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329 Cards in this Set

  • Front
  • Back
What is Myology?
Branch of Anatomy that deals with the muscular system.
What is contractility?
The basic property of skeletal which enables us to produce movement.
Functions of muscle
movement
enables us to move around. Locomotion - lower extremity.
manual dexterity - upper extremity
move body contents during respiration, circulation, digestion defecation, urination.
Functions of muscle
stability
maintain posture
hold articulated bones in place
Functions of muscle
communication
speech
facial expression
writing
user upper extremity ie pointing
Functions of muscle
control of body openings and passages
Sphincter muscles around eyelids, pupils, mouth control the admission of light, food and drink. Urethral and anal orifices control elimination of waste.
Functions of muscle
heat production
produce as much as 85% of body heat.
What are muscle fibers
basic structural unit of muscle.
What are fasciculi
muscle fibers grouped into bundles
What is the Endomysium
The delicate sheath which surround each individual muscle fiber and binds it to the adjacent muscle fiber
What is the Perimysium
a more dense layer which surround each fasciculi and divides the muscle into a series of separate compartments.
What is the Epimysium
dense irregular connective layer which surrounds the entire skeletal muscle and separates the muscle from surrounding tissue, organs and other muscles. Turns into the muscle tendon.
Function of connective tissue 1
connect muscle to bone or other structures
Function of connective tissue 2
provides route through which nerves and blood vessels can reach the muscle fiber
Function of connective tissue 3
provides a non contractile framework which allows the contraction of a muscle fiber to be transmitted to bone.
Talk about the microscopic anatomy of muscle fibers. List 3 important features.
1. extremely long and multinucleate with nuclei arranged around periphery. 2. Each fiber contains numerous myofibrils(contractile unit of cell)
3. each fiber is contained within a membrane known as sarcolemma.
What is hypertrophy
term used to describe the type of increase in the size of a muscle due to an increase in the size of each muscle fiber.
What is hyperplasia
term used to indicate an increase in the size of a muscle due to an actual increase in the number of muscle fibers.
What is the sarcoplasm
undifferentiated cytoplasm between the myofibrils and the other organelles of the muscle fibers.
What kind of muscles are Type 1 Fibers (dark) found in?
muscles involved in long, sustained or continued contractions: posture maintaining muscles, ocular, respiratory and masticatory muscles.
Where are Type II (light) fibers found?
places where you want quicker and more powerful contractions and are thus related to speed and strength.
Which muscle fibers have a greater capacity for Anaerobic metabolism? Aerobic metabolism?
Type II fibers need less oxygen, they have a greater capacity for anaerobic metabolism.
Type I fibers are suited for high levels of continues metabolic activity and are associated with aerobic metabolism.
Characteristics of Type I muscle fibers
large amounds of sarcoplasm and myoglobin.
extensive capillary beds
slow twitch fibers
fatigue resistant
numerous mitochondria
more fatty acids, less glycogen
atrophy with immobilization
Characteristics of Type II muscle fibers
lesser amounts of sarcoplasm and myoglobin
fewer capillary beds
fast twitch fibers
fatigue easier
fewer mitochondria
more glycogen/fewer fatty acids
atrophy with aging
What are intermediate fibers
fibers that exhibit characteristics which are somewhere between type I and type II fibers.
What is the sarcolemma
the cell membrane
What is the sarcoplasmic reticulum
an elaborate, continuous tubular network which runs both parallel and perpendicular to the myofibrils. Function to store and transport calcium ions.
What are transverse tubules
tubular invaginations of the sarcolemma which allow electrical impulses to enter the muscle fiber and make their way to the myofibrils.
what is myoglobin
red protein pigment. very similar to hemoglobin. Gives color to muscles and stores needed oxygen for muscle metabolism.
what are myofibrils
contractile apparatus of the muscle fibers. Formed from bundles of thick and thin filaments called myofilaments.
I-Bands
Light areas - hint, eyes see light.
A-Bands
Dark areas - hint, there's an A in Dark.
H-Bands
the light area in the middle of each dark band.
M-Band
Thin line down the center of each H-Band
Z Discs
thin dark line in the middle of each I-Band
Sarcomeres
smallest functional unit of a myofibril
Name the two contractile proteins
Actin, Myosin
Where is actin found
found mainly in the I-band
Where is myosin found
found mainly in the A-bands
Name the two most common regulatory proteins
Troponin and Tropomyosin
What are regulatory proteins
proteins that act as inhibitory force associated with the actin filaments that prevent the myosin heads from interacting with each other preventing indiscriminate muscular movement.
Calcium
Eliminates the inhibition caused by the regulatory proteins thus allowing subsequent muscular contractions to occur.
ATP
fuel of the muscle, its energy requirement. Allows muscles to contract.
What is rigor mortis
few hours after death when muscle fibers run out of ATP and calcium ions are not removed from the sarcoplasm. The actin and myosin cannot detach and the muscle gets locked into place.
ATP production
aerobic pathway
Takes place in mitochondria. More efficient way to produce atp in a muscle fiber. Excess energy released as heat. Prefers fatty acids to produce atp.
