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20 Cards in this Set

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True/False. The symptoms of acute hepatitis and biliary obstruction can be quite similar with lots of overlap between them.
True
Is pain associated with biliary obstruction?
Yes, it can be.
Is pain associated with acute hepatitis?
Yes, there can be, but it can also be asymptomatic
Where would one expect to find the pain in someone with biliary obstruction?
Right upper quadrant or epigastrium
If pain were to present with acute hepatitis, where would you expect to see it?
Right upper quadrant
Where does referred pain from the liver or biliary tract occur?
The back and right scapular and shoulder
A patient presents with a sudden onset, severe, constant pain that lasted about an hour. Would this be more indicative of Acute Hepatitis or Biliary Obstruction?
Biliary Obstruction – the pain can be very severe lasting from 30 minutes to 5 hours with stones...longer would imply acute cholecystitis (Harrison).
Is there always pain associated with biliary obstruction?
No. If gradual obstruction of the CBD (common bile duct) over weeks or months (by narrowing), often no pain is associated with jaundice.
What is the difference between a sign and a symptom?
Sign = something that is observed
Symptom = something the patient reports to you
What are some common “symptoms” that could be associated with both acute hepatitis AND biliary obstruction?
abdominal pain/discomfort, nausea, chills, and general malaise (note: in some cases they could also be asymptomatic)
What are some common signs of biliary obstruction?
Jaundice, fever, RUQ pain
What clinical presentation generally precedes the onset of jaundice in acute viral hepatitis?
“flu-like” symptoms of malaise, fatigue, anorexia, nausea, vomiting, myalgia, and headache. These generally occur 1-2 weeks before the onset of jaundice.
What “signs” might be found on examination of a patient with acute hepatitis?
There may be jaundice, low-grade fever, tender and enlarged liver, possible splenomegaly. (note: can be asymptomatic)
A patient presents to the office with jaundice and a constant, mild abdominal discomfort in the upper right quadrant. Is this more indicative of Acute Hepatitis or Biliary Obstruction?
Acute Hepatitis would be higher on the differential due to mild nature of pain, but it could still be biliary obstruction so further testing required. Note: there is not always pain associated with acute hepatitis.
What are some causes of acute hepatitis?
Viral infection, alcohol, toxins, drugs, autoimmune
What is the main symptom that can be used to help differentiate between acute hepatitis and biliary obstruction?
The type and nature of pain described by the patient.
List some causes of biliary obstruction.
Common duct stones (choledocholithiasis), acute cholangitis (primary sclerosing cholangitis), biliary strictures, infection, biliary neoplasms.
The classic signs/symptoms of biliary obstruction are termed “charcot’s triad”. What 3 sign’s/symptoms does this include?
abdominal pain, jaundice, and fever
How could one definitively differentiate between acute hepatitis and biliary obstruction?
ERCP (endoscopic retrograde cholangiopancreatography) or MRCP (magnetic resonance cholangiopancreatopgraphy)
If low grade fever occurs with a patient suspected to have acute viral hepatitis, which strains would be suspected? (A,B,C,D,E)
Hepatitis A or E. Rarely Hep B is associated with fever