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11 Cards in this Set

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  • Back
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p53

Tumour suppressor gene


p17


Activate DNA repair (CDK)


Halt cell cycle at G1/S


Induce apoptosis


VHL

Chromosome p3


Cysts/RCC/phaeo


Cystadenoma of epididymis


Angiomatosis eye/panc cyst


Eye/panc

Birt Hogg Dube


17


RCC (chromophobe)


Oncocytoma


Skin fibrofolliculomas


Lung cysts

p53 skin

Wilms Tumour

Beckwith Weildemann


Horsehoe


Denys Drash

Loop of Henle

dLOH - water permeable 300->1200


Thin aLOH - solute permeable


Thick aLOH - active transport 1200->150


25% Na+ absorption


Tamm-Horsfall protein

aLOH


Mucoprotein


Uromucoid


Binds to ecoli with type 1 fimbrae


Helps clear bacteria


Denosemab

RANK Ligand

Sutinib

VEGF inhibitor via Tyrosine Kinase

Temsirolimus

mTOR inhibitor

ADPKD

Most common Chromosome 16

Cystinuria

Chromosome 2