Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
17 Cards in this Set
- Front
- Back
|
artherosclerosis
|
affects small arteries & arterioles and may cause downstream ischemic ds
|
|
|
monckeberg medial sclerosis
|
characterized by calcific deposits in muscular arteries in persons typically older than 50 yoa, classically a/w end stage renal ds
|
|
|
***atherosclerosis - etymology
|
from geek words for "gruel" and "hardening"
it is a disease of the intima**** TQ |
|
|
nonmodifiable major risk factors for atherosclerosis
|
- increasing age
- male gender (men 10 yrs earlier than women) - fam hx - genetic abnL |
|
|
lipoprotein classes and subclasses
|
LDL - bad
chylomicrons = very bad HDL (alpha lipoproteins) - good |
|
|
total cholesterol =
|
HDL-C + LDL-C + VLDL-CT
|
|
|
atheroma
|
fibrous cap w/ necrotic center
|
|
|
foam cells
|
oxidized LDL is ingested by macrophages through a scavenger receptor
|
|
|
patho of atherosclerosis
|
1. endothelial injury causes vasc permeability, leukocyte adhesion, thrombosis
2. accumulation of lipoproteins in the vessel wall (mainly LDL and its oxidized forms) 3. monocyte adhesion to the endothelium, followed by migration |
|
|
what is dangerous to stable plaque?
|
vulnerable plaque
|
|
|
what is a stable plaque?
|
greater thickness of fibrous cap
|
|
|
what % of coronary artery occlusion is considered critical?
|
70%
|
|
|
Frank's sign
|
diagonal ear lobe crease from tragus to rear edge of auricle
|
|
|
tombstone ST segment elevation indicative of
|
STEMI
|
|
|
want to get EKG w/in how many minutes upon arrival to ER
|
10 min
|
|
|
if pt not in pain, what do you give/not give
|
dont give NGL
do give b-blockers |
|
|
modifiable risk factors of atherosclerosis
|
- hyperlipidemia
- HTN (huge risk factor) - cig smoking - diabetes - C-RP |
