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44 Cards in this Set
- Front
- Back
Secretin is released where?
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duodenum
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What stimulates secretin release?
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low pH
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What inhibits secretin release?
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high pH
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Where does secretin go?
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paracrine- pancreas and gallbladder
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What does secretin stimulate?
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production and release of bicarb from the pancreas and gallbladder
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What is the second messenger for secretin?
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cAMP
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Where is CCK secreted from?
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duodenum
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What stimulates CCK release?
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food, especially fats
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What inhibits CCK release?
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high pH
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Where does CCK go?
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pancreas and gallbaldder
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What does CCk do?
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primarily fat and protein digestion
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What is the second messenger for CCK?
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IP3/DAG
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Where is GIP secreted?
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duodenum
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What stimulates GIP release?
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glucose
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What inhibits GIP release?
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high pH
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Where goes GIP go?
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pancreatic islet cells
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What does GIP do?
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enhances insulin secretion
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What is the second messenger for GIP?
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cGMP
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Where is somatostatin released?
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duodenum
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What stimulates the release of somatostatin?
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duodenal hormones
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Where does somatostatin go?
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paracrine
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What is the function of somatostatin?
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purely inhibitory
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What is the second messenger for somatostatin?
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cAMP
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Where is VIP secreted?
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duodenum- Auerbachs plexus
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What stimulates the release of VIP?
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duodenal hormones
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What inhibits VIP?
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high pH
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What is the function of VIP?
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purely inhibitory to all duodenal hormones
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What is the second messenger of VIP?
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cAMP
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What kind of diarrhea does a VIPoma give?
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watery or secretory- only one that can give both!
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How can you tell the difference between watery or secretory diarrhea?
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D-xylose test
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If there is D-xylose in the urine, what kind of diarrhea is it?
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secretory
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if there is no D-xylose in the urine, what kind of diarrhea is it?
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inflammatory diarrhea
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Where is gastrin secreted?
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from the antrum of the stomach
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What stimulates the release of gastrin?
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high pH
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What inhibits the release of gastrin?
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low pH
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Where does gastrin go?
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parietal cells of the stomach- mostly in the body
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What is the function of gastrin?
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stimulates the production of HCL and intrinsic factor
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What is the second messenger of gastrin?
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calcium
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Where is ANP released from?
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right atrium
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What stimulates the release of ANP?
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high volume (stretch of right atrium)
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What inhibits the release of ANP?
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low volume
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Where does ANP go?
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kidney
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What does ANP do in the kidney?
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dilates the afferent renal artery, inhibits aldosterone
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What is the second messenger for ANP?
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NO
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