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26 Cards in this Set

  • Front
  • Back
cell cycle
interphase, mitosis/meiosis
interphase
G0 (resting), G1 (cell growth), S (DNA replication), G2 (cell growth)
mitosis/meiosis
prophase, metaphase, anaphase, telophase
prophase
early- DNA condenses, late- nuclear envelope breaks up
metaphase
chromosomes line up (DNA tightly compact, can be visualized)
anaphase
microtubules contract, chromatids separate
telophase
nuclear membrane reforms
mitosis
cell division where chromosome number does not change
meiosis
sperm/ova formation, gametes contain 1 copy of each chromosome
chromosome
2 chromatids joined at centromere, have telomeres at ends, short + long arm
metacentric
centrosome at center
submetacentric
centrosome off center
acrocentric
centrosome at end
allosome
chromosomes that defines gender of organism (sex chromosomes)
autosome
not allosomes
sex determining systems
XXf/XYm (mammals), XXf/X0m (insects), ZWf/ZZm (birds), temp dependent (reptiles)
SRY gene
on y chromosome, determines sex in mammals, sry TF turns on SRY gene, turns on SOX9 gene, controls male development
aneuploidy
abnormal chromosome number (due to non-disjunction in anaphase)
euploidy
correct number of chromosomes
monosomy
lacking 1 chromosome of a pair
disomy
2 copies of a chromosome (NOT euploidy)
trisomy
3 copies of a chromosome
tetrasomy
4 copies of a chromosome
nondisjunction in allosomes
turner syndrome (X0), Klinefelter syndrome (XXY)
abnormal chromosome structure
translocation, deletions, inversions
chiasma
breaking of chromosomes during synapse, can cause rearrangement of regions of non-homologous chromosomes