valacyclovir or famciclovir |
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Recurrent Genital Herpes
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Valacyclovir once daily
or acyclovir/famicilovir twice daily |
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Genital herpes- severe
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IV acyclovir 2-7 days, oral therapy to complete
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Syphilis, primary, secondary, tert, latent
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Penicillin
primary/secondary: IM benzathine x 1 latent: IM benzathine 1 x weeks/3weeks tert: same 3 dose neurosyph: Crystalline penicillin 10-14 days |
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Jarisch-Herxheimer RXN
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Somes after Tx for syph
Headache, myalgias, fever, tachycardia (release from pyrogen in organism) Tx: anti-inflammatory & wait |
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Chlamydia trichomaris
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Azithromycin 1 g PO x 1 dose
Doxy 100 mg po x 7 days Sex partners should be referred & abstain for 7 days |
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Neisseria gonorrhea
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Uncomplicated: IM Ceftriaxone or cefixime (alt; inferior)
NOT FQ's--- resistance likes to travel: other -itis *************ALWAYS TREAT FOR CHLAMYDIA EVEN IF CHL. NEG******* |
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Vaginosis: bacterial
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Metronidazole x 7 days
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Vaginosis: fungal
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Fluconazole x 1 dose
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Trichomonas Vaginalis
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Metro or tinidazole
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Pelvic Inflammatory Disease
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N. gonorrhea, C. trachomatis, some gram negs, anaerobes, maybe strep
Empiric Recomm: IV cefotetan/cefoxitin & doxy, clinda + genta ALT: FQ + metra, amp/sulbactam + doxy |
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Eididymitis
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C. Trachomatis, N. gonorrhea
Tx: ceftriaxone + doxy If enteric org: FQ if both a concern: ceftriaxone + FQ |
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Health-case Ass UTI
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Cover for gram negatives, resistanct pathogens: P. AERUGINOSA
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Chlamydia or Neisseria?
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Take care of sex partners as well!!!!!
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