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7 Cards in this Set

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define
malformation
Deformation
Dysplasia
MAL:
structural defect from a local error in morphogenesis
DE:
a mechanical force causes an
abnormal shape
Dysplasia:
abnormal organization/function of a specific tissue type thruout the body
roughly how many (%) liveborns have major defects
3-4%, with 5-6% in the first yr of life
Genetics causes of malformations account for what percent? multifactorial? unknown? teratogenics?
:Genetics: 25.3
Multi: 23
Unknown - 43.2
Tera: 5
define
Pattern
Sequence
Oligohydramnios
PAttern - a characteristic set of traits generally seen together

SEquence - a pattern of anomalies derived from a single known defect or mechanical factor, symptoms that dont really classify as a syndrome, less specific, dont' always have similar presentation in a sequence

Oligo - too little amniotic fluid
Developmental field defect
pattern of anomalies caused by disturbed development of a related group of cells in the embryo
Syndrome
a pattern of anomalies consistently pathogenetically related to a single etiology
SPECIFIC
association
a group of anomalies occuring together more often then you would expect but not recognized with any syndrome
not necessarily like a sequence or syndrome which has a specific etiology