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67 Cards in this Set

  • Front
  • Back

Conducting Airways

  • )Upper Airway- leads inspired air down
  • Lower Airway-leads inspired air into lungs

Anatomic Dead Space

  • AMOUNT of air in conducting airways
  • does NOT reach alveoli
  • avg 1ml dead space per 1lb of body weight

ex: 150lb x 1ml = 150ml dead space

Airway Resistance

  • (Raw)
  • the blocked airflow through conducting airway
  • Pressure/Flow = Raw
  • Normal Raw = .5 - 1.5 cmH2O/L/sec

Cause of Raw

Bronchoconstriction - due to inflammation, smooth muscle constriction, secretions, or tumors



Endotracheal Tube (ET) being too small or kinked

Upper Airway Consists of:

  1. Oral Cavity
  2. Nasal Cavity
  3. Pharynx
  4. Larynx

Oral Cavity (Mouth)

  1. Assists in digestion
  2. Assists in speech
  3. Accessory passage for ventilation

Uvula

- Soft fleshy structure hanging from soft palate


- Prevents food from going into Nasal cavity


- Can cause OSA (obstructive sleep apnea) if too large


Tongue

- Skeletal muscle tissue located on floor of oral cavity


*most common cause of airway obstruction in unconscious patient

Tonsils

  1. Pharyngeal
  2. Palatine (lymph tissue, immune defense functions


- located on each side of oral cavity

Hard and Soft Palate

  • Hard Palate formed by palatine bones
  • Soft Palate formed by flexible collagen fibers

Nasal Cavity

  1. Heat (inspired air)
  2. Filter (inspired air)
  3. Humidify (inspired air)

Roof of Nasal Cavity

Formed by:


- nasal bones


- frontal process of maxilla


- cribform plate of ethmoid bone

Floor of Nasal Cavity

Formed by:


-Palatine process of maxilla


-Palatine bones (same as roof of mouth)

Alar Cartilage

Lower portion of nose


Vestibule

Space inside the alae (in alar cartilage) containing the vibrissae


- vibrissae are hair follicles that filter the inspired air

Nares

-Openings through which air enters the nasal cavity


- Formed by the nasal septum

Septum

- Internal cartilage of the nose


-separates nasal cavity into 2 chambers

Conchae/Turbinates

-3 bony shelves (turbinates) projecting into the nose


- where inspired air contacts with warm, moist, nasal passages


*important in humidifying and warming gases


-very vascular


- Divides nasal cavity into Superior, Middle, and Inferior passages


Pharynx

Passageway for inspired air between nasal cavity and larynx


-Oropharynx


-Nasopharynx


-Laryngopharynx

Oropharynx

Palatine tonsils "the tonsils" are located here

Nasopharynx

Pharyngeal tonsils (adenoid tonsils) & Auditory tubes are located here



-Auditory tubes purpose is to equalize pressure in middle ear.


-Middle ear mucosa is continuous with pharynx mucosa


Laryngopharynx

-Air passageway between base of tongue and esophagus


-Gag reflex located here


-Gag prevents aspiration of food and liquid


Larynx

Air passageway between pharynx and trachea


-Cartilage


-Epiglottis


-Vocal cords

Thyroid Cartilage

"Adams Apple"


-largest cartilage (in that area)

Cricoid Cartilage

*only rigid structure that completely encircles the airway



Cricothyrotomy- Emergency opening of the airway performed on the ligament between the cricoid and thyroid cartilage


Epiglottis

Diverts the food away from the trachea and esophagus during swallowing

Vocal Cords

2 pairs of folds of muscle on the interior of the larynx


*False vocal cords- upper pair of folds


*True vocal cords- Lower pair of folds

Glottis

-Space between the two pairs of vocal cords



-Opening into the lower airway (lower respiratory tract) (trachea)


Upper Airway Protective Mechanisms

  1. Nose filters out particles (vibrissae)
  2. Gag reflex- nerve endings on tongue
  3. Epiglottis diverts food away from trachea

The Lower Airways

Tracheobronchial tree

Trach tree refers to the lower airways leading to the lungs

Lower Airways Consist of:

  1. Trachea
  2. Carina
  3. Right Main Stem Bronchus
  4. Left Main Stem Bronchus
  5. Lobar Bronchi
  6. Segmental Bronchi
  7. Sub segmental Bronchi
  8. Bronchioles
  9. Terminal Bronchioles

Cartilaginous Airways

Airways with cartilage



trachea > main stem bronchi > lobar bronchi > segmental bronchi > sub segmental bronchi



