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21 Cards in this Set

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  • Back
54. Idiopathic Hypersomnia (IH)?
a. Rare disorder characterized by excessive daytime sleepiness, prolonged nocturnal sleep episodes, and frequent irresistible urges to nap.
b. IH can be mild or as debilitating as narcolepsy.
55. Kleine-Levin syndrome?
a. A rare disorder characterized by recurrent hypersomnia w/episodes of daytime sleepiness w/hyperphagia, hypersexuality, and aggression.
56. Circadian Rhythm Sleep Disorders?
a. Circadian rhythm sleep disorders are caused by either intrinsic defects in the circadian pacemaker or impaired entrainment (absence of light or other time-signalling stimuli).
b. Subtypes include delayed sleep phase disorder, shift-work disorder, and jet lag disorder.
57. Sx of Circadian Rhythm Sleep Disorder?
a. Excessive daytime sleepiness
b. Insomnia
c. Sleep inertia
d. Headaches
e. Difficulty concentrating
f. ↑ reaction times and frequent performance errors.
g. Irritability
h. Waking up at inappropriate times.
58. What area of the brain coordinates 24-hour circadian rhythmicity?
a. The suprachiasmatic nucleus (SCN) in the hypothalamus.
59. Parasomnias?
a. Abnormal behaviours or experiences that occur during sleep and are often associated w/sleep disruption.
b. Sx may include abnormal movements, emotions, dreams, and autonomic activity.
c. Common in childhood and adolescence.
60. Sleepwalking Features?
a. Characterized by simple to complex behaviours that are initiated during slow-wave sleep and result in walking during sleep.
b. Behaviours may include sitting up in bed, eating, and in some cases “escaping” outdoors.
c. Eyes are usually open w/a “glassy look”.
d. Difficulty arousing the sleepwalker during an episode.
e. Confusion on awakening, amnesia for episode.
f. Episodes usually end w/pts returning to bed or awakening confused and disoriented.
g. Rare cases associated w/violent behaviour, especially upon forced awakening.
61. Epidemiology of sleepwalking?
a. 1-4% of adults.
b. 10-20% in children and adolescents.
c. Occurs more often in children w/obstructive sleep apnea.
62. Risk factors for Sleepwalking?
a. Sleep deprivation
b. Irregular sleep schedules.
c. Stress
d. Hyperthyroidism
e. Seizures
f. Migraines
g. Meds, including sedative/hypnotics, lithium, and anticholinergics.
h. Magnesium deficiency.
63. Tx of sleep walking?
a. Pts benefit from addressing precipitating factors, ensuring a safe environment, and proper sleep hygiene.
b. Refractory cases may respond to clonazepam other benzodiazepine receptor agonist, or TCA.
64. Sleep Terrors?
a. Episodes or sudden arousal w/screaming from slow-wave sleep in what appears to be a state of complete terror.
b. Sympathetic hyperactivation, including tachycardia, tachypnea, diaphoresis, and ↑ muscle tone.
c. After episode, pts usually return to sleep w/out awakening.
d. Usually amnesic about episode.
e. Confused and disoriented upon forced awakening
f. In rare cases, awakening elicits aggressive behaviour.
65. Epidemiology of sleep terrors?
a. 1-6% of children
b. 1-2% of adults.
c. High comorbidity w/sleepwalking.
66. Risk factors for Sleep Terrors?
a. Fever
b. Nocturnal asthma
c. GERD
d. Sleep deprivation
e. CNS-stimulating meds.
f. Other sleep disorders such as sleep apnea.
67. Tx of sleep terrors?
a. Reassurance that the condition is benign and self-limited.
b. Consider a low-dose, short-acting BZD (clonazepam, diazepam) in adults w/refractory cases.
c. Sleep hygiene, psychotherapy.
68. Nightmare Disorder?
a. Recurrent frightening dreams that tend to terminate in awakening w/vivid recall.
b. No confusion or disorientation upon awakening.
c. Can -> significant distress and anxiety.
69. In what condition are nightmares seen in at least 50% of pts?
a. PTSD.
70. Tx of Nightmare Disorder?
a. Imagery rehearsal therapy (IRT) involves the use of mental imagery to modify the outcome of a recurrent nightmare, writing down the improved outcome, and then mentally rehearsing it in a relaxed state.
b. Severe cases may benefit from use of antidepressants.
71. REM Sleep Behaviour Disorder (RBD) is characterized by?
a. Muscle atonia during REM sleep and complex motor activity associated w/dream mentation (dream enactment).
b. Dream-enacting behaviours, which may include:
1. Sleep talking
2. Yelling
3. Limb jerking
4. Walking and/or running.
5. Punching and/or other violent behaviour.
c. Presenting complain is often violent behaviours during sleep resulting in injury to the pt and/or the bed partner.
72. Risk factors for REM Sleep Behaviour Disorder (RBD)?
a. Older age, generally between 60-70
b. Psychiatric meds such as TCAs, SSRIs, and MAOIs.
c. Narcolepsy
d. Brain Stem lesions
e. Dementias such as olivopontocerebellar atrophy and diffuse Lewy body disease.
73. Tx for REM Sleep Behaviour Disorder (RBD)?
a. Clonazepam is efficacious in 90% of pts.
b. Other agents that may be helpful include imipramine (Tofranil), carbamazepine (Tegretol), pramipexole (Mirapex-potentiates antidepressants), or levodopa.
c. Ensure environmental safety such as removing potentially dangerous objects from the bedroom and sleeping on the ground until behaviours can be managed effectively.
74. Complete
74. Complete