Gram Negative Vibroid Bacteria

Front 1

What is the best way to differentiate between Campylobacter and Helicobacter

Back 1

Presence of Flagellar Sheets
Camp - Absent
Heli - Present

Front 2

What is required for Campylobacter growth

Back 2

5 -10% O2
5 - 10% CO2
80 - 90% N2

Front 3

What shaped and Gram Stain are Campylobacter

Back 3

Curved Spiral, motile/unsheathed flagella, gram -

Front 4

What is the metabolism of Campylobacter

Back 4

Nonfermentative/nonoxidative

Derive energy from the use of amino acids and 4-6-carbon intermediates of the TCA

Front 5

What diseases are campylobacter associated with

Back 5

gastroenteritis, abortions in cows, sheep, humans, sepsis, meningitis, periodontal disease and proctitis (homosexual)

Front 6

What is the habitat of Campylobacter

Back 6

Campylobacters are normal flora in GI tracts

Front 7

What is a good test to differentiate between Camplyobacter coli and Campylobacter jejuni

Back 7

Test Hippurate
C. coli Hippurate -
C. jejuni Hippurate +

Front 8

How many types of transmission are there for Campylobacter

Back 8

2 exogenous and endogenous

Front 9

Exogenous Transmission

Back 9

acquire from handling infected animals or through the fecal-oral route

Front 10

Endogenous Transmission

Back 10

Transmission from mother to fetus through genitourinary tract

Front 11

What are pathogenic factors of Campylobacter

Back 11

LPS - protects from stomach acid
Flagellar Motion/Shape - passes through mucous membrane
Distending Cytotoxin -stops cell divisioin
Enterotoxin - similar to cholera, ETEC, and LT
Adhesins - attachment

Front 12

Symptoms of Campylobacter infection

Back 12

watery diarrhea, bloody diarrhea, extraintestinal disease
80% of patients are asymptomatic

Front 13

Diseases caused by campylobacter

Back 13

Acute Enteritis, Appendicitis like syndrome, Bacteremia, septic abortion, Reactive arthiritis

Front 14

Lab Idnetification of campylobacter

Back 14

From stool: Campy-Thio, Campy-BAP in 5% O2, 10% CO2, 85% N2

Front 15

What is Campy-BAP?

Back 15

10% Sheep's Blood, Vancomycin (inhibits Gram +), trimethoprim (e. coli), polymyxin B, cephalothin, amphotericin B (fungi), in Brucella Agar base

Front 16

What is the most important pathogen of campylobacter/ what does it causes

Back 16

C. jejuni
Isolated from stoll 7 times more than Salmonella shigella
Guillain-Barre syndrome

Front 17

Treatment for Campylobacter

Back 17

usually just fluid and electrolyte replacement.
If antibiotics: erythromycin and quinolones

Front 18

_______ causes peptic ulcers

Back 18

Helicobacter

Front 19

Growth environment contains _____, _____, and ______ at _____ temperature

Back 19

10% CO2, 5% O2, 85% N2
35-37 C, 42 C
High Humidity

Front 20

_____cytotoxin in H. pylori causes _____

Back 20

Vacuolating, cellular damage

Front 21

_____ causes activates signal transudction.

This can cause ____

Back 21

Cag A
cellular growth, maybe cancer

Front 22

H. pylori can be cultured on :_______ + 5% Sheep Blood
________+ 7% Horse Blood
________ + antibitic

Back 22

Mueller Hinton
Brain Heart Infusion
Thayer-Martin

Front 23

___ and helps protect H. pylori by hydrolizing Urea to __ and __.

Back 23

Urease
ammonia
CO2

Front 24

_____, _____, and _____ are treatments for H. pylori

Back 24

Bismuth, Amoxicillin, and Tetracyclin