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87 Cards in this Set

  • Front
  • Back
What does water mean to the human body?
Water is the most important nutrient for life
Water is the primary body fluid
Adult weight is 55-60% water
Loss of 10% body fluid= 8% weight loss SERIOUS
Loss of 20% body fluid= 15% weight loss FETAL
Fluid gained each day should = fluid lost each day (2-3 L/day average)
What is the minimum output per hour necessary to maintain renal function?
30 mL

If minimum needs are not met, it results in renal failure

Watching someone's weight is crucial to maintaining fluid balance

Output isn't always exactly equal to input because there are other ways of releasing fluids, ie: diaphoresis
What are the functions of body fluid?
Medium for transport
Needed for cellular metabolism
Solvent for electrolytes and other constituents
Helps maintain body temperature
Helps digestion and elimination
Acts as a lubricant
What are the mechanisms of fluid gain and loss?
Gain
Fluid intake 1500 ml
Food intake 1000 ml
Oxidation of nutrients 300 ml
(10ml of H2O per 100 kcal)

Loss
"Sensible"
Can be seen
Urine 1500 ml
Sweat 100 ml

"Insensible"
Not visible
Skin (evaporation) 500 ml
Lungs 400 ml
Feces 200ml
What does the hypothalamus have to do with regulation of fluids?
Thirst receptors (osmoreceptors) continuously monitor serum osmolarity (concentration). If it rises, thirst mechanism is triggered.
Describe pituitary regulation of fluids.
Posterior pituitary releases ADH (antidiuretic hormone) in serum response to increasing osmolarity. Causes renal tubules to retain H2O
What does renal regulation have to do with renal regulation?
Nephron receptors sense decreased pressure (low osmolarity) and kidney secretes RENIN
What does angiotensin II do to regulate fluids?
Causes Na and H2O retention by kidneys
&
Stimulates adrenal cortex to secrete aldosterone which causes kidneys to excrete K and retain Na and H2O
also
ANP (atrial natriuretic peptide) hormone is secreted by atrial cells of heart in response to atrial stretching
What does angiotensin II cause?
vasoconstriction
What does an increase is ADH do to the urinary output?
decrease in urinary output
What holds a greater % of water, muscle tissue or aipose tissue (fat)?
Muscle tissue
What is intracellular fluid?
ICF
Fluid inside the cell
Most (2/3) of the body's H2O is in the ICF
What is extracellular fluid?
ECF
Fluid outside the cell
1/3 of the body's H2O
More prone to loss
What are the 3 types of extracellular fluid?
Interstitial
fluid around/between cells

Intravascular
(plasma) fluid in blood vessels

Transcellular
CSF, synovial fluid, etc
What is the relationship between age and total body water?
Total body water decreases from birth to adolescence
Describe fluid balance.
Dynamic process
Balance between body fluids and electrolytes
Attraction between ions (electrolytes) and water (fluids) causes fluids to move across membranes and leave their compartments
What is osmosis?
The main way fluids move

Water shifts from low solute/high water concentration
to
high solute/ low water concetration to reach homeostasis (balance)
What does semi permeable mean?
The cell membrane only allows certain particles through, one of which is water molecules
What is osmolarity?
The concentration of particles in a solution
What is osmotic pressure?
The greater the osmolality of a solution, the greater the pulling force
What is normal serum (blood) osmolality?
275-295 mOSM/kg
What is a hypertonic solution?
A solution that has a high osmolality and is one that is > serum osmolality
What is a hypotonic solution?
A solution that has low osmolality is one that is < serum osmolality
What is an isotonic solution?
A solution that has equal osmolality to serum
If a patient has a lot of edema, what kind of solution would you give?
hypertonic
If the serum is very concentrated, what kind of solution would you give?
hypotonic
What are crystalloids?
Solutions that have small particles in them
They work mainly by osmotic properties
These are our common IV solutions
What are colloids?
Solutions with large particles
They have a stronger pulling action
ex: blood and blood components
Describe hypertonic fluids.
Hypertonic fluids have a higher concentration of particles (high osmolarity) than ICF

The higher osmotic pressure shifts fluid from cells into the ICF

Therefore cells placed in a hypertonic solution will shrink

Used to expand vascular volume

Fosters normal BP and good urinary output
What are some types of IV solutions which are hypertonic?
D5% 0.45% NS (D5 1/2 NS)
D5% NS (D5 NS)
D5% LR (D5 LR)
Why are hypertonic solutions not commonly used with patients who have renal or cardiac disease?
Because aldosterone releases increases as a result of decreased blood pressure
Describe hypotonic fluids.
Hypotonic fluids have less concentration of particles (low osmolality) than ICF

