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4 Cards in this Set
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What are some of the new drugs for Gout ? (2010)
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Patients and prescribers are seeing lots of ads for new gout drugs...Uloric, Colcrys, and now Krystexxa.
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How do you best titrate Allopurinol?
To Serum uric acid of ____? Max Dose of Allopurinol with good renal function ? |
Allopurinol is usually the first choice to lower uric acid...but prescribers often don't give a high enough dose.
Suggest starting with allopurinol 100 mg/day and titrating to a serum uric acid less than 6 mg/dL. Explain that it's okay to go up to 800 mg/day in patients with good renal function. |
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How does Uloric work?
What is the generic name ? |
Uloric is a xanthine oxidase inhibitor...like allopurinol.
febuxostat |
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Is Uloric better for renal insufficiency?
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Reps will say that Uloric (febuxostat) doses don't need to be adjusted for renal impairment. But keep in mind that allopurinol doesn't either...until creatinine clearance is 20 mL/min or less.
Reps will also say that Uloric lowers uric acid more than allopurinol...but this is compared to just 300 mg/day of allopurinol. |
