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34 Cards in this Set
- Front
- Back
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Most serous salivary secretion?
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Parotid
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Most mucinous salivary secretion?
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Sublingual
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What begins starch digestion?
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Alpha-amylase
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What lubricates food?
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Mucins (glycoproteins)
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Intrinsic factor. Source?
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Parietal Cells
Stomach |
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Gastric acid. Source?
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Parietal Cells
Stomach |
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Pepsin
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Chief Cells
Stomach |
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HCO3-
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Mucosal Cells Stomach
Duodenum |
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Regulation of gastric acid?
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-Increased by histamine, ACh, gastrin
-Decreased by somatostatin, GIP, prostaglandin, secretin |
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Regulation of pepsin?
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-Incr by vagal stimulation, local acid
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What regulated HCO3-?
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Increased by secretin.
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Gastrin. Source?
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G cells
Antrum of Stomach |
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CCK. Source?
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I cells
Duodenum Jejunum |
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Secretin. Source?
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S cells
Duodenum |
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Somatostatin. Source?
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D cells
Pancreatic islets GI mucosa |
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GIP. Souce?
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K cells
Duodenum Jejunum |
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VIP. Source?
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PS ganglia in sphincters, gall bladder, small intestine
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Gastrin. Action?
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Increase:
gastric H+ secretion growth of gastric mucosa gastric motility |
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CCK. Action?
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Increase:
pancreatic secretion GB contraction Decrease: Gastric emptying |
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Secretin. Action?
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Increase:
Pancreatic HCO3- Decrease gastric acid secretion |
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Somatostatin. Action?
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Decreases everything!
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GIP. Action?
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Exocrine:
Decr gastric acid secretion Endocrine: Incr insulin release |
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VIP. Action?
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Increase intestinal water and electrolyte secretion.
Increase relaxation of smooth muscle and sphincters |
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NO. Action?
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Increase smooth muscle relaxation including LES.
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Gastrin. Regulation?
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Incr by stomach distension, amino acids, peptides, vagal stimulation.
Decr by stomach pH<1.5 |
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CCK. Regulation?
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Decr. by secretin and stomach pH < 1.5
Incr by Fatty acids, amino acids |
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Secretin. Regulation?
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Incr by acid, FA's in lumen of duodenum
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Somatostatin. Regulation?
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Incr by acid
Decr by vagal stimulation |
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GIP. Regulation?
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Incr by FA's, AA's, oral glucose
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VIP. Regulation?
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Incr by distension and vagal stimulation.
Decr by adrenergic input. |
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What hormone is increased in ZE Syndrome?
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Gastrin
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What are potent stimulators of Gastrin?
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Phe and Tryp
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What is used to treat VIPoma and carcinoid tumors?
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Somatostatin
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What is VIPoma?
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Non-alpha, non-beta islet cell pancreatic tumor that secretes VIP. Copius diarrhea.
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