ATP Production
anaerobic pathway
depends on creatine phosphate and glycogen to produce atp. Creatine works right away, glycogen produces atp by glycolysis. Lactic acid is a byproduct. Provides muscle energy to get started while aerobic pathway gears up.
Exercise from a metabolic point of view(ie production of ATP)
Phase one
lasts for first few minutes. creatine phosphate and glycogen are primary fuel sources. 20% of total glycogen in body used during this phase
Exercise from a metabolic point of view(ie production of ATP)
Phase two
shift in metabolism to the more efficient aerobic metabolism and the use of fatty acids to produce ATP.
Exercise from a metabolic point of view(ie production of ATP)
Phase three
occurs as exercise intensifies. muscle fibers go back to anaerobic production of ATP and thus the utilization of the remaining stored glycogen. Lactic acid accumulates in this phase.
Ergogenic Methods to Increase Muscle Function and Size
Glycogen and Carbohydrate loading
Day 1 -
Work out to exhaustion to deplete stored glycogen in muscles.
Ergogenic Methods to Increase Muscle Function and Size
Glycogen and Carbohydrate loading
Day 2-4
Continue to exercise and eat a diet mainly high in fats and proteins. Limit carbs.
Ergogenic Methods to Increase Muscle Function and Size
Glycogen and Carbohydrate loading
Day 5-7
No exercise and eat a diet high in carbohydrates.
How does Carbohydrate loading help?
by the end of day four body will store more glycogen than normal. The the last three days the body will replenish the glycogen stores and top them off with a little bit extra.
Side effects of carbohydrate loading
light headed, dizzy, lethargic
imbalances and increases in blood pressure.
mental acuity may suffer, judgment impaired.
every gram of glycogen stored in muscle causes an increase in 3 grams of water.
Ergogenic Methods to Increase Muscle Function and Size
Caffeine
Phase 1
Amount of caffeine in two cups of coffee, ingested one hour before event may help athlete by burning fatty acids more efficiently making it easer to release fatty acids into the blood.
Ergogenic Methods to Increase Muscle Function and Size
Caffeine
Phase 1
Calcium permeability increased
How does caffeine help performance?
The effect on fatty acids should delay the utilization of glycogen and could give an advantage during endurance competitions.
Caffeine side effects
Nervousness and it can act as a diuretic.
Ergogenic Methods to Increase Muscle Function and Size
Blood Doping(induced erythrocythemia)
increases oxygen carrying capacity of red blood cells, thus increasing endurance.
Ergogenic Methods to Increase Muscle Function and Size
Blood Doping(induced erythrocythemia)
phase 1
6 weeks before withdraw 4 units of blood. Centrifuge it. Keep RBCs cold. 1 week before event thaw it out and inject it.
Ergogenic Methods to Increase Muscle Function and Size
Blood Doping(induced erythrocythemia)
Risks
Rashes, fevers
acute hemolysis (breakdown of RBCs)
transmission of viruses.
Fluid overload leading to kidney damage and intravascular clotting of blood.
Another way to increase RBC concentration?
Synthetic erythropoietin. Acts on the bone marrow to produce more red blood cells. Synthetic version mimics the natural one. Made to help patients with certain kinds of anemia. Can lead to high blood levels and can lead to death.
Ergogenic Methods to Increase Muscle Function and Size
Anabolic Steroids
What are they?
Synthetic production of male hormone testosterone. Developed to seperate anabolic effect and androgenic effects.
What is the difference between Anabolic and Androgenic?
Anabolic effects refer to the stimulation of protein synthesis, while androgenic refers to the stimulation of the male secondary sex characteristics.
When were steroids added to the IOC list of banned substances?
1975. In 1990 they were reclassified by the US government as a schedule III controlled substance.
Difference between oil based and water based steroids?
Oil based are injected and have fewer side effects but are detectable for several months. Water based are taken in a pill for. Have more side effects but cleared from system within 3-4 weeks. Patches and gels are also available.
What is stacking?
Taking several forms of steroid, used in cycles of 6-8 weeks in amounts that can be as high as 500X what would be used for therapeutic reasons.
short term side effects of steroids
headaches, dizziness nausea
acne, on the back
shrinkage of your BALLS
increased aggressiveness
gynecomastia (dev of breast tissue)
tendon damage(steroids have no effect on tendons, just muscle)
Long term side effects of steroids
cardiovascular problems, hepatic, reproductive and endocrine system problems.
Side effects of steroids in women
increase of the clitoris, development of facial hair and deepening of the voice. Tendon damage.
Physiological effects of anabolic steroids
Increased secretion of growth hormone
activates protein synthesis and prevents protein breakdown.
legitimate uses of anabolic steroids include
Restore hormonal levels in hypogonadal men. Improve mood and alleviate depression. Increases body weight, appetite and muscle mass in chronically ill patients.
What is the chemical composition of muscle?
75% water
20% protein
5% others

*eyeball is 35% protein.