This low osmotic pressure shifts from ECF into cells

Cells placed in a hypotonic solution will swell

Used to "dilute" plasma particularly in hypernatremia
What are some types of IV solutions that are hypotonic?
0.45% NS
0.33% NS
In what type of patient conditions would a hypotonic IV solution be contraindicated?
If someone had a lot of edema

Increased intracranial pressure
Describe isotonic solutions.
Isotonic fluids have the same concentration of particles (osmolality) as ICF (275-295 mOsm/L)

Osmotic pressure is the same inside and outside the cells

Cells neither shrink nor swell in an isotonic solution, they stay the same

Expands both intracellular and extracellular volume

Most commonly used
-treatment for excessive vomiting, diarrhea
What are some common isotonic IV solutions?
0.9% normal saline
D5W
Ringer's Lactate (also contains some Na, K, Ca, Cl
Are isotonic solutions always safe?
No

D5W needs to be used carefully because when glucose is metabolized, it releases more water

RL is known to stimulate inflammatory responses (neutrophils released) and can cause ARD (acute respiratory distress) in trauma patients
What should you know about albumin and osmosis?
Albumin in the serum has osmotic properties called colloid pressure

Albumin pulls H2O from the interstitial compartments into the intravascular compartments (serum). Helps to maintain BP.

Persons with low serum albumin levels tend to retain fluid in the interstitial layers
What causes the solute to move by diffusion?
Movement of solutes from high concentration to low concentration

It is a passive movement down the concentration gradient

Many body processes use diffusion
ex: O2, and CO2 exchange

Rate is affected by: concentration gradiant, permeability-surface area thickness of membranes, and size of particles (Fick's Law)
What abnormal assessments might you find in the client with low serum albumin levels?
3rd spacing

low blood pressure
What would be of benefit to give a patient with low albumin levels?
D5NS (hypertonic)
Describe active transport.
It requires energy (ATP) to move from low concentration to high concentration (uphill)

May be enhanced by carrier molecules with binding sites on cell membrane

ex: glucose
(insulin promotes the insertion of binding sites for glucose on cell membranes
What is filtration?
Solvent and solute movement
What is hydrostatic pressure?
Passage from an area of high pressure to an area of low pressure

ex: arterioles have higher pressure than ICF fluid, oxygen and nutrients move into cells
venules have lower pressure than ICF fluid, carbon dioxide and wastes move out of cells
What is fluid volume deficit?
Loss of both H2O and electrolytes from ECF

Causes include:
increased output, hemorrhage, vomiting, diarrhea, or burns
or
fluid shift out of vascular space into interstitial spaces ("third spacing")
What is hyperosmolar imbalance (hypertonic dehydration)?
H2O loss greater than electrolyte loss; excessive perspiration, diabetes insipidus (profuse urination)
How would you assess for fluid volume deficit?
Cardiovascular:
Diminished peripheral pulses; quality 1+ (thready)
Decreased BP and orthostatic hypotension
Increased HR
Flat neck and hand veins in dependent position
Elevated hematocrit (Hct)

Gastrointestinal:
Thirst
Decreased motility; diminished bowel sounds, possible constipation

Neuromuscular:
Decreased CNS activity (lethargy to coma)
Possible fever
Skeletal muscle weakness
Hyperactive DTR

Renal:
Decreased output
Increased specific gravity of urine
Weight loss
Hypernatremia
What is a nursing diagnosis for fluid volume deficit?
Deficient fluid volume r/t loss of GI fluids via vomiting AEB elevated Hct, dry mucous membranes, decreased output, thirst
What should the RN plan for FVD?
Patient will demonstrate fluid balance AEB moist mucous membranes, balanced I & O measurements, Hct WNL, by....... (insert time frame)
What would the RN implement in regards to FVD?
Prevent further fluid loss
Oral rehydration therapy
IV therapy
Medications; antiemetics; antidiarrheals
Monitor CV, Resp, Renal, GI status
Monitor electrolytes- possible supplement Rx
Monitor weight and I & O
Health promotion: heat and hydration safely
What is overhydration?
Fluid overload is an excess of body fluid
What is hypervolemia?
Excess fluid volume in the intravascular area
What is edema?
Excess fluid volume in interstitial spaces
What causes fluid volume excess?
Increased Na/H2O retention
Excessive intake of Na (PO or IV)
Excessive intake of H2O (PO or IV) (water toxication)
Syndrome of inappropriate antidiuretic hormone (SIADH)
Renal failure, congestive heart failure
What drug stimulates ADH?
Ectasy
How would you assess for fluid volume excess?
Cardiovascular:
Elevated pulse; 4+, bounding, elevated BP, distended neck and hand veins, ventricular gallop (S3), Hyponatremia

