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7 Cards in this Set
- Front
- Back
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Shape of mitochondrial DNA
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circular
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Which respiratory chain complex does not contain an mtDNA encoded subunit
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Complex II
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What direction is mitochondrial DNA replicate
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Outer heavy chain replicates clockwise starting at 12 oclock. Inner light chain replicates counterclockwise at origin 8' oclock.
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Heteroplasmic cells
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Cells with mixture of mutant and normal mitochondrial DNA.
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Replicative segregation
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When the mitochondrial genotype of a heteroplasmic cell shifts during replication. Caused by random partitioning of normal and mutant mtDNAs into daughter cells during replication.
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5 Organs with highest mitochondrial need
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In order from most:
1) CNS 2) Skel Muscle 3) Heart 4) Kidney 5) Liver |
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Why cant u make DNA or RNA without mitochondria?
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Mitochondria contain rate limiting step in pyrimidine synthesis.
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