Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
7 Cards in this Set
- Front
- Back
|
Glyceryl Trinitrate- Presentation
|
0.6mg tablets 50mg transdermal patch (0.4mg/hr release) |
|
|
Glyceryl Trinitrate- Pharmacology
|
Vascular smooth muscle relaxant. Reduces preload by causing venous dilatation promoting venous pooling and reducing venous return. Reduces afterload by causing arterial dilatation reducing systemic vascular resistance and arterial pressure |
|
|
Glyceryl Trinitrate- Pharmacology (cont.)
|
Reduces myocardial O2 demand Reduces systolic, diastolic and MAP, whilst maintaining coronary artery perfusion Mild collateral coronary arterial dilatation which may improve blood supply to ischaemic areas of myocardium Mild tachycardia 2ndary to slight fall in BP Preterm labour= uterine quiescence |
|
|
Glyceryl Trinitrate- Indications
|
Chest pain with ACS Acute LVF Hypertension associated with ACS (MICA) Autonomic dysreflexia Preterm labour (consult only) |
|
|
Glyceryl Trinitrate- Contraindications
|
Known hypersensitivity Systolic BP <110mmHg (tablet) <90 (patch) Viagra/ Levitra in last 24hrs, Cialis in last 4 days HR > 150bpm, <50bpm (excluding autonomic dysreflexia) VT Inferior STEMI with BP <160mmHg Right Ventricular infarct |
|
|
Glyceryl Trinitrate- Precautions
|
Concurrent use with other tocolytics Recent AMI Elderly patients No previous administration |
|
|
Glyceryl Trinitrate- Side effects
|
Tachycardia Skin flushing Hypotension Bradycardia Headache |
