Gi - Bacterial Diarrhea

Front 1

What is invasive GE?

What cells are present in feces?

S/S of invasive bacteria?

Back 1

invasion past epithelial layer

leukocytes

dysentery, blood in stool, fever

Front 2

G- rods, motile facultative anaerobes, non-lactose fermenting
("I don't want milk with my turtles")

common transmission:

Back 2

Salmonella

animal-human (turtles, iguanas)
food, more common in summer

Front 3

Which salmonella antigen:
assoc. with LPS?

flagella?

capsule?

Sensitive to gastric acid or not?

Back 3

O

H

Vi

Yes - normally need large number to invade

Front 4

Salmonella infections often result in what symptoms?

What species of Salmonella cause enteric fever? (typhoid)

Unique about their pathology?

Back 4

fever, abd pain, diarrhea

typhi, paratyphi

cause little intestinal damage, mostly in bloodstream

Front 5

most common form of salmonellosis?

How long do symptoms last?

What cells engulf S. typhi bacteria?

Back 5

enteritis

start p 6-48 hrs, last 2 d-1 wk.

macrophages

Front 6

Salmonella dx:

lactose fermenter?

motile or not?

H2S + or -?

McConkey agar - clear or pink?

Back 6

non-lactose (no milk!)

motile

H2S+

clear on McConkey - no lactose fermentation

Front 7

G-, *non-motile*, non-lactose fermenting, produce Shiga toxin:

closely related to what bacteria?

How many bacteria can cause disease?

Back 7

Shigella

E. Coli

10-20 - FEW NUMBERS CAUSE INFECTION

Front 8

Shigella transmission? (4 F's)

How is Shigella different from Salmonella?

S/S?

Back 8

food, fingers, feces, flies

non-motile, H2S-, fecal WBC's

fever, abd pain, watery diarrhea, dysentery

Front 9

G-, slender, curved/comma shaped (remeber the C's), microaerophilic, motile:

Transmission?

Where can they survive in humans?

Back 9

Campylobacter

fecal-oral, intestinal tract of animals

intracellularly inside monocytes, intestinal epithelial cells

Front 10

Campylobacter is the leading cause of ____________ in the U.S.

Virulence factors?

What condition can Yersinia imitate?

Back 10

bacterial diarrhea

flagella, adherence factors, heat-labile toxins, Shiga toxin

appendicitis

Front 11

aerobic G- bacilli, lives in farm animals, transmitted fecal-oral:

causes enlargment of ____________.

What time of year is Yersinia usually transmitted? Why?

Back 11

Yersinia enterocolitica

mesenteric lymph nodes

winter - Yersinia can survive cold temps (fridge isn't safe)

Front 12

small curved G- rods with a *single flagellum*:

produces cholera toxin, activates cAMP pathway:

tranmission?

Classic S/S of cholera?

Back 12

Vibrio species

V. cholerae

bad H20, food

profuse, severe watery, "rice-water" diarrhea, fluid loss

Front 13

What type culture needed for V. cholerae?

What strains of V. haemolyticus are most virulent?

what strains grow in marine environments?

Back 13

TCBS agar

hemolytic - enterotoxin produced

halophilic - no more sushi!