Respiratory:
Dyspnea, Moist crackles, Tachypnea

Integumentary:
Periorbital edema
Pitting or non-pitting edema

Gastrointestinal?
Increased motility
Stomach cramps
Nausea and vomiting

Renal:
Weight gain
Decreased specific gravity of uring

Neuromuscular:
Alreder LOC, headache, skeletal muscle twitching
What is a nursing diagnosis related to fluid volume excess?
Excess fluim volume r/t excessive H2O intake, AEB confusion, headache, muscle twitching,abdominal cramps. Elevated BP and HP. hyponatremia.
What should the RN plan for a patient with FVE?
Client will demonstrate fluid balance by balanced I & O measurements, serum Na WNL, etc by.....
What should the RN do to implement proper care for a patient with FVE?
Restore normal fluid balance
Prevent further overload
Drug therapy; diuretics
Diet therapy; decrease Na & fluids
Monitor weight and I & O
Monitor electrolytes
Monitor CV, respiratory, Renal systems
Health promotion: teach patients with cardiac disease to weigh daily and report a significant day to day gain
What is the purpose of electrolytes in our body?
They work with fluids to keep the body healthy and in balance
What are electrolytes?
They are solutes that are found in various concentrations and measured in terms of milliequivalent (mEq) units

They can be negatively charged (anions) or positively charged (cations)

For homeostasis, body needs:
total body anions = total body cations
Compare/contrast anions and cations
Cations
positively charged
Sodium Na+
Potassium K+
Calcium Ca++
Magnesium Mg++

Anions
Negatively charged
Chloride Cl-
Phosphate PO4-
Bicarbonate HCO3-
What are the functions of electrolytes?
Regulate water distribution
Muscle contraction
Nerve impulse transmission
Blood clotting
Regulate enzyme reactions (ATP)
Regulate acid-base balance
What should you know about sodium?
Na+
135-145 mEq/L
Major Cation
Chief electrolyte of the ECF
Regulates volume of body fluids
Needed for nerve impulse & muscle fiber transmission (Na/K pump)

Regulated by:
Kidneys
Hormones (Aldosterone, Renin, ADH)
What is Hyponatremia?
Serum Na+ < 135 mEq/L
Caused by:
increased water
loss of Na+
Water shifts from ECF into cells
S/S: H/A, confusion, muscle weakness, N/V, abd cramps (hyperactive bowel sounds, hypotension, tachycardia
Tx: Diet/IV therapy/Fluid restrictions
What is hypernatremia?
Serum Na+ > 145 mEq/L
Cause:
Na+ gained in excess of H2O
Water is lost in excess of Na+
Water shifts from cells to ECF
S/S: thirst, dry mucous membranes & lips, oliguria, increased temp & pulse, flushed skin, confusion, irritability, muscle twitching
What are some implementations for sodium imbalance?
Hypo
Increase oral Na intake
Fluid restriction
Hypertonic IV fluids
What should you know about potassium?
3.5-5.0 mEq/L
Chief electrolyte of ICF
Major mineral in all cellular fluids
Aids in muscle contraction, nerve & electrical impulse conduction, regulates enzyme activity, regulates IC H2O content, assists in acid-base balance
Regulated by kidneys & hormones
Inversely proportional to Na
What is Hypokalemia?
Serum level < 3.5 mEq/L
Results from decreased intake, loss via GI/Renal & potassium depleting diuretics
Life threatening-all body systems affected
S/S: muscle weakness & leg cramps, decreased GI motility (N/V Anorexia), cardiac arrhythmias d/t cardiac irritability: PACs, PVCs, possible VT, VF, death
What does too much potassium do to the heart?
slows it to the point of potentially stopping all together
What is hyperkalemia?
Serum level > 5 mEq/L
Results from excessive intake, trauma, crush injuries, burns, renal failure
S/S: muscle weakness, cardiac changes slowed cardiac conduction, decreased HR leading to cardiac arrest, N/V, increased GI motility & diarrhea, parathesias of face/fingers/tongue
What RN implementations would be taken to correct potassium imbalances?
Hypo
Dietary potassium or supplements
IV potassium added to IV fluids
IVs with K added should should always be on a pump and ideally into a central line