*cartilage is important to give structure and support to keep airway open

Trachea

-supported by cartilage


- 10-12cm long


- 1.5 - 2.5cm diameter


- located midline in neck

Carina

Area just before trachea divides into L & R main stem bronchus

Right Main Stem Bronchus

-Bronchi are LARGE air passages


-Branches off from trachea @ a 25 degree angle


-supported by cartilage


(Endotrach tube- if pushed too far, will only go into and feed R MSBronchus)

Left Main Stem Bronchus

-Bronchi are Large air passages


- Branches off from trachea @ a 40-60 degree angle


-Supported by cartilage

Lobar Bronchi

-Large airways direct gases to the upper lobes, middle lobes, and lower lobes of the lungs


-Supported by cartilage

Segmental Bronchi

-Large airways always directs gases to specific segments in each lobe of the lung


-10 segments in R lung


-8 segments in L lung


-supported by cartilage

Sub segmental Bronchi

-progressively smaller airways


-1-4 mm


-supported by cartilage

Bronchioles

*Small airways less than 1mm in diameter


- NOT supported by cartilage


Terminal Bronchioles

-end of conducting airways


-0.5 mm diameter


-NOT supported by cartilage

Histology of Tracheobronchial Tree

  1. Epithelial lining (interior)
  2. Lamina propia (middle)
  3. Cartilaginous layer (around outside)

Epithelial Lining

-pseudo stratified ciliated columnar epithelium cells


-200 cilia per cell


*NO cilia past terminal bronchioles

Epithelial Lining cont.

Mucous Blanket & Mucociliary Escalator

Mucous Blanket- covers epithelial lining.


-goblet cells, submucosal glands, and bronchial glands produce mucous.


Mucociliary escalator- cilia moving in wavelike motion to move particles at a rate of 2cm/min

Epithelial Lining cont.

Gel/Sol Layer

Gel- particles are caught in viscous layer



Sol- cilia movement, propels particles to larynx

Lamina Propia

-sub mucosal layer


-consists of smooth muscle fiber


*(when they constrict, they squeeze the airway, and the patient wheezes)


*- Mast cells- release HISTAMINE and LEUKOTRINES

Cartilaginous Layer

-outer layer of tracheobronchial tree


-protects and supports the airway


-keeps airway open

Respiratory Zone

Acinus, parenchyma, and functional units



*Anatomical structures where gas exchange occurs*


Consists of:


  1. Respiratory bronchioles
  2. Alveolar ducts
  3. Alveolar sacs
  4. Alveoli

Respiratory Bronchioles

-smaller airways leading gases to the functional units


Alveolar Ducts & Alveolar Sacs

Ducts- openings to sacs



Sacs- groups of pouches leading to alveoli


Alveoli

*Out pouching of walls through which gas exchange between alveolar air and capillary blood takes place

Primary Lobule

- respiratory bronchioles, ducts, sacs and alveoli collectively make this



*approx. 130,000 primary lobules in the lungs

Alveolar Epithelium

Type I cells: thin cells, site of internal gas exchange



Type II cells: produce surfactant, which decreases surface tension on alveoli

Pores of Kohn

- Holes in walls of alveolar septum



-permits gas to move between adjacent alveoli

Alveolar Macrophage

-located in lining of alveolar surface




-purpose: to remove bacteria and foreign particles

The Lung

-Highly elastic tissue and collagen fibers called lobes



Fissures- dark lines that divide lobes

Right Lung vs Left Lung

  1. Upper lobe
  2. Middle lobe
  3. Lower lobe


  1. Upper lobe
  2. Lingula
  3. Lower lobe

Interstitum

  1. Area between alveolar epithelium and pulmonary capillary
  2. Area around bronchioles, resp bronchioles, alv ducts and alv sacs

**Interstitum collagen LIMITS distensibility

Pulmonary Vascular System

- vessels that bring the blood flow to & from the alveoli

Pulmonary Arteries

*Delivers DEOXYGENATED blood to arterioles

Pulmonary Arterioles

*Delivers DEOXYGENATED blood to pulmonary capillaries

Pulmonary Capillaries

-surround alveoli


*GAS EXCHANGE occurs here

Pulmonary Venules

*Delivers OXYGENATED blood to pulmonary veins

Pulmonary Veins

*Delivers OXYGENATED blood back to the heart

Alveolar - Capillary Membrane

(AC Membrane)

*Point of gas exchange where pulmonary capillaries surround alveoli


-Diffusion moves O2 from alveoli into capillary blood


-Diffusion moves CO2 from the venous blood into the alveoli


***Internal Gas Exchange can being ONCE INSPIRED GAS REACHES ALVEOLI

Diffusion

-Movement of MOLECULES from are of high concentration to an area of lower concentration



*Diffusion of O2 &CO2 across AC membrane is a result of high concentration and resulting diffusion gradients

P A O2 = PAO2

V

Partial pressure of oxygen in the Alveoli


V= venous