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33 Cards in this Set

  • Front
  • Back
What do dermatophytes infect?
Infect the keratinized layer of hair, skin, or nails
What kind of dermatophytes cause the most mild inflammation?
Anthropophilic dermatophytes
What kind of dermatophytes cause marked inflammatory reactions in humans
Zoophilic dermatophytes
Geophilic dermatophytes
~ 58% of the dermatophyte isolated are
Trichophyton rubrum
Other dermatophytes
27% are T. mentagrophytes
7% are T. verrucosum
3% are T. tonsurans
Tinea capitis
Tinea pedis
Tinea manuum
Tinea cruris
Tinea barbae
Tinea corporis
Tinea unguium
Feet (athletes foot)
Beard, hair
Describe a tinea lesion
Erythematous, scaly plaques with well-defined
Clear center
What is this assoc with Tinea capitis?

Arthroconidia on the outside of the hair shaft
Often fluoresce
Destroys the cuticle of the hair
What is this assoc with Tinea capitis?

Arthroconidia in the hair shaft
Hair cuticle remains intact
Does not fluoresce
What is this assoc with Tinea capitis?

Usually associated with T. schoenleinii
Crusting and hair loss
What is the cause of this tinea capitis?

Erythematous, scaly plaques in the scalp, developed after getting a very cropped hair cut
The lesions may produce significant hair loss
Scarring may occur if inflammation is severe
A kerion of the scalp which is often mistaken for a bacterial abscess
zoophilic organisms
A kerion of the scalp
Trichophyton verrucosum
most common nosocomial fungal pathogen
Predisposing factors for Vaginal candidiasis
Antibiotic therapy
Who gets oral thrush
infants and immunocompromised patients
Superficial mycoses
Tinea versicolor
Tinea nigra
White & black piedra
Etiologic agent of Tinea versicolor
Malassezia furfur (Pityrosporum obiculare)
When does pt notice the infection?
Noticed in the summer because lesions don’t tan
Dx of tinea versicolor
Clinical appearance
Fluoresces under Wood’s light
Skin scrapings (spaghetti & meatballs)
Etiologic agent of Tinea nigra
Phaeoannellomyces werneckii
What part of the world is P. werneckii seen?
Mostly seen in the tropics
Quick description of P. werneckii
Brown to black lesion on hands and feet
White or black nodules along the hair shaft
Etiologic agents:
Trichosporon beigelii (white)
Piedraia hortae (black)
White and Black Piedra
Subcutaneous mycoses
MC subQ mycosis in US
What's the fungus name?

Dimorphic fungus
In soil and on plants (rosebushes and mulches)
Occupational disease of gardeners, florists, farmers etc.
Sporothrix schenckii
What do you see in biopsy of S. Schenckii
cigar-shaped yeasts
asteroid bodies (yeast cell surrounded by rays of eosinophilic material containing antigen-antibody complexes, complement, & tissue components)
What is most reliable method of diagnosis
What is the name of fungus causing Chromoblastomycosis ?

dematiaceous fungi
plant debris
Can occur in southern US (rare)
Scaly, wart-like structure on foot or leg, with pigmented flecks seen within the lesion
Chronic, slow growing, painless but disfiguring
Lesions contain sclerotic bodies (thick-walled cells with horizontal &/or vertical septa)
Culture can take up to 6 weeks
Phialophora & Cladosporium
In Chromoblastomycosis, KOH examination of the pigmented flecks showed WHAT?
golden-yellow coloured septate spherical bodies (sclerotic bodies or medlar bodies or copper penny bodies).
In Chromoblastomycosis, brown sclerotic bodies divide HOW?
by binary fission and not by budding
What's this?

Chronic, subcutaneous tumor characterized by suppuration and abscess formation
Draining sinuses contain pus and microcolonies of the etiologic agent
Culture or examine granules from draining sinuses to distinguish between bacterial or fungal etiologic agent
Fungal mycetoma may require excision of lesion or amputation
What is Characterized by the triad of tumefaction, draining sinuses, and the presence of grains in the exudate.
Madura Foot
Mycetoma can be caused by WHAT?
true fungi (eumycetic mycetomas), filamentous bacteria of the order Actinmycetales (actinomycetic mycetoma), and other bacteria (botrymycosis).