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20 Cards in this Set

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1. 2 Main subdivisions of Anorexia Nervosa?
1. Restrictive subtype
2. Binge-eating/purging type
2. Restrictive type of Anorexia Nervosa?
a. Has not regularly engaged in binge-eating or purging behaviour.
b. Often w/OCPD traits
3. Binge-eating/purging type?
a. Eat in binges followed by self-induced vomiting, using laxatives, excessively exercising, and/or using diuretics.
4. DSM diagnosis of Anorexia Nervosa?
a. Refusal to maintain a minimally normal body wt. for one’s age and height (< 85% of ideal body weight or BMI <17.5
b. Intense fear of gaining weight or becoming fat
c. Disturbed body image, undue influence of weight or shape on self-evaluation, or denial of the seriousness of the current low body weight.
d. Amenorrhea in post-menarchal females (ie, absence of at least 3 consecutive menstrual cycles.
5. Physical manifestations of Anorexia Nervosa?
a. Amenorrhea
b. Cold intolerance/hypothermia
c. Hypotension, especially orthostasis
d. Bradycardia
e. Arrhythmia
f. Acute coronary syndrome
g. Cardiomyopathy
h. Mitral valve prolapse
i. Constipation
j. Lanugo hair
k. Alopecia
l. Oedema
m. Dehydration
n. Peripheral neuropathy
o. Seizures
p. Hypothyroidism
q. Osteopenia/osteoporosis.
6. Lab findings in Anorexia Nervosa?
a. Hyponatremia, hypochloremic hypokalemic alkalosis (if vomiting)
b. Arrhythmia (especially QTc prolongation)
c. Hypercholesterolemia
d. Transaminitis
e. Leukopenia
f. Anaemia (normocytic normochromic)
g. ↑ BUN
h. ↑ GH
i. ↑ Cortisol
j. Reduced LH and FSH.
k. Reduced sex steroid hormones (oestrogen and testosterone
l. Hypothyroidism
m. Hypoglycaemia
7. How is Bulimia distinguished from Anorexia?
a. Both may binge and purge.
b. Anorexia Nervosa involves LOW BODY EIGHT, and this distinguishes it from bulimia.
8. Classic example of Anorexia Nervosa?
a. An extremely thin amenorrheic teenage girl whose mother says she eats very little, does aerobics for 2 hrs a day, and ritualistically does 400 sit-ups every day (500 if she has “overeaten”).
9. What % of Anorexia Nervosa pts are female?
a. 90-95%.
b. Prevalence is 1%.
10. Age of onset for Anorexia Nervosa?
a. Bimodal:
1. 13-14: hormonal influences.
2. 17-18: environmental influences.
11. Where is Anorexia Nervosa more common?
a. In industrialized countries where food is abundant and a thin body is ideal.
12. Appetite in Anorexia versus Major Depressive Disorder?
a. Anorexia: pts have good appetite but starve themselves due to distorted body image. They are often quite preoccupied w/food, preparing it for others, etc, but do not eat it themselves.
b. Major Depressive Disorder: Pts usually have poor appetite, which -> weight loss. These pts have no interest in food.
13. Refeeding syndrome?
a. Occurs when severely malnourished pts are refed too quickly.
b. Look for fluid retention and ↓ levels of phosphorous, mg, and Ca.
c. Complications include:
1. Arrhythmias
2. Respiratory failure
3. Delirium
4. Seizures
d. Replace electrolytes and slow the feedings.
14. Prognosis of Anorexia Nervosa?
a. Mortality rate is cumulative, and approximately 10% die due to starvation, Suicide, or cardiac failure.
b. Rates of suicide are approximately 57x higher than normal.
15. Tx of Anorexia Nervosa?
a. Food is the best medicine!!!
b. Pts may be tx’d as outpts unless they are more than 20% below ideal body wt or if there are serious medical or psychiatric complications, in which case they should be hospitalized or supervised refeeding.
c. Tx involves behavioural therapy, family therapy (eg, Maudsley approach), and supervised weight-gain programs.
16. Rx Tx for Anorexia Nervosa?
a. SSRIs have not been effective, which is believed to be due to inadequate dietary intake of tryptophan, the precursor of serotonin.
b. Low-dose second-gen antipsychotics may tx excessive preoccupation w/wt. and food in addition to independently promoting wt. gain.
c. BZDs may also be administered prior to meals to reduce preprandial anxiety.
17. 2 subcategories of Bulimia?
1. Purging type: Involves vomiting, laxatives, enemas, or diuretics.
2. Non-purging type: Involves excessive exercise or fasting.
18. DSM diagnosis of Bulimia?
a. Recurrent episodes of binge eating
b. Recurrent, inappropriate attempts to compensate for overeating and prevent wt. gain (such as laxative abuse, vomiting, diuretics, or excessive exercise.
c. The binge eating and compensatory behaviours occur at least 2x a wk for 3 months.
d. Perception of self-worth is excessively influenced by body weight and shape.
19. Physical manifestation of Bulimia Nervosa?
a. Salivary gland enlargement (sialadenosis)
b. Dental erosion/caries
c. Calluses/abrasions on dorsum of hand (“Russell’s sign” from self-induced vomiting)
d. Petechiae
e. Peripheral Edema
f. Aspiration
20. Lab findings in Bulimia Nervosa?
a. Hypochloremia hypokalemia alkalosis
b. Metabolic acidosis (laxative abuse)
c. ↑ bicarb (compensation)
d. Hypernatremia
e. ↑ BUN
f. ↑ Amylase
g. Altered thyroid hormone and cortisol homeostasis
h. Esophagitis.