Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
22 Cards in this Set
- Front
- Back
|
Connective tissue consists of:
|
1. Specific Cells
2. Extracellular matrix |
|
|
Fxns of Connective tissue
|
1. Bind/Interconnect
ligaments/tenonds 2. Support and nourishment 3. Compartmentalization 4. Protection 5. Storage |
|
|
Relationship b/w Epithelial and connective:
|
1. Parenchyma: carry out main fxn
2. Supporting(Stroma): connective tissue, extracellular matrix |
|
|
Pancreas:
Parenchyma? Stroma? |
Parenchyma = epithelial gland cells
Stroma= basement membrane |
|
|
Connective Tissue Proper Types:
|
1. Loose Connective Tissue
2. Dense Connective Tissue regular/irregular |
|
|
Specialized Connective Tissue types:
|
1. bone, cartilage, blood, adipose, lymphatics...
|
|
|
Components of Connective Tissue:
|
1. ECM
2. Specific Cells |
|
|
ECM types:
|
1. Fibers
collagen, reticular, elastic 2. Ground substance |
|
|
Collagen Fibers:
Appearance: Composition: |
wavy bands, stains with eosin
triple polypeptide helix+glycoprotein made via fibroblasts |
|
|
Reticular Fibers
Appearance Composition |
thin, thread-like loose CT
Type 3 collagen+glycoprotein Produced via fibroblasts |
|
|
Elastic Fibers
Appearance: Fxn: Production: Composition: |
thin brnaching, irregular, interwoven with collagen
stretchable produced via fibroblast or smooth muscle cells Elastin: globular protein Microfibrils |
|
|
Ground Substance:
texture? Compositon? Fxn? |
1. amorphous, viscous
2. proteoglycans, gags, adhesive glycoproteins 3. resist compressive forces |
|
|
GAGs:
Structure Charge Examples |
Large unbranched polysaccharide chains with repeating disaccharide units
negatively charged Ex: heparin, keratan sulfate, hyaluronic acid |
|
|
Proteoglycans structure
Glycoprotein examples |
Core protein + GAG
fibronectin, laminin |
|
|
Properties Ground substance
|
1. Negatively charged-->Na+ -->increase h20-->suck in h20
2. Gel Properties-->filtration, diffusion, defense |
|
|
Fxns of Ground Substance
|
1. Lubrication
2. Modulates cell-cell signaling Binds factors-slow release or activation: a. Fibrobloast growth factor +hep. sulfate b. Transforming growth factor beta activites c. reuglates protease activity 3. Modulates/affects epithelial cell differentiation and fxn |
|
|
Cells which inhabit CT
|
Fibroblasts
Macrophages Mast Cells Adipose Cells Blood Cells(RBC/WBC) Dendritic Cells |
|
|
Fibroblost characeteristics
|
1. Elongated Spingly
2. Most permanent resident of ECM 3. Synthesize CT fibers and ECM 4. Seceret factors 5. Would healting |
|
|
Macrophage characteristics
|
1. Derived from blood monocytes
2. Reside tissue 3. host defense 4. love to eat 5. Secrete factors and cytokines 6. Relatives: alveolar, pleural pritoneal, osteoclasts |
|
|
Mast Cells characteristics
|
1. Gradnules: histamine, heparin
2. Defense 3. Pathology: allergy 4. degranulate with IgE |
|
|
Hemopoietic Cells
|
1. RBC/WBCs
2. Lymphocytes B/T cells 3. Neutrophils 4. Eosinophils 5. Basophils 6. Natural Killers |
|
|
Adipose Cells
|
1. Fat storage
2. cytoplasm is clear 3. small nucleus on side |
