Glucagon

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Class

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ANTI-hypoglycemic(hromone)

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Action (1-2)

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1. a pancreatic hormone that stimulate the breakdown of glycogen in the liver to glucose
2.inhibits the converson of circulating glucose to glycogen

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Action (3-5)

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3. Indirectly raises blod glucose levels
4.Stimulates the release of catecholamines
5.Onset is within 5-20.peakin30

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SIDE EFFECTS

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CNS: dizziness; lightheadedness
Cardio: HTN;HypoT; Tachycardia
GI: Nausea; Vomiting
Other: alergic reaction-urticaria

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CONTRAindications

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Absolute: hypersensitivity to proteins
Relative: Alcoholics or malnourished PT's

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PRECAUTIONS

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DONT MIX WITH SALINE
Use wih caution in pt's with cardio or renal disease
BS levels should be taken prior

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Drug Interactions

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A precipitate will form if glucagon is mixed wiht chloride solutions
Hyperglycemic effect can be ^ and prolonged if used with EPI.

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PREPARATIONS

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1mg of white powder in vial #2 & 1ml of fluid diluent in cial #1
note: reconstitue only with diluent provided

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Adult dose

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Hypoglycemis: 1mg; may repeat q20min. for a total of 3 doses
B blocker: 1mgmay rpt. q20min prn

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PEDIATRIC DOSE

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Hypoglycemis: 0.03mg/kg
B Blocker: 0.25mg'kg to a max of 1 unit
note:rarely used in the Out of hosp. setting

Front 11

ROUTE

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I.M.