Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
56 Cards in this Set
- Front
- Back
|
Proton pump inhibitors |
Irreversibly inactivate Na/K ATPase pump End with "prazole" |
|
|
Lansoprazole |
Proton pump inhibitor |
|
|
Omeprazole |
Proton pump inhibitor |
|
|
pantoprazole |
Proton pump inhibitor |
|
|
Esomeprazole |
Proton pump inhibitor |
|
|
Rabeprazole |
Proton pump inhibitor |
|
|
Antacids |
reduce the acid load of the stomach 1. neutralize the stomach acid 2. form a protective layer to prevent reflux |
|
|
H2 receptor antagonists |
Competitively block the H2 receptors on the parietal cells reducing gastric acid secretions. This competes with histamine decreasing the cAMP in the parietal cells End with "tidine" |
|
|
Cimetidine |
H2 receptor antagonist |
|
|
Faomitidine |
H2 receptor antagonist |
|
|
Nizatidine |
H2 receptor antagonist |
|
|
Ranitidine |
H2 receptor antagonist |
|
|
Mucosal strengtheners |
Form a protective barrier at the ulcer site that is resistant to acid, pepsin and bile |
|
|
Sucralfate |
Mucosal strengthener |
|
|
PGE1 analogues |
Binds to the PGE2 receptor which protects the stomach mucosa by increasing the secretions of mucus and bicarbonate |
|
|
Misoprostol |
PGE1 analogue |
|
|
5-HT3 antagonists |
Central and peripheral block the serotonin 5-HT3 receptor. Preventing serotonin from triggering an emetic response End with "setron" |
|
|
Dolasetron |
5-HT3 antagonists Anti-emetic |
|
|
Ondansetron |
5-HT3 antagonists Anti-emetic |
|
|
Tropisetron |
5-HT3 antagonists Anti-emetic |
|
|
Granisetron |
5-HT3 antagonists Anti-emetic |
|
|
Palonosetron |
5-HT3 antagonists Anti-emetic |
|
|
D2 antagonists |
selectively block the chemo-receptor trigger zone. To a lesser extent the vomit center of the brain |
|
|
Domperidone |
D2 (Dopamine) antagonists Anti-emetic |
|
|
Droperidol |
D2 (Dopamine) antagonists Anti-emetic |
|
|
Haloperidol |
D2 (Dopamine) antagonists Anti-emetic |
|
|
Metocloperamide |
D2 (Dopamine) antagonists also has secondary action by blocking the 5-HT3 receptors Anti-emetic |
|
|
Prochlorperazine |
D2 (Dopamine) antagonists Anti-emetic |
|
|
Oral rehydration therapy |
Aims to replace electrolytes, glucose, fluids and salts lost through diarrhea |
|
|
Opioids (diarrhea) |
Activate the mu receptor causing decreased GI motility and secretions. With some possible 5-HT receptor action. |
|
|
Codeine |
Opioids (diarrhea) |
|
|
Diphenoxylate |
Opioids (diarrhea) |
|
|
Loperamide |
Opioids (diarrhea) |
|
|
Stool softeners |
Softens the stool by assisting the mixture of water into the stool. May also increase fluid secreations. |
|
|
Docusate |
Stool softeners (detergent) constipation |
|
|
Poloxamer |
Stool softeners (detergent) constipation |
|
|
liquid Paraffin |
Stool softeners (lubricant) constipation |
|
|
Stimulant laxative |
Act by direct stimulation of nerve endings in the colonic mucosa increasing GI motility. May also cause accumulation of water and electrolytes in the colonic lumen |
|
|
Bisacodyl |
Stimulant laxative constipation |
|
|
Sodium picosulfate |
Stimulant laxative constipation |
|
|
Senna |
Stimulant laxative constipation |
|
|
Osmotic laxatives |
Cause local peristaltic stimulation Draws water into the stool, softening |
|
|
Lactulose |
Osmotic laxatives constipation |
|
|
Mannitol |
Osmotic laxatives constipation |
|
|
Sorbitol |
Osmotic laxatives constipation |
|
|
Glycerol |
Osmotic laxatives constipation |
|
|
Hyoscine Butylbromide |
Anticholinergic smooth muscle relaxant Irritable Bowel Syndrome |
|
|
Alverine |
Antispasmotics Irritable Bowel Syndrome |
|
|
Mebeverine |
Antispasmotics Irritable Bowel Syndrome |
|
|
Peppermint Oil |
Antispasmotics Irritable Bowel Syndrome |
|
|
Antispasmotics |
Block the release of Ca and stops contractions of the gut, relaxation of the GI |
|
|
5-Aminosalicylic acids |
Inflammatory Bowel Disease decrease prostaglandin synthesis decrease migration of of inflammatory cells by scavenging for superoxides zine/zide |
|
|
Mesalazine |
5-Aminosalicylic acids Inflammatory Bowel Disease zine/zide |
|
|
Olsalazine |
5-Aminosalicylic acids Inflammatory Bowel Disease zine/zide |
|
|
Sulfasalazine |
5-Aminosalicylic acids Inflammatory Bowel Disease zine/zide |
|
|
Balsalazide |
5-Aminosalicylic acids Inflammatory Bowel Disease zine/zide |
