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10 Cards in this Set

  • Front
  • Back
  • 3rd side (hint)
Step 1 (control point)
Glucose ---> Glucose-6-phosphate (G6P)
ATP-->ADP
Hexokinase

phosphorylation
Step 2
(mass action)
Glucose-6-phosphate ---> Fructose-6-phosphate (F6P)
Phosphoglucose isomerase (PGI)

isomerization
Step 3
(control point)
Fructose-6-phosphate ---> Fructose-1,6-bisphosphate (FBP)
ATP --> ADP
Phosphofructokinase (PFK)
phosphorylation
Step 4
(mass action)
Fructose-1,6-biphosphate (FBP) ---> Glyceraldehyde-3-phosphate (GAP) + Dihydroxyacetone phosphate (DHAP)
Aldolase
cleavage
Step 5
(mass action)
Dihydroxyacetone phosphate (DHAP) ---> Glyceraldehyde-3-phosphate (GAP)
triose phosphate isomerase (TIM)

Step 6
(mass action)
Glyceraldehyde-3-phosphate (GAP) ---> 1,3-Bisphosphoglycerate (1,3-BPG)
NAD+ --> NADH
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

Generation of high energy compound
Step 7
(mass action)
1,3-Bisphosphoglycerate (1,3-BPG) ---> 3-Phosphoglycerate (3PG)
ADP --> ATP
phosphoglycerate kinase (PGK)

substrate-level phosphorylation
Step 8
(mass action)
3-Phosphoglycerate (3PG) --> 2-phosphoglycerate (2PG)
phosphoglycerate mutase (PGM)

rearrangement
Step 9
(mass action)
2-phosphoglycerate (2PG) --> Phosphoenolpyruvate (PEP)
enolase

High energy compound
Step 10
(control point)
Phosphoenolpyruvate (PEP) ---> Pyruvate
ADP --> ATP
pyruvate kinase

Substrate-level phosporylation