Nerve Supply
Each muscle is suppled with a ________ and a _________
Motor nerve fiber and a sensory nerve fiber
Motor nerves transmit ________ or ________
Efferent or motor impulses
What is a motor unit?
The single motor neuron and the group of muscle fibers which it innervates are known as the motor unit.
The size of a motor unit is an indication of what?
How fine the control (precision) of movement can be. Eye motor units contain 2 or 3 fibers. Legs contain around 2000.
Anatomically the motor unit is divided into what parts?
Motor Neuron
Spinal nerves and peripheral nerves
neuromuscular junction
muscle fibers
What is the neuromuscular junction?
physiologically and biochemically complex portion of the motor unit. consists of a presynaptic portion and the postsynaptic portion(sarcolemme of the muscle fiber)
The presynaptic and postsynaptic portions are seperated from each other by a space known as?
the synaptic cleft
How the nerve impulse makes its way from the Presynaptic portion to the Postsynaptic portion of the neuromuscular junction:

Step 1
When nerve impulse reaches the presynaptic portion of of the neuromuscular junction, a neurotransmitter chemical ACH is released
How the nerve impulse makes its way from the Presynaptic portion to the Postsynaptic portion of the neuromuscular junction:

Step 2
ASCH will diffuse across the synaptic cleft where it will bind to very specific receptor sites on the sarcolemma of the muscle.
How the nerve impulse makes its way from the Presynaptic portion to the Postsynaptic portion of the neuromuscular junction:

Step 3
binding results in setting off an action potential down the transverse tubules which will lead to interaction between the actin and myosin causing contraction.
How the nerve impulse makes its way from the Presynaptic portion to the Postsynaptic portion of the neuromuscular junction:

Step 4
When the ACH has completed its task, it will be broken down by an enzyme known as acetylcholinesterase. This enzyme destroys the ACH by degrading it down into acetate and choline.
What is myesthenia gravis?
most common neuromuscular junction disorder. Autoimmune disorder. The body produces abnormal antibodies which damage and destroy the ACH receptor sites on the sarcolemma.
How does nicotine affect the neuromuscular junction?
It competes with ACH receptors in binding to ACH receptor sites. It's actions are much more prolonged than ACH.
how does snake venom effect the neuromuscular junction?
Prevents ACH from binding to the receptor sites, because the molecules of the venom bind to the ACH receptor sites.
How do organophosphates effect the neuromuscular junction?
chemicals such as parathion and malathion which are found in insecticides. They activate the ACHe enzyme so ACH can no longer be rapidly hydrolyzed resulting in an accumulation of ACH at the post synaptic portion of the junction.
How does botulin toxin effect the neuromuscular junction?
blocks the release of ACH from the presynaptic portion of the neuromuscular junction. Leads to rapid and progressive muscle weakness.
T or F
Are the muscle fibers of a single motor unit considerably scattered throughout the width and length of the muscle?
True
what are the two functions of sensory nerve fibers for skeletal muscle?
Pain, proprioception
why are muscle spindles classified as proprioceptors?
They detect stretch in a muscle and trigger skeletal muscle reflexes
What are the differences between intrafusal and extrafusal fibers?
Intrafusal fibers have both efferent and afferent nerve fibers associated with them. Extrafusal fibers have only efferent nerve fibers.
What is the third most complex sensory organ in the human body?
muscle spindle
What is the golgi tendon organ?
detects stretch in a tendon and triggers a reflex that inhibits muscle contractions to avoid muscle or tendon injury
What is the origin?
end of the muscle which attaches to the more or less stationary part of the skeleton
What is the insertion?
end attached to the portion of the skeleton which moves when the muscle contracts. Attachment is always by a tendon.
What is the belly?
term for the intermediate fleshy portion of the muscle.
What is a tendon
connective portion of a muscle which attaches to a bone
What is a tendon composed of?
collagen fibers
What is tensile strength?
defined as the load necessary to rupture a given material when pulled in the direction of its length.
Tendons give muscle four advantages.
What is the first one?
improves leverage by concentrating the force of a muscle on a small area
Tendons give muscle four advantages.
What is the second one?
economizes space and maintains limb conformity
Tendons give muscle four advantages.
What is the third one?
acts as a dampin tissue to absorb shock and limit potential damage to bone and muscle.
Tendons give muscle four advantages.
What is the fourth one?
flexible so that they can bend at joints.
what are sharpey's fibers?
collagen fibers which penetrate the bone
T or F
Sharpeys fibers are so strong that even with severe traction injuries the tendon does not pull out of the bone. Instead, an avulsion fraction occurs.
true
T or F
Do tendons have motor innervation?
False. They have no motor function so they do not receive any efferent innervation
What is a bursa?
sac of connective tissue that is filled with synovial fluid. Facilitates movement by minimizing friction.
What is Fascia?
The musculature of the body is invested and seperated from the skin and from each other by sheets of connective tissue known as Fascia.
What is superficial fascia?
lies deep to the skin and contains blood vessels, lymphatics, nerves, varying amounts of adipose tissue.
Deep fascia is divided into 3 layers. What are they?
an investing layer of muscle called epimysium, intermuscular septum, and a retinaculum.
