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24 Cards in this Set

  • Front
  • Back
Difference between segmenting contraction and MMC?
SC: stretch receptors in stomach and stimulate parasympathetic in small/large intestine
MMC: from stomach to large intestine. replaces SC during fasting or most food is absorbed
diff between segmenting contraction and peristalsis?
SC=in small and large intestine, but peristalsis is in oesophagus AS WELL.
SC is BOTH directions (better mixing in intestine), peristalsis is ONE direction
What is haustration?
mixing of feces to expose it to the surface of large intestine to absorb water
how many simultaneous contractions of caecum and sigmoid colon occur per day? what is it called?
about 5 --> called mass movement
What are the 2 plexuses of enteric nervous system?
myenteric: between circular and longitudinal layers
submucosal: in submocosa
Their functions?
Myeneteric: motility
submucosal: secretion, absorption, blood flow
How do we achieve relaxation of sphincter?
ANS: parasympathetic
enteric: myenteric plexus (by NO)
when is colon enlarged (related to sphincter)?
when sphincter is closed (sympathetic- activates circular smooth muscle)
What does internal anal sphincter and rectum do during defecation reflex?
IAS: relax and open, forcing out the feces
rectum: contracts
what stimulates the reflex?
distension of rectal wall which activate its stretch receptors --> reflex
What is Hirchsprung's disease?
enlarged colon due to lack of para and myenteric nerves
Components of saliva?
H2O, ions, salivary amylase, mucin, immunoglobulin
Pathway of salivation activation (para)?
High centre --> salivary nucleus of medullar --> salivary gland
More salivation during sleep. true or false?
false
Why is stomach content acidic?
To break down cellulose, activate enzymes and sterilize food
What are the 4 types of cells in stomach?
Mucous, Parietal, Chief, Enteroendocrine
Where does HCl come from in parietal cells?
CO2 and H2O turn into H+ and HCO3-
HCO3- is exchanged with CL- which then leaves with H+ into the duct (exchanging with K+ here)
What are the 3 phases of gastric acid secretion?
cephalic, gastric, intestinal (intestinal being sympathetic and inhibiting)
What is the stimulus? and which cells do they activate?
Distension + Ach and gastrin --> parietal cells and G cells
which phase has decreased Ach and gastrin?
intestinal phase
What does pancreas secret (form exocrine)?
alkaline fluid (HCO3-) to neutralise acidic pH and activate enzymes
AND enzymes
What stimulates secretion of acidic and enzyme-rich juice from pancreas?
Duodenum produce secretin and CCK when chyme reaches duodenum
secretin --> HCO3-
CCK --> enzymes
What helps in trypsinogen --> trypsin?
enterokinase (brush border enzymes)
now trypsin can break proteins into peptides
how doe secretin regulate pH?
It can inhibit gastric acid secretion from parietal cells in stomach, AND stimulate bicarbonate secretion from pancreas.