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38 Cards in this Set
- Front
- Back
no cell wall
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mycoplasma
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2 gram + coccus
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staph/ strep
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gram + rods (5)
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clostridium
corynebacterium bacillus listeria mycobact. |
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gram + branching filamentous (2)
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nocardia (weakly acid fast)
actinomyces |
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gram - pleomorphic
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ricketssiae
chlamydia (giemsa stain) |
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spiral, gram -
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spirochetes (leptospira, borrelia, treponema)
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everything else ?
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gram - enteric
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Gram stain limitations -- "These Rascals May Microscopically Lack Color "
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T- treponema - dark field
R- rickettsia - intracellular parasite M- mycobacteria- acid fast M - mycoplasma - no cell wall L- legionella - silver stain C - chalmydia - no muramic acid in cell wall |
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obligate aerobes - Nagging Pests Must Breathe
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N- nocardia
P- pseudomonas M- mycobacteria tb B- bacillus |
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P. AERuginosa is an AERobe
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seen in burn wounds, nosocomial pneumonia also in c.f. patients
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Obligate anaerobes --> Anaerobes - "Cant Breathe Air"
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C- clostridium
B- bacteroides A- actinomyces - foul smelling, and produce gas in tissue |
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what drugs are ineffective against anaerobes?
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aminglycosides --> require 02 dependt transporter to enter the cell
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Intracellular bugs - Obligate inctracellular
--> Stay inside cells when its "Really Cold" |
R- rickettsia
C- chlamydia --> stay inside b/c cannot make own atp |
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Facultative intracellular - "Some Nasty Bugs May Live FacultativeLY"
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S- salmonella
N- neisseria B- brucella M- mycobacerium L- listeria F- francisella L- legionella Y- yersinia |
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Quellung = ?
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Quellung = "Swellung"
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which bugs have capsules? "Some Nasties Have Kapsules"
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S- strep. pneumo
N- neisseria meng. H- haemophilus K- Klebsiella "Some Nasties Have Kapsules" |
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Urease positive bugs..."Particular Kinds Have Urease"
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P- proteus
K- klebsiella H- H.pylori U- ureaplasma --> "Particular Kinds Have Urease" |
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staph. aureus pigment ? Aureus means what in latin?
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Aureus = gold in latin
--> yellow pigment |
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how do superantigens work?
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bind drctly to mhc2 and t-cell receptor simultaneously --> activating large amounts of t-cells --> causing massive release of IFN-gamma y IL-2
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S. aureus exotoxin?
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tsst-1 superantigen --> toxic shock syndrome
- exfoliatin --> staph. scaled skin syndrome |
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c.diptheriae toxin ?
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inactivates elongation factor 2 --> pharyngitis and pseudomembrane in throat
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lsogeny --> genes that are encoded in a lysogenic package
--> ABCDE |
A- shigA-like toxin
B- botulinum toxin C- cholera toxin D- diptheria E- erythrogenic toxin of S. pyogenes |
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Gram + --> Cooci --> Catalase + in clusters --> coagulase + ?
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S. aureus
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Gram + --> cocci --> Catalase + in clusters (Staphylococcus) --> coagulase (-) --> novobiocin sensitive (?) ; novobiocin resistant (?)
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novobiocin sensitive --> S. epidermidis
novobiocin resistant --> S. saprophyticus |
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Gram + --> Cocci ---> Catalase (-) in chains ?
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Streptococcus
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Gram + --> cocci --> Catalase (-) --> partial hemolysis (=alpha hemolytic, green) --> Capsule (+ quellung) ?
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Strep Pneumoniae
- optochin sensitive, bile soluble |
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Gram + --> cocci --> Catalase ((-) strep) --> partial hemolysis (alpha hemolytic, green) --> negative quellung (no capsule), optochin resistant?
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strep. viridans
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gram + cocci, Catalase (-), Beta hemolytic (clear hemolysis) , bacitracin sensitive --> ?
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Group A strep --> Strep Pyogenes
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gram + cocci, catalase (-), Beta hemolytic (clear hemolysis) , bacitracin resistant --?
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Group B. Strep --> S. agalactiae
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Gram + cocci, catalase (-), Gamma hemolytic (no hemolysis) ?
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Enterococcus (E. faecalis)
Peptostreptococcus (anaerobe) |
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Streptococci stain id? "B-BRAS"
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B- Bacitracin
B- group B strep are R- resistant A- group A strep are S- sensitive |
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why does staph make catalase?
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b/c staph have more STAFF --> make more catalase
-catalase --> degrades h202 and is product of pmns |
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Staph. aureus
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-protein A virulence factor, binds Fc-IgG
- tsst superantigen binds MCH2/Tcell receptor - inflammatory disease - toxin disease (tsst-1 toxin) - rapid food poisoning from entertoxins - mrsa |
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staph. aureus
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acute bacterial endocarditis, osteomyelitis
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Staph. epidermidis
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- infects prosthetic devices/ catheters
- normal skin flora - contaminates blood cultures |
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Strep. Pneumo --> "S.Penumoniae MOPS are Most OPtochin Sensitive"
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M-meningitis
O- otitis media in kids P- pneumonia S- sinusitis --> rusty sputum, sepsis in sickle cell anemia, splenectomy |
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Viridans group strep
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-alpha hemolytic
- mutans = dental caries - S. Sanguis (blood) --> subacute bacterial endocarditis (lots of blood in the heart) |
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Viridans lives in the mouth b/c?
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Viridans lives in the mouth b/c its not afraid OF-THE-CHIN (optochin resistant)
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