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24 Cards in this Set

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clonidine (drug class)?
central acting alpha-2 agonist
clonidine (mechanism)?
decrease central adrenergic outflow
clonidine (indication)
use to tx HTN, espeically w/renal dz due to no decrease in blood flow to kidney
alpha
methyldopa (drug class)?-central acting alpha-2 agonist
alpha
methyldopa (mechanism)?-decrease adrenergic outflow
alpha methyldopa (indication)-
use for tx HTN especially w/renal dz (doesn't decrease blood flow to kidney)
good way to tx HTN in setting of renal dz?
central alpha-2 agonists = drugs that dont decrease flow to kidneys (clonididne, alpha-methyldopa)
phenoxybenzamine (drug class)?
Irreversible nonselective alpha adrenergic blocker
phenoxybenzamine (indication)
use for pheochromocytoma before removal b/c high levels of catecholimens won't overcome irreversible block (also long t-half)
phentolamine (drug class)?
nonselective alpha blocker
phentolamine (indication)
used for pts on MAO inhibitors who eat tyramine containing foods
toxicity of nonselective alpha blockers?
orthostatic hypotension and reflexive tachycardia
drug class of all the following: doxazosin, terazosin, prazosin?
alpha-1 selective alpha blockers
alpha
1 selective alpha blockers (indications) - tx HTN, urinary retention in BPH
alpha
1 selective alpha blockers (toxicity)- 1st dose orthostatic HTN, dizziness, headache"
doxazosin(indications)
tx HTN, urinary retention in BPH
terazosin(indications)
tx HTN, urinary retention in BPH
prazosin(indications)
tx HTN, urinary retention in BPH
doxazosin(toxicity)
1st dose orthostatic HTN, dizziness, headache"
terazosin(toxicity)
1st dose orthostatic HTN, dizziness, headache"
prazosin(toxicity)
1st dose orthostatic HTN, dizziness, headache"
mirtazapine (drug class)?
alpha-2 selective alpha blocker
mirtazapine (indication)
use for tx of depression
mirtazapine (toxicity):
sedation, increased cholesterol, increased appetite