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24 Cards in this Set
- Front
- Back
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Haloperidol, trifluoperazine, fluphenazine, Thioridazine, chlorpromazine (-azines + Haloperidol)
What class of Drugs? |
Typical antipsychotics
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MOA of Typical Antipsychotics
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Block D2
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High potency Typical antipsychotics: Trifluoperazine, fluphenazine, haloperidol
Have what type of SE? |
Extrapyramidal
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Low potency Typical antipsychotics: Chlorpromazine, Thioridazine
Have what type of SE |
Anticholinergic
Antihistamine Alpha blockade |
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SE of chlorpromazine
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corneal deposits
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SE of Thioridazine
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Retinal deposits
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Olanzapine, Clozapine, Quetiapine, Risperidone, Aripiprazole, Ziprasidone
What class of drugs? |
Atypical antipsychotics
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Atypical antipsychotic MOA
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Block dopamine, serotonin, histamine, alpha recepotrs
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Atypical antipsychotics that cause significant weight gain
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Olanzapine
Clozapine |
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Atypical antipsychotic that causes agranulocytosis (monitor WBCs)
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Clozapine
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Atypical antipsychotic that causes prolonged QT interval
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Ziprasidone
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Amitriptyline, nortriptyline
Imipramine, Clomipramine, Desipramine Doxepin, amoxapine What class of durgs? |
TCA
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TCA MOA
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Block reuptake of NE and serotonin
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TCA SE
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Sedation, alpha blocking (orthostatic hypotension & reflex tachycardia), anticholinergic,
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TCA toxicity and TX
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Convulsions, coma, cardiotoxicity
Sodium bicarbonate |
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Fluoxetine, Paroxetine
Setraline Citalopram What class of drugs? |
SSRIs
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SSRI MOA
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Block reuptake of serotonin
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SSRI SE and TX
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Sexual dysfunction (loss of libido), weight gain, insomnia, Serotonin Syndrome
Cyproheptadine (for Serotonin Syndrome) |
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Venlafaxine, Duloxetine
What class of drugs? |
SNRIs
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SNRI MOA
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Block reuptake of serotonin and NE
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SNRI SE
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Increase BP, stimulant effects, sedation
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Tranylcypromine
Isocarboxazid Phenelzine Selegiline What class of drugs? |
MAOIs (Selegiline is selective MAO-B I)
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MAOI MOA
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Inhibit MAO to increase levels of serotonin, NE, dopamine
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MAOI Toxicity
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Hypertensive crisis (when ingest with tyramine)
Serotonin Syndrome |
