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21 Cards in this Set
- Front
- Back
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what are the pathogenic mechanisms of Neisseria meningitidis?
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pili, polysaccharide capsule, ENDOtoxin
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pathogenic mechanisms of N. gonorrhoeae
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pili, endotoxin, IgA protease
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N. meningitidis commonly causes..
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Epidemic Meningitis
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Humans carry N. meningitidis via what route?
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nasopharyngeal carriage
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True or False: gonorrhea is usually symptomatic in most males
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False (aymptomatic in most males)
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O antigen of LPS serves what function?
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facilitate adherence to human tissues
resistance to phagocytes protection from antibodies soluble carrier for lipid A basis for serotyping |
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Characteristics of Neisseriaceae?
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gram negative diplococci
distinct kidney bean shape pyogenic (pus-producing) DO NOT produce EXOtoxins disease due to ability to resist phagocytosis |
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T or F: Endotoxin can be found in all gram positive bacteria
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False
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Members of Enterobacteriaceae?
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E. coli
Shigella Salmonella |
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Characteristics of E. coli?
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Falculative gram negative rods
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E. coli is the major cause of meningitis in whom?
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Newborns
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Virulence factors of E. coli:
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ENTEROtoxins
pili antiphagocytic capsule hemolysin (lyses red blood cells) ability to obtain iron from transferrin |
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4 classes of E. coli that cause gastroenteritis in humans?
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Enterotoxigenic E. coli
Enterohemolytic Enteropathogenic Enteroinvasive |
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Enteropathogenic E. coli (EPEC) is known to cause what type of diarrhea?
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Infantile Diarrhea (in newborns and young children, may result in death)
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Enterotoxigenic E. coli (ETEC) commonly causes which type of diarrhea?
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Traveler's Diarrhea
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Which types of E.coli produce a Shiga-like toxin?
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EHEC and EIEC
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Key virulence factor of EIEC?
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plasmid-encoded ability to invade epithelial cells lining the intestine
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T or F: E. coli are the most common cause of urinary tract infections?
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True
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EIEC produces a disease that is indistinguishable from the disease produced by Shigella, which disease?
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Bacillary dysentary
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Shigella's multiple antibiotic resistance is mostly due to what?
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Organisms ability to acquire plasmids
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In what ways is Shigella and Enteroinvasive E. coli similar?
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both produce a Shiga toxin (or shiga-like; EIEC)
both have same mechanism for invasion of intestinal epithelium (causes severe local inflammation response which results in bloody diarrhea) |