What is the intermuscular septum
where epimysium of one muscle meets the epimysium of another muscle.
What is the retinaculum.
thickened band of deep fascia which is found at joints and functions to bind down tendons and nerves that cross the joint.
what is the parallel or strap arrangement
muscles where the fibers run approximately the whole length of muscle, parallel to the long axis.
what is the pennate muscle arrangement
muscles whos fibers run oblique to the long axis.
what is the unipennate or bipennate muscle arrangement
where the tendon lies along one side of the muscle and the muscle fibers pass obliquely to it, or when the tendon lies in the center of the muscle fibers.
Endurance type 1 fibers are typically in what arrangement? what about power type 2 fibers?
Pennate for type 1, parallel for type 2
What is a prime mover or agonist?
muscle or muscles which are most responsible for carrying out a particular action.
What is a synergist?
assist the prime mover in performing its action. Stabilizes a joint which the mover passes over but does not move. Keeps the bone or origin of the mover steady. This is sometimes called a fixator.
What is an antagonist?
muscle that produces the opposite effect from the agonist.
What is reciprocal innervation?
when a muscle contracts(agonist) its antagonist automatically relaxes.
What is Co-reflex phenomenon?
In a newborn (especially a premature infant) both agonist and antagonist contract at the same time. Also seen in individuals with sensory nerve damage.
No account of the role of muscles would be complete without the considering the influence of what?
gravity
What is muscle atrophy
when the muscle becomes smaller and weaker.
what pathology of the CNS can cause muscle atrophy?
Amyotropic lateral sclerosis
What pathology of the peripheral nervous system can cause muscle atrophy?
Guillain Baire syndrom
What pathology of the individual muscle fibers can cause muscle atrophy?
Muscular dystrophies
Can prolonged immobilization of the joints or chronic joint disorder cause muscle atrophy?
Yes
What is Ischemic Necrosis?
Term used to designate any diminishing of the arterial supply to a muscle which will result in the loss of muscle fibers within a few hours.
What is muscle contracture?
If a muscle remains shortened(contracted) for a prolonged period of time it will develop a persistent and sometimes permanent shortening.
What diseases can cause contracture?
Polio, muscular dystrophy, cerebral palsy
Muscles can regenerate. What cells facilitate this and how do they do it?
undifferentiated satellite cells are found between the endomysium and the muscle fiber. They can differentiate and help with the repair and regeneration of muscles.
How does muscular dystrophy impact satellite cells?
it prevents them from replacing injured muscle fibers.
Reasons why muscle tissue degenerates over time
muscle fibers have fewer myofibrils
sarcomeres are fewer and disorganized
Fewer mitochondria, less ATP
Reduced blood supply
fewer motor neurons in CNS
What is the upper extremity?
a multi jointed lever that is freely movable on the trunk at the shoulder joint. It is comprised of the shoulder girdle and the free limb.
What two bones does the shoulder girdle consist of?
Scapula, clavicle
What does the free limb consist of?
1. arm or brachium between the shoulder joint and elbow joint.
2. forearm or antebrachium between elbow and wrist joint.
3. hand or manus which is distal to the wrist joint.
What does the word clavicle mean?
little key
the clavicle forms the boundary between two well marked depressions. What are they?
supraclavicular fossa and infraclavicular fossa.
How is the clavicle different in men and women?
for females the bone is shorter, thinner, less curved and smoother.
Is the clavicle present in all vertebrae(subphylum in which man is classified)?
No, it is only present in those vertebrae that use the hand for manual dexterity.
Main functions of the clavicle:
1.
transmit forces from upper extremity to axial skeleton
Main functions of the clavicle:
2.
act as a brace, holding the arm free from the trunk.
What is ossification?
process by which embryonic connetive tissue is replaced by bone cells.
What is intramembranous ossification?
ossification in which bone cells replace a primitive type of connective tissue known as mesenchyme. Occurs in the axial skeleton.
What is endochondral ossification?
ossification in which bone cells replace a very well developed type of connective tissue known as hyaline cartilage. Occurs in the appendicular skeleton.
How is the clavicle unique as far as ossification is concerned?
it is the first bone to undergo ossification in the fetus around teh 5th or 6th week. It undergoes intramembranous oss at the center of the bone first, then endochondral at around 17 years of age.
When does the clavicle finish growing?
at around age 25
T or F
the clavicle one of the most frequently fractured bones in the body?
True
Where do fractures occur on the clavicle?
normally in the first lateral third of the bone near the area of the first curvature, which is the weakest part of the bone.
What is cleidocranial dysostosis?
hereditary condition in which ossification is defective. The clavicle is missing or abnormally formed. Bilateral in most patients.
Where is the scapula found?
between the second and seventh ribs and the first and seventh thoracic vertebrae.
What other bones does the scapula articulate with?
Head of the humerus to form the shoulder joint and with the acromial end of the clavicle to form the acromioclavicular joint.
How many ossification centers does the scapula have?
7 ossification centers. 1 primary and 6 secondary.
