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72 Cards in this Set

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motitlity causes swarming on agar, urease positive and produces truvite stones
proteus
congenital infection making you like helen keller (deaf and catarcts) plus a bad heart (PDA and pulmonary stenosis, small head
congenital german measles (rubella) - toga virus (ss+ RNA) like eastern and western equine
ECSTaTiC bacteriostatics
erythromycin, Clindamycin, SUlfamethoxazole, Trimethoprim, Tetracylines, Chloramphenicol
Very Finely Proficient At Cell Murder
Vanc, FluoroQs, Penicillin, Aminoglycosides, Cephalosporins, Metronidazole
IV cillin
G
oral cillin
V
methcillin , nafcillin, dicloxacillin are all beta-lactamase resistant because
bulk R group
Amoxacillin has greater oral bioavailability than
Ampicillin
penicillins with an A AMp and AmoralOx are
just wider spectrum penicillins remember amox is more orally bioavailable
Ampicillins and amox extend spectrum into
gram negative rod range, (H flu, E coli, Proteus salmonella
spectrum of plain ole penicillin
Gram Positive, spirochetes, ad Gram negative Cocci
Ticarcillin carbenicillin and pipercillin are specialized to kill
pseudomonas and other Gram neg rods
Ticarcillin carbenicillin and pipercillin used with
beta-lactamase inhibitors (clav, tazo sulbact)
1st gen ceph
cefazolin cephalexin
1st gen ceph for
cefazolin cephalexin for gram positive cooci Proteus Ecoli Klebs PEcK
Cefazolin cephalexin for
proteus ecoli klebs PEcK
PEcK
Cefazolin Cefelexin treats Proteus Ecoli Klebs
2nd genHEN Ceph
cefaclor cefuroxime cefoxitin
cefaclor cefuroxime cefoxitin are 2nd genHEN Ceph that treat
PEcK and HEN (H.Flu, Enterobacter aerogenes, Neiserria)
PEcK and HEN (H.Flu, Enterobacter aerogenes, Neiserria)
cefaclor cefuroxime cefoxitin are 2nd genHEN Ceph that trea
na,e the third gen cephs
ceftriaxone, cefotaxime, ceftazadine
ceftriaxone (meningitis), cefotaxime, ceftazadine (pseudo)
the third gen cephs
gang busters against gram negative rods
ceftriaxone, cefotaxime, ceftazadine
what drug increases kidney toxicity with aminoglycosides
Cephs
binds PBP3 a monobactan
Azetreonam
monobactam binds PCB-3 is not cross alergenic with pennicillin and has wha spec
Azetreonam has the spec of Gram Neg rods Klebs Pseudo, Serratia
no activity against gram positives or anaerobes
Azetreonam a monobactam
Administered with cilastin to decrease inactivation of renal tubules
Imipinem
imipenem administered with
cilastin
drug of choice for enterobacter
cilastin/IMipenem
reduced risk of seizure and and stable to dihydropeptidase one
meropenem
pretreat with antihistamine
vancomycin preatreatment to avoid red man syndrome
Vanc MOA
inhibits cell wall mucopeptide formation by binding to D-ala-Dala
name the aminoglycosisdes
tobra, genta amika and strepto
MOA of aminoglycosides30
inhibits formation of the initiation complex and causes misreading of mRNA
aminoglycosides are ineffective against
anaerobes
aminoglycoside for bowel surgery
neomycin
neophrotoxic especially used with cephalosporins
aminoglycosides which inhibit the formation of the initiation complex and cause misreading of mRNA
prevent attachment of aminoacyl-tRNA
Tetracycline 30
tetracycline 30 MOA
prevent attachment to the aminoacyl-tRNA
tetracycline that can be given to renal failure patient
Doxy which is fecally eliminated
23 0f the 50
Macrolides (clarithro, Azithro, Erythro)
23 of the 50 Macrolides MOA
inhibit protein synthesis by blocking translocation
inhibit protein synthesis by blocking translocation
23 of the 50 Macrolides MOA
strep infection but allergic to penicillin
givem a 23 of the 50 macro to block translocation
acute cholestatic hepatitis side effect of what antibiotis
23 of the 50 macro blocking translocation
inhibits 50s peptidyl transferase
chloramphenical pan
chloramphenicol pan MOA
inhibits 50s peptidyl transferase
why does the peptidyl transferase chloramphenicol pan cause grey baby syndrome
baby aint got no UDP-glucourynyl transferase
blocks peptide bond formation at the 50 s
clindalinda blocks peptide bond formations
clindalinda blocks
peptide bond formation
toxicity of clinda linda who blocks peptide bond formation
C. Diff
treats anaerobes above the diaphragm
clindalinda blocks eptide bond formation
Pteridine + PABA
Dihydropteroic acid thanks to its synthase
sulfanomides block
Pteridine + PABA --> Dihydropteroic acid (he enzyme is the same synthase
Pteridine + PABA --> Dihydropteroic acid (he enzyme is the same synthase) is blocked by
sulfanomides
Dihydrofolic acid becomes
THF via its own personal reductase
Dihydrofolic acid becomes THF via its own personal reductase that can be blocked by
Trimethoprim Pyrimethamine
Trimethoprim Pyrimethamine MOA
Dihydrofolic acid becomes THF via its own personal reductase that can be blocked by
kernicterus in infants because displaced other drugs off albumin
sulfanomides
inhibits bacterial dihydrofolate reductase
TMP
thiazides, acetozolamide or furosemide
should not be given to one with sulfa allergies
should not be given to one with sulfa allergies
thiazides, acetozolamide or furosemide
FluoroQs clinical use is limited too
gram neg rods of Urinary and GI tract
cationic basic proteins that act like detergeants
polymixins
polymixins are
cationic basic proteins that act like detergents
clinical use of the cat-base polymix
resistant gram negs (used in theyer martin media for this too)
prophylaxis of M. avium
Azithro
second line therapy for TB
cycloserine
moa of INH (Isoniazid)
decrease mycolic acid synth
different INH half lifes depend on
acetylating speed
delays resistance to dapsone when used for leprosy
rifampin