Hyper
IV diuretics
IV fluids to dilute
Kayexalate (draws potassium to it)
If severe:
IV calcium chloride & IV calcium gluconate (stimulate conduction of heart to prevent cardiac arrest)
IV sodium bicarb and IV insulin (shifts potassium out of the blood and back into cells
Dialysis
What should you know about calcium?
4.4-5.5 mEq/L
Most abundant in body but:
99% in teeth and bones
Needed for nerve transmission, vitamin B12 absorption, muscle contraction & blood clotting
Inverse relationship with phosphorous (regulated by parathyroid hormone PTH)
Vitamin D needed for Ca absorption
What is Hypocalcemia?
Serum Ca < 4.3 mEq/L
Results from low intake, loop diuretics, parathyroid disorders, renal failure, common after thyroid surgery
S/S: lethargy, EKG changes, decreased HR and BP, numbness/tingling in fingers, muscle cramps/tetany, seizures, Chovstek Sign & Trousseau Sign
Tx: diet/IV therapy
What is Hypercalcemia?
Serum Ca> 5.3 mEq/L
Results from hyperparathyroidism, some cancers, prolonged immobilization, high intake of supplements wit hCa and Vit D
S/S: muscle weakness, renal calculi, lethargy, fatigue, altered LOC, decreased GI motility, constipation, cardiac changes (decreased HR)
What implementations should the RN be making to correct calcium imbalance?
Hypo
To increase HR:
IV calcium gluconate
IV calcium chloride
PO Aluminum hydroxide gel (binds to phosphorous)
Vit D-aids absorption
Diamox (promotes phosphorous excretion)

Hyper
IV saline and /or diuretics (increases Ca excretion)
Steroids-decrease intestinal absorption of Ca
Phosphorous replacements
Calcitonin-promotes excretion
Dialysis
Calcium Chelators:
Mithramycin (anti-neoplastic) stimulates Ca uptake by bones therefore reducing Ca in serum
What is a chelator?
Aids the excretion of something out of the body because of an excess
What should you know about magnesium?
1.5-2.5 mEq/L
Most located within the ICF
Needed for activating enzymes, electrical activity, metabolism of carbs/proteins, DNA synthesis
Regulated by intestinal absorption and kidney
What is Hypomagnesemia?
Serum <1.5 mEq/L
Results from decreased intake, prolonged NPO status, chronic alcoholism & nasogastric suctioning
S/S: muscle weakness, cardiac changes (cardiac irritability) mental changes, hyperactive reflexes & other hypocalcemia s/s
Common in critically ill patients
Associated with high mortality rates
Increases cardiac irritability and ventricular dysrhythmias- especially in patients with recent MI
Maintenance of adequate serum MG has been shown to reduce mortality rates post MI
What is hypermagnesemia?
Serum >2.5 mEq/L
Results from renal failure, increased intake (laxatives with Mg)
S/S: flushing, lethargy, cardiac changes (decreased HR and BP), decreased respirations, loss of deep tendon reflexes
What implementations should the RN do in order to correct Magnesium imbalances?
Hypo
Oral Magnesium
Restore Ca levels
IV magnesium

Hyper
Diuretics to promote Mg loss
Calcium gluconate to promote cardiac function
Dialysis
What should you know about Chloride?
95-105 mEq/L
Most abundant anion in ECF
Combines with Na to form salts
Maintains water balance, acid-balance, aids in digestion (hydrochloric acid) & osmotic pressure (with Na and H2O)
regulated by kidneys
Follows sodium (Na)
What is Hypochloremia?
Serum level < 96 mEq/L
Results from prolonged vomiting and suctioning
S/S:metabolic alkalosis, nerve excitability, muscle cramps, twitching, hypoventilation, decreased BP if severe
Tx: diet/ IV therapy
What is hyperchloremia?
Serum level > 106 mEq/L
Results from excessive intake or retention by kidneys-metabolic acidosis
S/S: Arrhythmias, decreased cardiac output, muscle weakness, LOC changes, Kussmaul's respirations
Tx: restore fluid & electrolyte balance
What should you know about phosphate?
1.8-2.6 mg/dl
Needed for acid-base balance, neurological & muscle function, energy transfer ATP & affects metabolism of carbs/proteins/lipids, B vitamin synthesis
Found in the bones
Regulated by intake and the kidneys
Inversely proportional to calcium (therefore some regulation by PTH as well)
What is hypophosphatemia?
Serum level < 1.8 mEq/L
Results from decreased intestinal absorption and increased excretion
S/S: bone & muscle pain, mental changes, chest pain, resp failure
Tx: Diet/IV therapy
What is Hyperphosphatemia?
Serum level > 2.6 mEq/L
Results from renal failure, low intake of calcium
S/S: neuromuscular changes (tetany), EKG changes, parathesia-fingertips/mouth
Tx: Diet; hypocalcemic interventions, medications (phosphate binding)
The body can tolerate hyperphosphatemia fairly well BUT the accompanying hypocalcemia is a larger problem