When is the scapula completely ossified?
between 15 and 18 years of age
describe the development of the clavicle during the fetal stages.
primary center of bone develops during the 8th week. The 6 secondary ossification(2 for acromion, 2 for coracoid, 1 for the medial border and 1 for inferior angle) will develop from right after birth to the teen years.
What is the clinical arm?
area from the acromion process of the scapula to the lateral epicondyle of the humerus. Differs from the anatomical arm which is the area between the shoulder and elbow joint.
What is the most commonly fractured part of the scapula?
the acromion process
What is Sprengel's deformity?
an undescended scapula brought about by attachment to cervicle vertebrae by either bone, cartilage or fibrous attachment.
What is Os Acromidae?
failure of the acromion process to fuse with the rest of the bone.
What are mammary glands?
Toys. Just kidding. They are paired cutaneous sweat glands which are found in both sexes bu are rudimentary and functionless in males.
Primary functions of the mammary gland:
1.
Provides nourishment to the infant.
Primary functions of the mammary gland:
2.
Provides protection against certain types of diseases in infants. (immune benefits)
Where are mammary glands located?
they are situated on the ventral aspect of the thoracic wall where they lie embedded in superficial fascia.
What is the axillary tail?
portion of the mammary gland that projects into the axillary region.
What is the nipple?
papillae like projection which contain the opening of the lactiferous ducts.
how many lactiferous ducts are there per lobe?
a single duct per lobe.
What is the lactiferous sinus?
Where the lactiferous ducts expand and enter the nipple.
Is the mothers milk sucked by the infant?
no, compression forces cause the accumulated droplets to be sucked into the infants mouth.
Each nipple is composed of:
1.
smooth muscle fibers, the contraction of which produce erection of the nipple.
Each nipple is composed of:
2.
tactile sense organs, which render the nipples sensitive to mechanical stimulation.
Each nipple is composed of:
3.
numerous pigment cells, which impart color
What is the areola?
This is the circular part of the skin surrounding the nipple.
how does the color of the areola differ pre and post pregnancy?
the areola is usually rosy-pink in a woman who has never been pregnant, but during pregnancy it becomes brownish or even black in color.
What do the sebaceous glands do in the areola?
they secrete an oil substance that provides a protective lubricant for the areola and nipple during lactation.
How many lobes are found in the mammary gland?
20 lobes.
what is the suspensory ligament?
a fibrous septa of connective tissue that seperates each lobe from the others.
How are lobes subdivided?
into lobules which consist of alveoli
What are alveoli? What are they lined with?
secretory portion of the mammary gland and are lined with secretory cells.
prior to pregnancy, the alveolar tissue is functionless and said to be in what kind of state?
resting or inactive state
What changes occur in the mammary gland at puberty?
increase in size rapidly
What changes occur in the mammary gland at each menstrual period?
tend to enlarge slightly and to exhibit tenderness
What changes occur in the mammary gland at each pregnancy?
become enlarged and functional, attaining their development during lactation. After lactation they return to normal size.
What are the hormones that influence the development of the mammary glands?
Estrogen, progesterone, prolactin, oxytocin
what secretes estrogen and how does it influence the development of the mammary gland?
secreted by ovary and placenta and it promotes the growth of the duct system of the mamary gland.
what secretes progestrone and how does it influence the development of the mammary gland?
secreted by the ovary and placenta, promotes the growth of secretory cells.
what secretes prolactin and how does it influence the development of the mammary gland?
secteted by the anterior pituitary and promotes the production of milk after birth.
what secretes oxytocin and how does it influence the development of the mammary gland?
secreted by the posterior pituitary and promotes the release of milk.
True or False
During pregnancy estrogen and progesterone suppress the development of milk.
True
They promote the development of alveoli but suppress milk production. After birth there is a decrease in estrogen and progesterone.
What is the colostrum?
first secretions from the functional mammary gland. It is creamy white to yellowish fluid.
When is colostrum secreted?
during the last few weeks of pregnancy and continues for about the first week of nursing.
What is colostrum rich in? It functions to do what?
immunoglobulins and lactoferrin. It functions to impart immune protection and a growth factor affecting the infant's intestinal tract.
What is transitional milk
present from day 6 to 15, it has lower immunoglobin compared to colostrum bu higher amounts of lactose and fat.
when is mature milk present and what is it composed of?
present from day 15 to weaning and it is composed of 88% water, 7% lactose, 4% fat and 1% protein.
What is an inverted nipple?
aka retracted nipple (may be congenital or a recent event)If it is a recent event the cause may be an underlying carcinoma pulling on the lactiferous duct.
What are supernumerary nipples?
extra nipple which may or may not be associated with mammary gland tissue.
Give the 4 causes of breast cancer
family history in mother or sister
never having had a child or having first child after age 35
exposure to ionizing radiation
excessive intake of fat and red meat
Each month after the menstrual period, the mammary glands should be checked for three things. What are they?
lumps, dimpling of the skin, nipple retraction and discharge
What is chronic cystic mastitis(fibrocystic disease)
benign tumor commonly found after the menstrual cycle and during periods of hormonal irregularity. Difficult to distinguish from benign cyst and cancerous tumor.
