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220 Cards in this Set

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~~Role of Protein~~
~~Role of Protein~~
What is the role of a protein?
To supply the body amino acids from which the body can make proteins.
What do proteins provide?
Energy.
How many kilocalories per gram does proteins contain?
4 kcal/gram
~~Chemical Structure of Protein~~
~~Chemical Structure of Protein~~
What chemical element does protein contain that carbohydrates & fats do not?
Nitrogen.
What is the building blocks of protein called? What connects the building blocks together?
Amino acids. Peptide bonds connect one amino acid to another.
Are proteins more complex or less complex than carbohydrates? Lipids?
More complex. Side groups vary-making proteins complex.
~~Nonessential Amino Acids~~
~~Nonessential Amino Acids~~
What is meant by “non-essential”?
Can be synthesized by the body.
~~Essential Amino Acids
~~Essential Amino Acids
What is meant by “essential”?
Cannot be synthesized at all or in sufficient amounts to meet physiological needs.
How many essential amino acids are there?
Nine.
Essential Amino Acids must be what?
Supplied by the diet.
~~Conditionally Essential~~
~~Conditionally Essential~~
Under special conditions, what does a nonessential amino acid become?
An essential amino acid.
What is Glutamine?
Preferred fuel of colonocyte during times of acute illness (immune enhancing).
What is Arginine?
Involved in cellular replication; wound healing, acute illness (immune enhancing).
~~Molecular Bonds~~
~~Molecular Bonds~~
Bonds that connect one amino acid to another amino acid are called by what name?
Peptide bonds.
~~Body Uses of Proteins~~
~~Body Uses of Proteins~~
What do proteins do in the body?
Build new cells, maintain tissues, and synthesize new proteins.
What are the functions of proteins?
Enzymes (all) - 50% of dietary protein, hormones, fluid and acid/base balance, and transporters (lipoproteins).
~~Digestion and Absorption~~
~~Digestion and Absorption~~
Where does protein digestion begin?
In the stomach with partial breakdown of proteins.
HCL does what in the digestion of proteins?
Uncoil each protein's strands so that digestive enzymes can attach the peptide bonds. Activates the enzyme Pepsinogen to activate form pepsin.
What does pepsin do?
Cleaves protein into smaller polypeptides and some amino acids.
What happens in the small intstine?
Pancreatic and intestinal proteases hydrolyze them further into short peptide chains (oligopeptides), tripeptides, dipeptides and amino acids.
~~Deamination of amino acids~~
~~Deamination of amino acids~~
What happens to amino acids during deamination?
Amino acids are stripped of their nitrogen containing groups so that they can be used for energy.
Deamination produces what?
Deamination produces ammonia.
What does the liver do during deamination of proteins?
Liver picks up the ammonia and converts it into urea -> back to blood
What do the kidneys do during deamination of proteins?
Kidneys filter urea out of the blood; nitrogen ends up in the urine.
~~Protein Metabolism: Nitrogen Balance~~
~~Protein Metabolism: Nitrogen Balance~~
What is Nitrogen Balance?
The balance between protein synthesis and protein degradation.
Where are the losses?
Losses in urine, drains, wounds.
Energy deficit or inadequate protein intake may force the body to do what?
To use amino acids as fuel, creating a negative nitrogen balance.
~~Proteins in Foods~~
~~Proteins in Foods~~
What are the three important characteristics of dietary proteins?
To supply all 9 essential amino acids, to supply enough total amino acids, and to be accompanied by adequate calories to prevent sacrifice of the body's protein.
~~Complete Proteins~~
~~Complete Proteins~~
What is a complete protein?
Contains all 9 essential amino acids and has the right proportion of each.
What are the sources of complete proteins?
Animal (eggs, meat, milk), etc. and soy.
~~Incomplete Proteins~~
~~Incomplete Proteins~~
What are incomplete proteins?
Missing (or low supply) of one essential amino acid.
What are sources of incomplete proteins?
Plants: grains, fruits, vegetables, legumes, nuts, and seeds have at least one limiting amino acid.
What is a limiting amino acid?
The "missing" essential amino acid.
~~Complimentary Proteins~~
~~Complimentary Proteins~~
What is it meant by complimentary proteins?
Combining various foods which contain different amino acids to make a complete protein.
Complementary proteins deal with what?
Food combining.
Complementary proteins do not need to what?
Be eaten at the same meal, just as long as it's in a 24 hour period.
Complementary proteins have been what?
Long standing traditions, such as peanut butter on bread.
