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10 Cards in this Set
- Front
- Back
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What is gnotobiotic?
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germfree
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In what ways do microbiota contribute to host defenses?
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1. development of immune system
2. aid in digestion - increase calorie availability, produce VK, 3. barrier to infections - may outcompete pathogens |
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Define virulence
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degree of pathogenicity exhibited by a pathogen, determined by virulence factors
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What are 4 broad categories of virulence factors?
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1. adherence
2. growth and colonization 3. invasiveness 4. toxicity |
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What factors are important in adherence of bacteria?
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adhesins - pili/fimbrae, capsule: have affinity to specific tissues
Eg. Neisseria - buccal tissue |
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Which bacteria have flagella?
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V. cholera
E.coli and proteus = peritrichous flagella (lots) Treponema - periplasmic flagella |
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What is a specific example of a adhesin important in UTIs?
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E.coli have Type 1 fimbrae with affinity for bladder epithelial cells
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What is a specific example of a capsular adhesin?
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Sreptococcus mutans has dextran capsul from sucrose - binds to tooth enamel = CARIES!
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What is a biofilm?
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organized bacterial communities attached to tissues or abiotic surfaces - important in catheterizations - EG. enterococcus in UTIs from catheterizations
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What are some examples of biofilms?
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Caries
Pseudomonas in CF S.aureus in catheter - nosocomial infection |
