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19 Cards in this Set

  • Front
  • Back
Gastrin
Secreted in response to neural impulses concerning food--G cells are stimulated by enteric interneurons--
Secretin
Secreted by: S cells(duodenum)
Functions: Increase pancreatic secretions rich in BICARB from pancreatic duct cells, Increase BILE secretions, and increase HCO3 and water production by the liver
Stimuli for Secretion: H+ or fatty acids in the duodenal lumen
CCK
Secreted by: I cells(duodenum and jejunum)
Function: HOMOLOGOUS TO GASTRIN, Stimulates GALLBLADDER CONTRACTIONS and relaxation of the sphincter of Oddi to promote bile release, stimulates pancreatic enzyme secretion, INHIBITS gastric emptying
Stimuli for Secretion: Fatty acids(not TG's)
GIP
Secreted by: K cells in the duodenum/jejunum
Stimuli for Secretion: Glucose, AA's, FA's
Function: Increases insulin secretion, decreases gastric acid production, and may inhibit gastric motility
Motilin
Secreted by: M cells throughout the GI tract(NOT the same M cells that antigenic present)
Stimuli for Secretion: ?
Function: Stimulates migrating myoelectric complexes
Ghrelin
Hunger hormone
What is the gastrin receptor? Why is this significant?
CCK-B receptor. B stands for brain--similarity to CCK A
NO
Secreted by:
Responds to:
Function:
Enkephalins
Secreted by:
Responds to:
Function: only one to inhibit GI secretion
GRP
Secreted by:
Responds to:
Function: stimulates release of gastrin from G cells
VIP
Secreted by:
Responds to:
Function:
Substance P
Secreted by:
Responds to:
Function:
Is saliva iso, hypo, or hypertonic to plasma?
Hypotonic
How is saliva essentially secreted?
Chlorine is built up in the acinar cells and secreted in response to food or hunger and sodium follows it and water follows that
Saliva is hypotonic, alkaline, and has a fair amount of bicarbonate.
Saliva is hypotonic, alkaline, and has a fair amount of bicarbonate.
How is salivary release regulated?
EXCLUSIVELY BY NERVES--neurotransmitters are norepi and epi; ACh, NEpi, SP
What nerve innervates the parotid gland?
Cranial nerve 9
What is the prime function of secretin?
To reduce the amount of acid present in the duodenal lumen via contol of gastric secretion and buffering with bicarb--MAIN JOB IS INCREASE IN BICARB
What are some additional effects of secretin?
Stimulates pepsinogen release, decreases acid secretions, and is TROPHIC for the pancreas