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7 Cards in this Set

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Conceptul medical de sanatate si boala.
Sanatatea: capac. de a ment. const. parametri biofizici, biochimici si fctionali.
OMS: "stare optima fizica, mentala si sociala a org. um."
org uman: unitatte antientropica autoreglat prin feedbac-feedbefore, neuroendocrinoumoral. (antientr.=inteligenta). homeostazie: biostaza, psihostaza, sociostaza.
Boala: expresia periclitari mec de reglare ale homeostaziei. (abatere de la norm. in fct. de varsta sex etc.) ! este rezultatnt perturb. interschimb. info. dintre dif. sist. funct, intre org. si mediu, precum si a suport. E
cele 6 caracterisitici ai boli
1) Boala reprezinta tulburarea mecanismelor de reglare ale homst.; tulb. circuitelor cibernetice si a celor neuroendocrinoumr.
2) Boala e det. cauzal [fact. cauz. determinanti, fact. adjuvanti, fact oblig patogeni, fact. cond. patogeni] 3) Boala det aparitia unor reactii adaptative,si unor reactii patologice [febra, poliglob, leucocitoza] 4) Boala det. scad. rand biologic si energetic [vulnerab]5) B. dimin. potent de munca si implicit integr. sociala 6) B. afecteaza org. in ansambl.
criterii de calsificarea bolilor
1) anatomic (organ sau sist lezat)
2) semiologic (grav. clinica)[acut,supraacut..]
3)etiologic (traumatice, infect, metab.)
4) momnetul aparititiei in onotgeneza (ereditar, congenital, dombandit)
5) criteriu ponderii dintre struct genet. si mediu [genetice, paratipice(sindr. de strivire, intoxic), boli multifact]
perioadele de evoltutie ale bolilor
1) Perioada de latenta(secunde-ani)-debut. fiziopat.
2)P prodromala/invazie (simptome necaracteristice)-debut clinic.
3) perioada de stare(manifest caract-incep. declin)[reactivitate, constitutia, teren, predispozitia]
4)P. de declin (vindecare, croniczare, moarte)
Sanogeneza: blocare, eliminare neutralizare
filtru biologic: bareiere externe(tegument, conjunctiva, mocouasa); bariere interne(mebrana, organ, SNC)
eliminare: tuse,stranut, voma,diaree,clipit, hiperlacrim
neutralizare: conjugare(hidrofob-hidrofil, bila urina); inactivare(reducere, oxid, proteoliza, dezaminare); pt. ag. bio: inflamaite (degradare, limitare)
Sanogeneza: restruct. imunologica
crest. rezist. org. dat. experientei castigate prin boala-nou teren.
nivel enzimatic: crestera activ. hidrolitice proteazice- degrad. ag. patogeni
nivel ligand specif. imun: sintez de recept. pe cel B,T fata de Ag; produc. de imunohormoni
Sanogeneza: regenerare
refacere si inlocoire a cel. si tes uzate.
fiziologica;
reparatoie (nervos, miocard, cartilag, musc. f putin; sange masiv; tes conj: cicatrizare) nu e regener. identica.
apoptoza (activ. endonucleaze endogene): embriogeneza, involutie hormon dependenta, moartea cel. imune dupa depletia citokinelor.; apopt. normala (imbatr. cel.), apopt abuziva (ex. diminuare unor fact. de crestere), apopt. aberanta (senscenta)