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16 Cards in this Set

  • Front
  • Back

What percentage of fluid makes up the body?

60% for men




50% for women




Roughly 42L for the average adult

How much TBF is IC?




How much TBF is EC?

IC fluid is 60% of TBF




EC fluid is 40% of TBF

What are the components of EC space?




Where is most of the fluid?

EC can be broken down to interstitial space (IS) and intravascular space




75% of ECF is in the IS




25% is in intravascular space

What is the EC intravascular space known as?

it is know as plasma and consists of about 3L; If you count the 2L of fluid in RBCs than total blood volume is ~5L

What are crystalloid fluids?

Fluids that contain water, Na, Cl, and other electrolytes

NS
LR

DO Na and Cl freely cross into cells?

NO; they distribute evenly in EC space

How do crystalloids distribute in the body?

Extracellular space


25% remain in intravascular space and


75% distribute in the IS space

What is D5W considered?

free water; D5W is metabolized to water and CO2

In what condition to clinicians avoid D5W, why?

avoided in pt w/ neurological injury and increased ICP. Since free water can cross any membrane including the BBB water could increase ICP.

How does D5W distribute in the body?

60% to IC space




40% to EC space


-25% in intravascular space


-75% in IS space

What fluids are considered colloids?

PRBC


pooled human plasma (albumin)


dextran


hetastarch

How do colloids disperse in the fluid compartments?

colloids are too large to pass through capillary membranes; therefore, they remain primarily in the intravascular space

What is special about 25% albumin?

due to the fact its 25% albumin it creates oncotic pressure 5x normal plasma causing fluid to shift from the IS space into intravascular space.

What has hetastarch and dextran been associated with?

coagulopathy and kidney impairement.




Hetastarch is also associated w/ increased mortality in critically ill pts

How much fluid should be given for maintenance?

1500 mg for first 20 kg then 20 ml/kg over 20 kg

What is a typical maintenance fluid?




What about pts who have neurological injuries or brain trauma?

D5W/0.45% NS w/ 20-40 mEq KCl




No D5W for brain injuries