What is galactorrhea or nipple discharge.
secretions not associated with pregnancy. Not due to any underlying pathology. May be due to medication, hormonal abnormalities and trauma to chest wall.
Can medication be transmitted in breast milk?
Yes, any medication the mother takes can be transmitted to the child.
Can breast feeding be counted upon as a reliable method of contraceptive?
No because the levels of prolactin are unpredictable.
What is gynecomastia
enlargement of the breast in a male. Common at puberty. Uncommon after puberty.
How many ossification centers does the humerus have?
8 ossification centers. 1 primary and 7 secondary.
Where are the ossification centers of the humerus?
primary center for the shaft and secondary centers for the head, greater tubercle, lesser tubercle, medial epicondyel, lateral epicondyle, trochlea and capitulum.
When is the humerus completely ossified?
age 18-20 in females and 20-22 in males.
What are the main areas of fracture on the humerus?
anatomical neck, surgical neck, greater tubercle, lesser tubercle, shaft and distal end.
Several nerves and blood vessels are vulnerable to damage with fractures of the humerus. What are they?
Surgical neck: axillary nerve, humeral circumflex vessels
shaft: radial nerve
distal end: median nerve, ulnar nerve, brachial blood vessels.
List the four movements of the scapula
elevation, depression, abduction/protraction, adduction/retraction.
Explain scapula elevation
upward movement of the scapula while the scapula remains approximately parallel to the vertebral column.
Explain scapula depression
the return to normal from a position of elevation
explain scapula abduction/protraction
a lateral movement of the scapula away from the vertebral column with the medial border remaining parallel to the column.
explain scapula adduction/retraction
a medial movement of the scapula toward the vertebral column.
Movements of the humerus
flexion, extension, abduction, adduction, medial rotation, lateral rotation, circumduction.
explain humerus flexion
forward movement of the humerus
explain humerus extension
backward movement of the humerus (reverse of flexion)
explain humerus abduction
movement of the humerus laterally away from the body
explain humerus adduction
movement of bringing the humerus back toward the body(medial movement)
explain humerus medial rotation
humerus is turned inward toward body
explain humerus lateral rotation
humerus is turned outward away from body
explain humerus circumduction
rotational movement around a joint
Give the 3 origins of the pectoralis major.
clavicle(clavicular portion)
sternum and upper ribs(sternocostal portion)
external oblique muscle(abdominal portion)
Where does the pectoralis major insert?
lateral aspect of the inter tubercular groove.
What movements are associated with the humerus and the pectoralis major?
adduction and medial rotation of the humerus
How does the pectoralis major help with inspiration?
by elevating the rib cage when the humerus is stabilized or fixed. Used by individuals with respiratory difficulty or an exhausted athlete.
What does the clavicular portion of the pectoralis major do?
flexes the humerus at the shoulder joint.
What does the sternocostal portion of the pectoralis major do?
extends humerus at the shoulder joint.
What is the nerve supply of the pectoralis major?
Medial (C8-T1) and lateral pectoral (C5-C7) nerves.
Explain rupture of the pectoralis major.
a rare injury occurs when excessive stress causes a tearing of the tendon or possibly an avulsion fracture at its insertion. Athletes describe hearing a pop or a snap.
Explain the absence of pectoralis major muscle.
not common, but when it occurs no disability results. However, the anterior fold of the axilla is missing.
What is poland's syndrome?
a condition in which both the pectoralis major and minor muscles are missing and there is atrophy of the mammary glands and the absence of several ribs.
What is the origin of the pectoralis minor
upper ribs
What is the insertion of the pectoralis minor
coracoid process/scapula
How does the pectoralis minor act on the clavicle?
pulls the clavicle medially thus stabilizing the sternoclavicular joint (especially when hanging by your head.)
The pectoralis minor is a protective cusion between what?
fractured clavicle and underlying vessels.
What is the nerve supply of the pectoralis minor?
nerve to the subclavius (C5-C6)
What is the axilla?
space between the arm and chest wall which is in the shape of a truncated pyramid.
What is the apex of the axilla?
upper end. It is a triangular space bounded by the clavicle, scapula and the first rib.
What is the base of the axilla?
lower end. it is made up of skin and fascia.
What are the folds of the axilla
anderior and posterior folds.
The anterior wall of the axilla is formed by?
the pectoralis major
the posterior wall of the axilla is formed by?
the scapula and the subscapularis muscles, tendon of the latissimus dorsi, and the teres major.
What is the medial wall of the axilla formed by?
serratus anterior and the upper ribs.
what is the lateral wall of the axilla formed by?
medial aspect of the arm(bicipital furrow)
list the contents of the brachial plexus of which there are 5.
brachial plexus, axillary artery and vein, axillary lymph nodes and adipose tissue.
What is the axillary sheath?
the nerves and blood vessels found in the axilla are closely grouped together and enclosed in a layer of fascia known as the axillary sheath.
The dorsal scapular nerve provides motor supply to what two muscles?
