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18 Cards in this Set

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  • Back

Where are germs cells found for spermatogenesis?

Basement membrane


Go through 3 types of division: mitosis, meiosis 1, meiosis 2


In the end, one cell gets left behind you and get 4 functional sperm cells


Spermatogenesis occurs from birth to death

When does meiosis 1 start in oogenesis?

Meiosis one occurs before birth


Nothing happens in childhood other than degradation of eggs


At puberty, a few eggs start dividing to form 2 cells.


One cell becomes a polar body


The other goes to an ovum


Meiosis 2 occurs with fertilization

Where does fertilization occur?

Occurs in outer 1/3 of uterine tube (Oviduct, fallopian tube)


Across me enzymes digest what part of the egg?

Zone pellucida, and corona radiata (aka cumulus cells)

What happens when one sperm enters ovum?

Block to polyspermy


And the sperm releases its DNA into ovum

Cleavage

When zygote immediately begins to divide upon fertilization (mitosis)

When does implantation occur?

<10 days



The store of nutrients in the ovum keeps it viable until implantation

Morola

A solid clump/mass of cells which takes about 3 days to form.



Occurs after the zygote

Blastocyst

hollow ball of cells that has formed by the time it reaches the uterus. Is after the morola. Contains the:



Tropoblast- outer cell layer, forms fetal part of placenta. Contains chorionic villi (finger like projections in placenta)


Inner cell mass- forms the embryo, yolk sac (non nutritive) , and amniotic cavity (fluid filled shock absorbing sac) .


Blastocele


Placenta

Has important endocrine functions:



Secretes large amounts of HCG which stimulates the corpus luteum to continue its secretion of estrogen and progesterone



HCG is the basis of a pregnancy test.

Stem cell types

Totipotency- from fertilized egg. Differentiates into ANY kind of stem cell in zygote


Pluripotency- what ^ divides into. Found in embryonic germ cells. Produce a broad range of cell types


Multipotency - adult stem cell found in some tissues, can produce a few cell types. Has three layers: ectoderm, endoderm , mesoderm


Unipotency - somatic cells. Keep generating just that type of cell


Formation if primary germ layers (histogenesis)

Each germ layer arise in 1st trimester and give rise to specific organs and tissues



Ectoderm- outside layer (skin, brain, nerves)


Mesoderm- middle layer (cardiac, skeletal, blood)


Endoderm- inside layer (GI tract, lungs, pancreas)

Organogenesis- of the reproductive tract

Organogenesis- The way tissues arrange themselves into organs.



Male and female reproductive tracts are similar.


In embryonic development:



Males - gonads attach to the mesonephric (wolffian) ducts


Females - gonads don't attach, but the paramesonephric (mullerian) ducts develop into female reproductive tract

Organogenesis of the external genitals

In males the genital tubercle becomes the glans penis. Fold become penis shaft and scrotum.



In female the genital tubercle becomes the clitoris and folds become labia.



We are all born female until testosterone develops wolffian ducts in males.

Another name for birth

Parturition

Hormone cycle of birthing

Cortisol triggers labour, reduces HCG + progesterone, removes the brake on oxytocin, which causes uterine muscles to contract (positive feedback)


Prostaglandins enhance oxytocins effect.

Neonatal period

First 4 weeks after birth


Dramatic changes at a rapid rate (resp and cardio)

Effects of aging

Decline in every organ system


Degeneration of mitochondria


Limit on cell reproduction


Environmental factors


Muscle mass decreases to 50% by 80