• Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/18

Click to flip

18 Cards in this Set

  • Front
  • Back
  • 3rd side (hint)
Action and use of Finasteride?
5alpha-reductase inhibitor (decreased conversion of testosterone to dihydrotestosterone). Used for BPH and baldness
Action and use of Flutamide?
nonsteroidal competitive inhibitor of androgens at the testosterone receptor. Used in prostate ca
Action and use of ketoconazole?
inhibit steroid synth; used in polycystic ovarian syndrome to prevent hirsutism
Action and use of spironolactone?
inhibit steroid synth; used in polycystic ovarian syndrome to prevent hirsutism
MOA of sildenafil/vardenafil?
inhibit cGMP phosphodiesterase causing increased cGMP, smooth musc relax in corpus cavernosum, increased blood flow and erection
Use of sildenafil/vardenafil?
treatment of erectile dysfxn
Toxicity of sildenafil/vardenafil?
HA, flushing, dyspepsia, blue-green color vision. Risk of life-threatening hypotension in pts taking nitrates
MOA of leuprolide?
GnRH analog w/agonist properties when used in pulsatile fashion; antagonist properties when used in continuous fashion (continous causes transient initial burst of LH and FSH)
Use of leuprolide?
infertility (pulsatile), prostate ca (continuous w/flutamide), unterine fibroids
Toxicity of leuprolide?
antiandrogen, N/V
MOA of clomiphene?
partial agonist at estrogen receptors in pituitary gland. Prevents nrm feedback inhibition and increases release of LH and FSH from pituitary…stimulates ovulation
Use of clomiphene?
tx of infertility
Toxicity of clomiphene?
hot flashes, ovarian enlargement, multiple simultaneous pregnancies, visual disturbances
MOA of mifepristone (ru-486)?
competitive inhibitor of progestins at progesterone receptors
Use of mifepristone?
abortifactant (prevents implantation)
None
Toxicity of mifepristone (ru-486)?
heavy bleeding, GI effects (N/V, anorexia), ab pain
Advantages of oral contraceptives (5)?
reliable, decreased risk of endometrial/ovarian ca, decreased risk ectopic preg, decreased pelvic infxn, regulation of menses
Disadvantages of oral contraception (5)?
taken daily, no STD protection, increased triglycerides, depression/wt gain/nausea/HTN, hypercoaguable state