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15 Cards in this Set

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Vibrio species:
(1) oxidase
(2) motility
(3) serogrouping
(1) oxidase-pos
(2) single polar flagellum
(3) O and H antigens
Vibrio cholerae

Epidemiology:
(1) human disease serotypes
(2) historic epidemics of what?
(3) risk factors
(4) infection source
(1) O1, O139
(2) diarrhea
(3) H. pylori, O blood type
(4) contaminated water, food
Vibrio cholerae

Pathogenesis:
(1) pathogen or toxin-caused?
(2) effects of toxin
(1) toxin
(2) decreased Na+ absorption, increased Cl- secretion
Vibrio cholerae

Symptoms:
(1) pos sx
(2) neg sx
(3) gen appearance
(4) serious complication
(5) unique in children
(6) pregnant woman prognosis
(1) watery diarrhea, vomit
(2) strain, tenesmus, abd pain
(3) sunken eyes, dry mucous
(4) acute renal failure
(5) seizures, fever
(6) fetal loss in 50% cases
Vibrio cholerae

Treatment:
(1) FIRST thing to do
(2) type of drugs
(3) vaccine
(1) rehydration (Ringer's lactate)
(2) antimicrobials
(3) ideal vaccine not available
Vibrio parahaemolyticus:
(1) sources
(2) pos sx
(3) deaths in which pop?
(4) treatment
(1) shellfish
(2) watery diarrhea, desentery, gastro
(3) elderly, kids, immunocomp'd
(4) tetracyclines, quinolones
Vibrio vulnificus:
(1) mortality rate
(2) natural habitat?
(3) population affected?
(4) pos sx
(5) treatment
(1) 25%
(2) marine environ
(3) immunocomp'd
(4) fever, chills, low BP, skin lesions
(5) tetracyclines, quinolone
Campylobacter

General Characteristics:
(1) best growth conditions
(2) sources
(3) isolation techniques
(1) microaerophilic, C. jejuni = 42 C
(2) undercooked meat
(3) filtration
Campylobacter:
virulence factors (5)
(1) flagella
(2) high-MW plasmid
(3) PEB1 antigen
(4) C. jejuni = O antigen
(5) C. fetus = serum-resistant capsule
Campylobacter

Treatment:
(1) diagnosis
(2) sx for presumptive therapy
(3) resistance
(1) stool, blood culture
(2) fever, bloody diarrhea, >8 BMs/day
(3) increasing to macrolides, quinolones
Campylobacter jejuni:
(1) common sx
(2) commonly affected age group?
(3) clinical manifestations (6)
(1) diarrhea
(2) under 2 years
(3) acute enteritis,
acute colitis,
pseudoappendicitis,
bacteremia,
Guillain-Barre,
reactive arthritis
Campylobacter fetus:
clinical manifestations (4)
(1) diarrhea
(2) bacteremia
(3) vasc infections
(4) CNS infections
Helicobacter pylori

Characteristics:
(1) enzyme production
(2) motility
(3) virulence factors + role
(1) urease: urea -> NH3
(2) corkscrew motion
(3) CagA = gastric cancer
VacA = immunosuppressive
Helicobacter pylori:
clinical manifestations (7)
(1) chronic active gastritis
(2) pangastritis = gastric cancer/ulcers, less acid
(3) antral gastritis = duodenal ulcers, more acid
(4) peptic ulcer disease (cag+)
(5) gastric ulcers
(6) gastric cancer
(7) MALT tumor
Helicobacter pylori

Treatment:
(1) diagnosis
(2) don't treat which pts?
(3) drugs
(1) endoscopy, urea breath test
(2) children, non-ulcer, asymptomatic
(3) acid suppressant + antibiotic