~~Biological Value~~
~~Biological Value~~
What is it meant by Biological Value?
The greater the amount of nitrogen the body retains, the higher the Biological Value.
What food has a 100% of Biological Value, and thus is the standard by which all other proteins are measured?
Egg.
What is the Biological Value of Milk, Beef, and Corn?
93, 75, and 72.
~~Recommended Protein Intakes: How much does the body need?~~
~~Recommended Protein Intakes: How much does the body need?~~
What is the Recommended Protein Intake?
0.8 grams of protein per kg of body weight.
What is the calculation for Recommended Protein Intake when a person weighs 110 pounds?
Weight/2.2 = kg
Kg X 0.8 = daily recommended intake

So, 110/2.2. = 50kg.
50 kg x 0.8 = 40 grams of protein per day.
How much protein do Americans get every day?
More than enough.
What type of people need more protein?
Infants, children, adolescents, pregnant women, metabolically stressed patients (1.2-1.5 grams per kg), burn victims.
~~Too Much Protein~~
~~Too Much Protein~~
Which two organs stress if the body has too much proteins?
Stresses the liver and kidneys.
What mineral might be excreted in excess?
Calcium, which can increase risk for osteoporosis.
What vitamin is needed in extra amounts?
Vitamin B6.
Can you build more lean body mass simply by eating more protein?
No. Dietary protein does not automatically become lean body mass. Have to exercise for it.
~~Protein Energy Malnutrition~~
~~Protein Energy Malnutrition~~
Protein energy malnutrition is unusual in what?
Healthy people (USA).
Adult protein energy malnutrition comes from what?
AIDS, TB, Malabsorption syndromes, cancers, and eating disorders.
Worldwide, protein energy malnutrition is what?
Problematic.
What is Kwashiorkor?
Sudden/recent deprivation of food.
What does Kwashiorkor mean?
"The evil spirit that infects the first child when the second child is born".
What does Kwashiorkor look like?
"Swollen belly".
What are characteristics of the swollen belly?
Edema, enlarged liver, and often parasites.
What is Marasmus?
Disease of starvation caused by inadequate energy and protein intake over a long time period.
Who is at risk for Marasmus?
Often children 6-18 months old.
What does Marasmus look like?
Severe muscle wasting.
~~Vegetarianism~~
~~Vegetarianism~~
What are the positive aspects (health benefits) of vegetarianism?
Lowers body weight, lower blood pressure, less CAD, less GI disorders, lower cancer rates.
What are some negative aspects of vegetarianism?
Doesn't mean it's healthy and poor menu planning by many.
~~Terminology~~
~~Terminology~~
What is a Vegetarian?
Not really specific.
What is a Vegan?
No dairy, no eggs, no cheese.
What is Lacto-ovo?
Includes dairy and eggs.
~~Reasons for Vegetarianism~~
~~Reasons for Vegetarianism~~
What are the reasons for vegetarianism?
Health considerations, religious beliefs, food aversions and individual taste preferences, and animal rights.
~~Nutrition Concerns for Vegetarians~~
~~Nutrition Concerns for Vegetarians~~
What are some nutrients of concerns for vegetarians?
Iron (also found in leafy vegetables), zinc (also found in grains and nuts), calcium (also found in green leafy vegetables, broccoli, etc.), vitamin B12 (will need supplement), and Vitamin D (sunshine vitamin).
~~Vitamins - Chapter 6~~
~~Vitamins - Chapter 6~~
~~Discovery of Vitamins~~
~~Discovery of Vitamins~~
When were vitamins discovered? Symptoms have been reported when?
Recently. (1900's)
More than 2000 years ago.
What lead to the discovery of vitamins?
Symptoms of deficiency.
The symptoms of deficiency were thought to be what?
Protein deficiency. "Vital Amines".
~~Chemical Classifications~~
~~Chemical Classifications~~
Vitamins contain what?
A carbon.
The carbon in vitamins can be destroyed by what?
Heat, pH, and light.
What are the two categories of vitamins?
Fat and water soluble.
Vitamins are "non caloric". What does that mean?
They do not contain calories and do not supply energy.
~~Role in the Body: Vitamins~~
~~Role in the Body: Vitamins~~
Vitamins produce and release what?
Energy (ATP).
Vitamins play a part in cellular replication which does what?
Makes new tissues, deals with growth and development, plays a role in wound healing, and normal replication prevents cancer.
Vitamins are one type of what?
Antioxidant.
~~Water Soluble Vitamins~~
~~Water Soluble Vitamins~~
How many water soluble vitamins are there?
