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101 Cards in this Set
- Front
- Back
chromos mutat
2 gr? |
ch in chrom numb
ch in chrom struct |
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2 types of ch in chrom numb
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1. aberrant euploidy
2. aneuploidy |
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aberrant euploidy is ?
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ch in whole chrom sets
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aneuploidy is?
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ch in parts of chromosome sets
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org that have more or fewer than the normal number of sets are?
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aberrant euploids
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polyploids are ?
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org with more than 2 chromosome sets
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3n is?
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triploid
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5n is?
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pentaploid
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ploidy level?
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is the number of sets of chrom
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monoploid is?
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an org that has only one chrom set
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male bees, wasps are ?
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monoploid
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male bees, wasps develop by?
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parthenogenesis
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genetic load?
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is the large number of deleterious recessive mutations
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why dont most monoploid in most species develop?
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bec of genetic load
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polyploidy is common in _______ but not in _________
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plants
not in animals |
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in aberrant euploids there is a correlat betw ___________ and size of the organ
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number of copies of the chromosome set
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a tetraploid org will look like its diploid counterpart but?
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will be bigger
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higer the ploidy level, the?
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larger the organ
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polyploids you can have
autopolyploids and ? |
allopolyploids
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allopolyploids are?
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have sets of chrom from 2 diff but closely related spec
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autopolyploids have multiple chromosome sets coming from?
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one species
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allopolyploids
the diff chrom sets are ____________, not homologous |
homeologous
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homeologous is?
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partially homologous
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triploids are usually?
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autopolyploids
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how can a geneticist make a triploid?
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cross a 2N with a 4n.
the 1n gamete will unite will the 2N gamete |
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triploids are usually sterile because?
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a gamete could receive either 2 or 1 chromosomes for each chromosome type
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triploids are aneuploid bec?
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they dont have 3 copies of every chromosome.
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polyploids with odd numbers of chrom numbers, like triploids, are?
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sterile or highly infertile
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autotetraploids come from the?
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doubling of 2N to 4N
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autotetraploids can be made artificially by?
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using chem that disrupt microtubule polymerization
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colchicine is a?
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common antitubulin agent
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a cell treated with colchicine will?
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have the s phase but chromosome segreg or cell division wont
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treating a 2n cell with colchicine will yield?
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a 4N cell
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what are the 3 diff meiotic possib in tetraploids?
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1. 2 bivalents
2. one quadrivalent 3. one univalent and a trivalent |
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autotetraploids
if chrom pair as bival or quadrivalents then you can have? |
chomosomes that segregate normally.
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autotetraploids
if trivalents form what will happen? |
segreg will lead to nonfunct aneuploid gametes
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tetraploid
A/A/a/a X A/A/a/a what will be odds of an a/a gamete? |
2/3 X 1/4= or 1/6
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tetraploid
A/A/a/a X A/A/a/a probab of a/a/a/a zygote is? |
1/6 X 1/6= 1/36
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tetraploid
A/A/a/a X A/A/a/a probab of A/-/-/- is ? |
1-1/36
or 35/36 |
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many species that act like normal diploids or haploids are descendants of?
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autopolypolids that occured in the past
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allopolyploids are?
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plant that is a hybrid of 2 or more species
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karpechenko made an allopolyploidy by?
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crossing cabbage with the radish.
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amphidiploid are ?
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doubled diploid.
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karpechenko
his sterile hybrid plant spontaneously? |
doubled
it became a amphidiploid. thus each chromosome had a pairing partner for meiosis |
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karpechenko
his radish and cabbage F1 hybrid had n + n =? |
9 + 9
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karpechenko
his radish and cabbage F1 hybrid spontaneously became? |
a fertile amphidiploid
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______________ has been a maj force in evol of new plant species
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allopolyploidy
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give an example of allopolyploidy giving rise to new species?
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3 species of Brassica combining with each other to form new species of plants
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you can make artificial allopolyploid plants by?
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fusing diploid cells from diff spec
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agricult applicat
why are monoploids good to have? |
1bec recess mutations will be phenotypically expressed and not covered up by diploidy
2. good allele combinations wont be broken up by recombinat |
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agricult applicat
having monopliods can prev good allele combinat from being broken up by? |
recombination
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how do you artif get a monoploid?
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a pollen grain cell can be cold treated. it will bec a embyroid
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embryoid is made by?
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cold treating a pollen cell
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monoploid cells can be exposed to mutagen and then selected for resistance to things like?
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plant parasites or herbicides
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autotriploids
give an ex of them? |
bananas
seedless watermelon |
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t or f
polyploidy in animals is rare |
t
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give 3 ex of polyploidy animals?
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worms, frogs, salemanders
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aneuploidy is?
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when a org differs by part of the chrom set
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trisomic means
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2n+1
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2n-1 is?
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monosomic
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2n-2 is?
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nullisomic
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in haploids
n+1 is? |
disomic
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disomic in ________ is n+1
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haploids
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what is the maj cause of most aneuploidy?
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nondisjunction
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mitotic nondisjunction during development results in?
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aneuploid sections of the body
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meiotic disj
can occur at ____________ meiotic division |
first or second
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n-1 gamete and a n gamete will make?
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a monosomic zygote
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n+1 gamete fertiliz by n gamete yields a?
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2n +1
trisomic |
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nondisj is more likely in meiosis ________?
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I
not II |
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why is nondisjunct more likely in Meiosis I?
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cause proph and met I require prop pairing of homolog chrom of the tetrad
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___________ are a necess component of the normal disjunct process
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crossovers
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format of a _______ helps hold the tetrad together
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chiasma
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in drosophil, most of the nondisjunct chrom are ?
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recombinant
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___________ are needed to maintain the intact tetrad until anaphase I
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crossovers
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monosomics are?
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2n-1
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Turner syndrome is?
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44 autosomes and
single X |
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Turner syndrome
what are its effects? |
sterile f
short |
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geneticists use viable plant monosomics to match recess mutant alles to ?
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a spec chromosome
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_________ have an extra copy of one chromosome
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trisomics
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2n +1 is?
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trisomic
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klinfelters syndrome is?
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XXY
lanky males, with mild retard |
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down syndrome is?
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trisomy of chrom 21
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who runs a higher risk of having children with Down syndrome?
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older mothers
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in females, eggs are arrested at?
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in late prophase I
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in females, eggs are arrested in late prophase I and ________ must stay assoc for a long time
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the chromosomal tetrad
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t or f
in female animals most nondisj happens at anaphase II |
false
anaphase I |
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patau syndrome is?
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trisomy 13
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trisomy 13 is?
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patau syndrome
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edwards syndrome is?
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trisomy 18
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Patua and edward sydrome?
what is their life expectancy? |
very short. less than a year
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plant aneuploidy
will look ? |
disproportionate in some way
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plant aneuploidy -disproport
plant polyploidy- ? |
proportionate but bigger
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in plant aneuploidy.
who is going to be more abnormal, the monosomic or the trisomic? |
the monosomic
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humans. who is more abnormal?
autosomal monosomics or trisomics? |
monosomics- they wont even survive
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ratio of A and B genes is 2A:3B.
this shows that the genes are? |
out of balance
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gene dosage effect is?
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that the more copies of a g you have the more g prod you have
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sometimes the imbal of aneuploidy result from?
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a few "major genes" on a chromosome
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the x chromosome has sex g and?
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housekeeping genes
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females XX
males XY but to correct for the double amount of g in the females you have? |
dosage compensation
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in mammals,
females one X is always? |
inactivated
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mammals
males the X chromosome is? |
hyperactive
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