Rhomboid and levator scapula
The long thoracic nerve provides motor supply to what muscle?
serratus anterior
The suprascapular nerve provides motor supply to what two muscles?
supraspinatus and infraspinatus
The suprascapular nerve provides articular supply to what joint?
the shoulder joint
the nerve to the subclavius provides motor supply to what muscle?
subclavius muscle
The lateral pectoral nerve provides motor supply for what muscle?
pectoralis major
The musculocutaneous nerve passes through what muscle?
the coracobrachialis. It then runs between the biceps brachii and brachialis muscle.
The musculocutaneous nerve provides motor supply to what three muscles?
coracobrachialis, biceps brachii, and brachialis
The musculocutaneous nerve provides articular supply to what joint?
elbow joint
the musculocutaneous nerve provides cutaneous supply to what aspect?
lateral aspect of the forearm
The medial pectoral nerve provides motor supply to what two muscles?
pectoralis major and pectoralis minor
The medial brachial cutaneous nerve provides cutaneous supply to what aspect?
medial aspect of the arm
the medial antebrachial cutaneous nerve provides cutaneous supply to what aspect?
medial aspect of the forearm.
The ulnar nerve provides motor supply for what 3 muscles?
flexor carpi ulnaris and the medial half of the flexor digitorum profundus and muscles associated with the 5th digit known collectively as the hypothenar muscles.
The ulnar nerve provides articular supply for what 2 joints?
elbow and wrist joints.
The ulnar nerve provides cutaneous supply to what aspects?
medial aspect of the palm and dorsum of the hand. skin of digit five and part of digit four.
the median nerve provides motor supply to what 8 muscles?
pronator teres, flexor carpi radialis, palmaris longus, flexor digitorum superficialis, flexor pollicis longus, pronator quadratus, and the lateral half of the flexor digitorum profundus.
The median nerve provides articular supply to what 2 joints?
elbow and wrist joint
The median nerve provides cutaneous supply to what aspects?
lateral 3/4 of the palmar surface of the hand and the skin of the first 3 1/2 digits.
the upper subscapular nerve provides motor supply to what muscle?
subscapularis
The lower subscapular nerve provides motor supply to what two muscles?
subscapularis and teres major
The thoracodorsal nerve provides motor supply to what muscle?
the latissimus dorsi
The axillary nerve provides motor supply to what two muscles?
deltoid and teres minor
The axillary nerve provides articular supply to what joint?
shoulder joint
the axillary nerve provides cutaneous supply to what aspects?
a specific articular branch of the nerve which is known as the lateral brachial cutaneous supplies skin on the lateral aspect of the arm.
The radial nerve provides motor supply to what muscles?
triceps brachii and all the posterior forearm muscles.
The radial nerve provides articular supply to what two joints?
the elbow and the wrist joints
What is a dermatome?
the area of the skin supplied by a sensory root of a spinal nerve
dermatome of C4 covers what area?
skin over the tip of the shoulder
dermatome of C5 covers what area?
lateral(radial) side of the arm
dermatome of C6 covers what area?
radial side of the forearm; digit one and two
dermatome of C7 covers what area?
skn of the hand; digit three
dermatome for C8 covers what area?
medial (ulnar side of the forearm; digits four and five)
dermatome of T1 covers what area?
ulnar side of the arm
dermatome for T2 covers what area?
skin of the axilla
What is a prefixed brachial plexus?
plexus in which C4 is the superior spinal nerve root forming the plexus. C8 would be the most inferior nerve root.
What is a postfixed brachial plexus?
plexus in which C6 is the superior spinal nerve root forming the plexus. in this type of plexus, T2 would be the most inferior spinal root.
What is paralysis
complete loss of muscular movement
what is paresis
movement can be performed but is weak
what is anesthesia
partial or complete loss of sensation with or without loss of consciousness
what is paresthesia
loss of cutaneous sensation
Where is the dorsal scapular nerve found?
descends down the back dep to the rhomboids and levator scapula muscle.
Where is the suprascapular nerve found?
passes laterally across the cervical region deep to the trapezius and deep to the muscles associated with the posterior aspect of the scapula. Passes from the supraspinous fossa to the infraspinous fossa via an opening in the spine of the scapula.
where is the nerve to the subclavius found?
descends posteriorly to the clavicle and often gives a branch to the phrenic nerve which is known as the accessory phrenic nerve.
Where is the lateral pectoral nerve found?
first nerve to come off of the lateral cord and often communicates directly with the medial pectoral nerve.
Where is the musculocutaneous nerve found?
terminal branch of the lateral cord. As it leaves the axilla it always passes through the belly of the coracobrachialis muscle and then runs between the biceps brachii and brachialis muscle.
Where is the medial pectoral nerve found?
the first small nerve coming off the medial cord.
Where is the ulnar nerve found?
descends between the axillary artery and vein down the medial aspect of the arm. As the nerve descends down the medial aspect of the forearm, it is deep to the flexor carpi ulnaris muscle. The nerve will cross the wrist joint and enter the palm.