Nine. 8 B and 1 C.
When there is high blood levels of water soluble vitamins, the body does what?
Excretes, which is rarely toxic, but can have side effects.
How often do you need to consume water soluble vitamins?
Daily.
Where is water soluble vitamins found?
In the watery parts of the fruit or vegetable.
~~Fat Soluble Vitamins~~
~~Fat Soluble Vitamins~~
What are the fat soluble vitamins?
A, D, E, and K.
What parts of the body store surplus fat soluble vitamins?
The liver and body fat.
How often should you consume fat soluble vitamins?
Do not need to consume daily.
Megadoses of fat soluble vitamins can be what?
Toxic, including liver damage.
Where are fat soluble vitamins generally found?
In fats of foods.
What destroys fat soluble vitamins?
Deep fat frying (high heat).
What assists absorption of fat soluble vitamins?
Dietary fats and bile.
Fat absorption disorders can cause what?
Deficiency.
~~The B Vitamins - Thiamin~~
~~The B Vitamins - Thiamin~~
Thiamin releases energy from what?
Carbohydrates.
Thiamin is a crucial role in what?
Nerve processes.
What are the food sources of Thiamin?
Meats, legumes, fruits vegetables, and grains.
~~Thiamin Deficiency~~
~~Thiamin Deficiency~~
What does Thiamin deficiency affect?
Nerves, muscles, heart, and other organs.
What is Thiamin deficiency generally called?
Beri Beri.
What happens with Beri Beri?
Wasting of muscle tissue, swelling, paralysis, and heart enlarges with a irregular beat.
What does Beri Beri mean?
"I can't. I can't". Paralysis.
~~Thiamin Info for Nurses~~
~~Thiamin Info for Nurses~~
Who is mostly at a risk for thiamin deficiency?
Alcoholics.
When alcoholics come into the hospital, they are given what?
IV or IM thiamin for three days.
Thiamin can be added to what?
IV's because it's inexpensive. Less than $1.30 per day.
Thiamin can be infused through what?
Peripheral Access.
Thiamin deficiency can lead to what?
Wernicke's Encephalopathy.
~~The B Vitamins - Riboflavin~~
~~The B Vitamins - Riboflavin~~
What color is riboflavin?
Blue/purple.
What does Riboflavin release?
Energy, like all vitamins.
Are deficiencies rare or common?
Rare.
What are some signs of a deficiency?
Skin problems, cracks at corner of mouth, red swollen tongue, and teary, bloodshot eyes.
~~Riboflavin Sources~~
~~Riboflavin Sources~~
What are some sources of Riboflavin?
Milk, dairy products, meat, dark green veggies, and grains.
What destroys Riboflavin sources.
UV Rays.
~~The B Vitamins - Niacin~~
~~The B Vitamins - Niacin~~
Niacin obtains energy from what?
Foods.
The deficiency of Niacin is called what?
Pellagra.
Pellagra's symptoms contain what?
(3-4 D's) Diarrhea, dermatitis, dementia, and death.
~~Niacin Sources~~
~~Niacin Sources~~
Where is Niacin found?
Milk, eggs, meat, poultry, and fish.
What is Niacin used as?
Drug-like supplement to lower LDL cholesterol, and raise HDL.
Niacin has what type of side effects for being used as a drug-like supplement?
Flushing, and hot.
Niacin supplement must be what and what is the dosage?
Prescribed by a doctor. 10-15 X RDA.
~~The B Vitamins - Folate/ Folic Acid~~
~~The B Vitamins - Folate/ Folic Acid~~
Folic acid plays a role in what?
Red Blood Cells and DNA Synthesis.
The deficiency of Folic Acid can lead to what?
Anemia, birth defects (neural tube: spina bifida), and high homocysteine levels.
What are the sources of Folate?
Vegetables, Legumes, and Seeds.
How much Folate is needed and by who?
400 mg daily. Women of childbearing age.
When is folate needed most?
Before pregnancy and during the first few weeks.
~~The B Vitamins - B6~~
~~The B Vitamins - B6~~
What is B6 needed for?
Protein metabolism.
Where do we get B6 from?
Proteins, veggies, and grains.
The deficiency of B6 leads to what?
Weakness, irritability, insomnia, immune suppression, and CVD.
~~ The B Vitamins - B12~~
~~The B Vitamins - B12~~
What does B12 protect?
Nerve fibers.
B12 works with what?
Folate to produce red blood cells.
The deficiency of B12 leads to what?
