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31 Cards in this Set

  • Front
  • Back
Cells in vagina and cervix.
Prepubescent and Puberty.
Prepubescent: squamous
Puberty: Columnar
Normal Flora in urethra.
Staphylococci
Corynebacterium
Anaerobes
NH Strep
Normal Flora in Vagina.
Prepubescent & Postmenopausal.
Increased Staph, Strep, coliforms
Normal Flora in Vagina.
Reproductive years.
Decreased Staph
Increased Lactobacilli, Strep
Low # of coliforms
Most common Non-gonococcal urethritis.
Chlamydia
Bacterial Vaginosis.
What are the indications?
Fishy smelling odour
clue cells covered with bacteria
alkaline pH in vagina
increased mobiluncus, Gardnerella vaginalis
Watery non-inflammatory exudates
What are the symptoms of Candida albicans?
and what disease does it cause?
thick, cheesy discharge
itchy

Vaginitis
What are the symptoms of Trichomonas vaginalis infection?
yellow-green discharge, profuse
itchy
Vaginal Swab, what we look for?
Yeast
BV
Cervical Swab, what we look for?
GC

Chlamydia trachomatis
Vag-Rectal Swab, what we look for?
Group B Strep
What are the symptoms of GC in male and females?
Male: urethritis, dysuria, purulent discharge

Female:
20% symptoms of urethritis
80% painful intercourse, lower abd pain, irreg bleeding
What disease conditions does Chlamydia trachomatis cause in neonates?
neonatal pneumonia

neonatal conjunctivitis
Drug of choice for GC
Ceftriazone (IM)
Ciprofloxacin
Cefixime (oral)
Tetracycline, Doxycycline
Drug of choice for Chlamydia trachomatis.
Tetracycline
Erythromycin
Drug of choice for Trachomonas vaginalis.
Flagyll (metronidazole)
Drug of choice for Haemophilus ducreyi.
Erythromycin
Ceftriazone
Ciprofloxacin
Drug of choice for Treponema pallidum (syphillus)
Penicillin
Drug of choice for HSV (genital herpes) and HPV (genital warts).
Sorry. No cure >_<
Drug of choice for Group B strep.
Penicillin

If allergic -> erythromycin or clindamycin
Selective media for isolation of GC.
ML or TM and/or CHOC
5% CO2
24-72 hr
35oC
Why is CHOC plate added to isolate GC?
To cover for vancomycin susceptible strains
Cultural and non-cultural methods of detection of genital candidiasis.
BAP: growth at 24 hours; small white opaque colonies; feet at 48 hours

Germ Tube: Inoculate small volume plasma, 35oC for 3 hours; examine at 2-3 hours max; look for long tubular arm extending from cell
What does Group B Strep cause in newborns?
Pneumonia
Septicemia
and/or meningitis
Meningitis in newborn is caused by?
Group B Strep
Listeria
E. Coli
Best time, site and method of screening pregnant women for Group B Strep
Vag-Rectal Swab

35-37th week gestation
Development cycle of Chlamydia
EB (inert) phagocytozed by columnar cell
Organize into RB (replicative)
Multiply binary fission
Reorganize into EB
Cells dies, EB released
Why does Chlamydia need to live in human host?
Unable to make high-energy compounds such as ATP
What detection method is used for detecting LPS of EB?
DFA
What is a GC serological confirmation test? and how does it work?
Phadebact monoclonal GC Test

Uses monoclonal mouse abs that binds to the outer membrane of GC -> co-agglutination
What is in BIGGY?
Bismuth sulfite
Glucose
Glycine
Yeast