Where is the median nerve found?
formed from the union of more than one cord. Nerve descends along medial aspect of the arm, lateral to the ulnar nerve. Enters the forearm by passing between the two bellies of the pronator teres muscle and then descends down the middle of the forearm.
Where is the thoracodorsal nerve found?
runs down the lateral aspect of the thoracic cage, just lateral to the long thoracic nerve.
Where is the axillary nerve found?
smaller and more lateral of the terminal branches of the posterior cord. Associated with the surgical neck of the humerus which it encircles.
Where is the radial nerve found?
descends from the axilla to the middle of the arm where it comes in contact with the humerus at the spiral groove. it then descends into the forearm where it divides into a superficial and deep branches.
What is Erb Duchenne Palsy
Most common type of injury to the plexus. Results from excessive increase in angle between neck and shoulder. Injures C5 and C6.
How are injures to the upper root caused(Erb Duchenne Palsy)
1.
difficult birth process. excessive stretching of the neck of the infant. Seen a few hours after birth.
How are injures to the upper root caused(Erb Duchenne Palsy)
2.
following a fall or a blow on the shoulder. Shoulder hits something but the head continues to move.
How are injures to the upper root caused(Erb Duchenne Palsy)
3.
Heavy weight falls on your shoulder and produces a traction injury. Struck by a falling branch.
What nerves could be involved if C5 and C6 are injured?
Suprascapular, nerve to the subclavius, musculocutaneous, axillary, median, radial, dorsal scapula, long thoracic, lateral pectoral and subscapular.
What complications will injuries to the upper root cause?
disabled shoulder movement, but a reasonably functional nhand. Loss of sensation in the area of the C5 and C6 dermatomes.
What nerves are impacted by injury to the lower roots (Klumpke's Palsy)?
Occurs from injury to C8 and or T1
What are causes of injury to the lower roots (Klumpke's Palsy)?
1.
individual falling from a height and clutching an object to save themselves.
What are causes of injury to the lower roots (Klumpke's Palsy)?
2.
forceful pull of the shoulder of an infant during the birth process.
What nerves may be involved in an injury to the lower roots (Klumpke's Palsy)?
ulnar, median, radial, medial brachian and antebrachial cutaneous, medial pectoral, and thoracodorsal.
What problems will people have after injuries to the lower roots of the brachial plexus?
Problems with movements at the wrist joint and digits and thus greatly disabled use of the hand.
What are the cervical ribs?
a longer than normal transverse process of a cervical vertebrae may cause problems with the spinal nerve roots of the plexus.
What can cause compression of the cords of the brachial plexus?
prolonged hyperabduction of the arm during certain manual tasks like painting a ceiling.
What is thoracic outlet syndrome?
condition where there is both compression of the cords of the brachial plexus and the axillary artery.
What symptoms are shown with thoracic outlet syndrom?
both neurological and vascular. Nerological symptoms include pain and paresthesia while vascular sypmtoms are usually decreased skin temperature and fatigue of the limb.
How does the axillary artery get its name?
it is a direct continuation of the subclavian artery. The blood vessel changes its name to the axillary artery when the vessel passes under the clavicle and enters the axilla. It becomes the brachial artery about an inch or so below the level of the surgical neck of the humerus.
What are the six specific branches of the axillary artery?
superior thoracic, thoacoacromial, lateral thoracic, subscapular, anterior and posterior humeral circumflex.
what does the superior thoracic artery supply
first branch off the axillary. It supplies the pectoralis major, subclavius muscle and part of the superior thoracic wall.
What does the thoracoacromial artery supply?
short trunk which curls around the upper medial border of the pectoralis minor and divides into 4 branches (acromial, pectoral, clavicular, and deltoid)
What does the lateral thoracic artery supply?
appears along the lateral border of the pectoralis minor. It supplies the serratus anterior, large portion of the mammary gland, intercostal muscles and part of the pec major.
what does the subscapular artery supply?
largest branch of the artery and found parallel and lateral to the lateral thoracic artery. It divides into two branches, the thoracodorsal and circumflex scapular.
what does the thoracodorsal artery supply?
latissimus dorsi and subscapularis
what does the circumflex scapular artery supply?
muscles associated with the dorsum of the scapula.
what do the anterior and posterior humeral circumflex arteries supply?
form a ring or circle around the surgical neck of the humerus. They supply the deltoid muscle, teres major and minor, shoulder joint, and proximal part of the humerus.
True or False
all arteries have accompanying feins, thus there is a axillary vein which becomes the subclavian vein etc
true
How can an aneurysm affect the brachial plexus?
it can compress the trunks and or cords causing pain and loss of sensation in the areas supplied by the nerves. Seen in baseball pitchers due to forceful and rapid arm movement.
What is a lymph vessel?
vessel of the lymphatic system that contains fluid known as lymph.
True or False
lymph fluid and interstitial fluid are essentially the same thing?
true.
What is a lymph node?
function to filter lymph fluid and produce lymphocytes to destroy bacteria, viruses, and cancer cells.
What are the axillary lymph nodes?
embedded in the fascia and adipose tissue of the axilla and are located around the brachial plexus and axillary vein. Number around 20-30.