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35 Cards in this Set
- Front
- Back
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-father of medicine
-proposed the humoral theory of medicine
-first to use the words "carcinos" or "carcinoma"
-began the classification of tumors by observation |
Hippocrates |
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-believe cancer to be curable in early stages
-thought that unhealthy diet and bad climate were directly connected to ca |
Galen |
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-wrote a seven volume Epitome of Medicine
-thought that ca of breast and uterus were the most common |
Paul of Aegina |
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-physician, scientist, and philosopher
-wrote ten medical treatises
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Moses Maimonides |
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-noticed the virtual absence of cervical ca among nuns
-discovered the importance of hormonal factors in ca
-known as the 'father' of occupaitonal health |
Bernardino Ramazzini |
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-supporter of Stahl and Hofmans lymph theory of ca
-believe ca could be removed if it had not yet spread to nearby tissues |
John Hunter |
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-father of pathology
-performed autopsies to relate illness to pathological findings |
Giovanni Morgagni |
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-first to recognize the dangers of tobacco use
-published "Cautions against the immoderate use of snuff" |
John Hill |
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-english surgeon
-chimney sweeps had an occupation-related ca risk |
Pervical Pott |
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-founded in Reims, France
-1779
-moved away from city due to a widespread fear that ca was contagious |
First ca hospital |
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-first to recognize ca metastasis
-1829 |
Joseph Claude Anthelm Recamier |
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-german pathologist -published 'On the nature and structural characteristics of ca' and 'Those morbid growths... -demonstrated that ca is made up of cells -believed cells came from 'blastema' btwn normal tissues |
Johannes Muller |
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-a student of Muller
-theorized that tumors were a result of chronic irritation and ca spread in a manner similar to a liquid |
Virchow |
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-"seed and soil" theory -analyzed autopsy records of women who had breast ca and found the patterns of metastasis were not random -metastasis would only result if the seed (tumor cells) and the soil (organs) were compatible |
Steven Paget |
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-first professor of surgery at John Hopkins, harvard, and yale
-performed the radical mastectomy |
William Stewart Halsted |
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-discovered x-rays -nov 8, 1895 -radiated wifes hand |
Rontgen |
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-plane polarization of light -discovery of natural radioactivity -uranium salts phosphoresce on exposure to light -awards half of the Nobel Prize for Physics in 1903 |
Henri Becquerel |
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-first findings was to confirm with Becquerel that uranium metal was radioactive -tested pitchblende, a common ore containing uranium, lead, bismuth, and copper -more radioactive than uranium -discovered polonium on the periodic table, named after her homeland -discovered radium |
Pierre and Marie Curie |
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-injected chickens with cell free liquids obtained from chicken sarcomas and observed the formation of the sarcomas |
Francis Peyton Rous |
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-proposed the Somatic Mutation Theory of ca
-believed that ca was caused by abnormal chromosomes |
Theodore Boveri |
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What year and place was ca induced in lab animals? |
1915 Tokyo University |
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-discovered the hormones were necessary for certain ca growths -research on androgen levels and prostate ca in dogs -laid the ground work for hormone therapy |
Charles Brendon Huggins |
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-pharmacologist discovered that nitrogen mustards could be used in tx of ca -published a paper reporting nitrogen mustards as the first chemotherapy agents against hodgkins disease, lymphosarcoma, and leukemias -1946 |
Louis Goodman |
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-he proposed the DNA Provirus Hypothesis of ca |
Howard Temin |
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-they discovered the first cellular oncogene
-same gene carried by the virus described by Rous |
Varmus and Bishop |
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-was constructed and used to measure gene expression levels in plants
-now used to study ca in humans
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1995, First DNA microarray chip |
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-human epithelial and fibroblast cells were transformed into tumor cells for the first time in lab |
1999, first successful creation of tumor cells |
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Treats prostate ca by freezing cells with a metal probe |
Cryosurgery |
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-used to block the growth and spread of ca
-interfere w/ molcules involved with carcinogenesis |
Hormone Therapy Molecular-Targeted drugs |
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Anticancer drugs that eliminate ca cells |
Chemotherapy |
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Drug and type of light which combined to kill ca cells |
Photodynamic Therapy |
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Immune system fights ca or control side effects |
Biological Therapy |
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Pioneered the use of fractionated radiation therapy
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Henri coutard
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1941; Built the betatron
2 MeV - 40 MeV |
Donald A Kerst
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1929; Built the first electrostatic generator
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Robert Jeminson Van de Graff
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