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13 Cards in this Set
- Front
- Back
what's GLP agonist ??
|
glucagon-like peptide 1 agonist
like endogenous but resist DPP-4 breakdown so ,longer half life |
|
route
|
subcut
|
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benefits 2
|
1-glucose-lowering agent
2-improve satiety/wt loss |
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forms/types X2
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1-Exena-tide
2-Lira-glutide |
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Exena-tide/dose
|
5 micg
10 micg twice daily- before meals |
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Exena-tide /extended release
|
2 mg
once weekly / extended release |
|
Exena-tide
expected HbA1c lowering |
0.6-1.2 %
|
|
Exena-tide
expected average wt reduction |
4 kg
|
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Exena-tide
side effects |
-pancreatitis
-acute |
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Exena-tide
trade name |
|
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Lira-glutide
trade name |
|
|
Lira-glutide
dose |
0.6/1.2/1.8
once daily anytime |
|
Lira-glutide
|
nausea/vomitting
dizziness/headach increased calcitonin/medullary thyroid CA in (rodent) |