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10 Cards in this Set
- Front
- Back
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These are changes that occur in DNA that is exposed to the environment |
Induced changes |
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These are change that occur in DNA without any explanation |
Spontaneous changes |
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What type of genetic change can happen by error rates: |
Spontaneous |
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What are the 3 parts of an Error Rate? |
1. DNA polymerase 10^-6 error rate 3. Proofreading (exonuclease) 4. Post replication errors |
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Who began the field of DNA repair in 1949? |
Dr. Kelner |
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What are the 4 kinds of DNA repair? |
1. Direct 2. Basic Excision Repair 3. Nucleotide Excision Repair 4. Mismatch |
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In Direct DNA repair, what is the alkyl transfer? What's another name for direct repair? |
MGMT (methylguaninetransferase) Photoreactivation |
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What are the 4 steps to BER (Basic Exicision repair)? |
1. Glycosylase 2. Endonuclease 3. Polymerase 4. Ligase |
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What are the 3 Steps to NER (Nucleotide Excision Repair)? |
1. Excinuclease recognizes 2. DNA polymerase 3. DNA ligase |
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Are NER and BER interchangeable if need be? |
Yes |