Anemia. Creeping paralysis of nerves and muscles (can be permanent if left untreated).
Extra folate can do what to anemia?
Treat it, but cannot mask other symptoms.
B12 deficiency is unlikely in people who eat meat but may what?
Occur with strict vegans.
Where are vegan sources of B12?
Fortified soy beverages, fortified cereals, supplements.
What requires B12 injections?
People with genetic defect that hampers body’s ability to product intrinsic factor – compound that enables absorption.
~~The B Vitamins – Pantothenic Acid and Biotin~~
~~The B Vitamins – Pantothenic Acid and Biotin~~
Pantothenic Acid and Biotin are needed for what?
Coenzyme synthesis in multitude for body’s system.
Biotin is required in what?
Cell growth, DNA synthesis, and maintenance of blood glucose levels.
Pantothenic Acid and Biotin are found there?
In a wide variety of foods.
~~Vitamin C~~
~~Vitamin C~~
What is Vitamin C required for?
The production and maintenance of collagen.
What is Vitamin C touted as?
A stress fighting nutrient.
What does Vitamin C boost?
The body's ability to fight infections.
Vitamin C is a type of what?
Antioxidant.
Vitamin C could be...?
A cure for the common cold.
Growing evidence of Vitamin C suggests what?
That it protects against CVD and certain types of cancers.
What are sources of Vitamin C?
Citrus fruits (oranges, lemons, limes), broccoli, brussel sprouts, potatoes, cantaloupe, and strawberries.
What is the deficiency of Vitamin C called?
Scurvy.
Who is at a risk for Scurvy?
Infants, children (limited diet), elderly.
~~Fat Soluble Vitamins~~
~~Fat Soluble Vitamins~~
~~Vitamin A~~
~~Vitamin A~~
Vitamin A is what compared to other Vitamins?
Most versatile.
What is Vitamin A important for?
Many body processes, such as vision.
With Vitamin A, the body can make what?
Retinal.
What is the deficiency of Vitamin A?
Vision problems and night vision.
What are other roles of Vitamin A?
Healthy skin, sperm production, fetal development, immune system, hearing, taste, growth.
~~Vitamin A Storage~~
~~Vitamin A Storage~~
How much Vitamin A can be stored?
A years supply.
How much of that Vitamin A is stored in the liver?
90%
What is bad about Vitamin A?
Can be very toxic if overdose.
What are signs of deficiency?
Joint pain, hair loss, irritability, fatigue, headaches, weakness, nausea, and liver damage.
Deficiency is what?
Widespread.
Vitamin A can lead to what?
Keratomalacia.
What is Keratomalacia?
Blindness.
~~Beta-Carotene~~
~~Beta-Carotene~~
Beta-Carotene is not what?
A fat soluble Vitamin.
What is Beta-Carotene?
A Vitamin A precursor.
What are the sources of Beta-Carotene?
Fruits and vegetables. Yellow, orange, red, and green fruits and vegetables.
What contains Vitamin A?
Milk and dairy.
~~Vitamin D~~
~~Vitamin D~~
What "team" is Vitamin D on?
Bone-making/maintenance team.
What does Vitamin D assist with?
Calcium absorption and calcium and phosphorous in blood.
What is Vitamin D nicknamed?
Sunshine vitamin.
~~Vitamin D Intake~~
~~Vitamin D Intake~~
What are food sources of Vitamin D?
Eggs, liver, some fish.
What is Vitamin D deficiency in children?
Rickets.
What is Vitamin D deficiency in adults?
Osteomalacia.
Excess intake of Vitamin D may what? Also, what is an example?
Cause calcium to be deposited in soft tissue. Kidney stones.
~~Vitamin E~~
~~Vitamin E~~
Vitamin E is what?
Found widespread in foods.
Where is Vitamin E found?
Oils, margarine, salad dressings, shortenings, nuts and seeds, some in fruits, vegetables, and grains.
Intake of Vitamin E protects what?
The heart, lungs, brain, and other organs.
Vitamin E antioxidant is what?
Scavenger of free radicals.
Toxicity of Vitamin E can what?
Impair blood clotting.
~~Vitamin K~~
~~Vitamin K~~
Where you here Vitamin K, think of what?
Koagulation, which is blood clotting.
What is Vitamin K made by?
Intestinal flora.
Vitamin K is given to whom?
Newborns, as an injection.
What are sources of Vitamin K?
Green leafy vegetables, cabbage family.
What is a food-drug interaction with Vitamin L
Warfarin or Counadin.