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44 Cards in this Set

  • Front
  • Back
Secretin is released where?
duodenum
What stimulates secretin release?
low pH
What inhibits secretin release?
high pH
Where does secretin go?
paracrine- pancreas and gallbladder
What does secretin stimulate?
production and release of bicarb from the pancreas and gallbladder
What is the second messenger for secretin?
cAMP
Where is CCK secreted from?
duodenum
What stimulates CCK release?
food, especially fats
What inhibits CCK release?
high pH
Where does CCK go?
pancreas and gallbaldder
What does CCk do?
primarily fat and protein digestion
What is the second messenger for CCK?
IP3/DAG
Where is GIP secreted?
duodenum
What stimulates GIP release?
glucose
What inhibits GIP release?
high pH
Where goes GIP go?
pancreatic islet cells
What does GIP do?
enhances insulin secretion
What is the second messenger for GIP?
cGMP
Where is somatostatin released?
duodenum
What stimulates the release of somatostatin?
duodenal hormones
Where does somatostatin go?
paracrine
What is the function of somatostatin?
purely inhibitory
What is the second messenger for somatostatin?
cAMP
Where is VIP secreted?
duodenum- Auerbachs plexus
What stimulates the release of VIP?
duodenal hormones
What inhibits VIP?
high pH
What is the function of VIP?
purely inhibitory to all duodenal hormones
What is the second messenger of VIP?
cAMP
What kind of diarrhea does a VIPoma give?
watery or secretory- only one that can give both!
How can you tell the difference between watery or secretory diarrhea?
D-xylose test
If there is D-xylose in the urine, what kind of diarrhea is it?
secretory
if there is no D-xylose in the urine, what kind of diarrhea is it?
inflammatory diarrhea
Where is gastrin secreted?
from the antrum of the stomach
What stimulates the release of gastrin?
high pH
What inhibits the release of gastrin?
low pH
Where does gastrin go?
parietal cells of the stomach- mostly in the body
What is the function of gastrin?
stimulates the production of HCL and intrinsic factor
What is the second messenger of gastrin?
calcium
Where is ANP released from?
right atrium
What stimulates the release of ANP?
high volume (stretch of right atrium)
What inhibits the release of ANP?
low volume
Where does ANP go?
kidney
What does ANP do in the kidney?
dilates the afferent renal artery, inhibits aldosterone
What is the second messenger for ANP?
NO