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37 Cards in this Set
- Front
- Back
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Bugs that do not Gram stain well:
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Treponema - too thin
Rickettsia - intracellular Mycobacteria - hi lipid Mycoplasma - no cell wall Legionella - intracellular Chlamydia - intracellular, no muramic acid |
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H. influenzae, special culture
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Chocolate agar
- factor V (NAD) - factor X (hematin) |
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N. gonorrhoeae, special culture
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Thayer-Martin media
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B. pertussis, special culture
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Bordet-Gengou (potato) agar
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C. diptheriae, special culture
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Tellurite plate
Loffler's media |
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M. tuberculosis, special culture
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Lowenstein-Jensen agar
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M. pneumoniae, special culture
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Eaton's agar
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E. coli, special culture
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Eosin-methylene blue (EMB) agar
(blue-black colonies w/ metallic sheen) |
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Lactose-fermenting enterics, special culture
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MacConkey's agar (pink colonies)
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Legionella, special culture
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Charcoal yeast extract agar
(buffered w/ iron and cysteine) |
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Fungi, special culture
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Sabouraud's augar
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Obligate aerobes (4)
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Nocardia
Pseduomonas AERuginosa Mycobacterium tuberculosis (lung apex) Bacillus (Nagging Pests Must Breath) |
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Obligate anaerobes (3)
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Clostridium
Bacteroides Actinomyces (Can't Breathe Air) (AminOglycosides ineffective, need O2 for entry) |
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Obligate intracellular (2)
(can't make their own ATP) |
Rickettsia
Chlamydia (Stay inside when its Really Cold) |
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Facultative intracellular (8)
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Salmonella
Nisseria Brucella Mycobacterium Listeria Franciscella Legoinella Yersinia (Some Nasty Bugs May Live FacultativeLY) |
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Encapsulated bacteria (4)
(possitive quellung rxn, swell) (antiphagocytic virulence factor) |
Strep pneumo
Neisseria meningitidis Hameophilus influenza Klebsiella pneumoniae |
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Urease positive (4)
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Proteus
Klebsiella H. pylori Ureaplasma (Particular Kinds Have Urease) |
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Pigment producing microbes (3)
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S. aureus - yellow
Pseudomonas aeruginosa - bluegreen Serratia marcescens - red |
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Protein A, virulence factor
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S. aureus
bind Fc pt of Ig |
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IgA protease, virulence factor
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S. pneumo
H. influenzae Neisseria |
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M protein
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Group A strep
prevent phagocytosis |
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Superantigen, exotoxin
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binds MHC II & TCR
stimulate release of IFN-gamma & IL-2 |
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S. aureus superantigen, exotoxin
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TSST-1 - toxic shock syndrome
Enterotoxins - food poisioning Exfoliatin - SSSS |
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S. pyogenes superantigen, exotoxin
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Scarlet fever erythrogenic toxin
causes toxic shock like syndrome |
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ADP ribosylating A-B toxin, exotoxin
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B - binding, enables endocytosis
A - active, ADP ribosylation |
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Corynebacterium diptheriae
ADP ribosylating A-B toxin, exotoxin |
Inactivates EF-2
(like pseudomonas exotoxin A) causes pharyngitis and pseudomembrane |
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Vibrio cholerae
ADP ribosylating A-B toxin, exotoxin |
stimulated adenylate cyclase
pumps Cl out, stops Na in rice water diarrhea |
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E. coli
ADP ribosylating A-B toxin, exotoxin |
Heat labile - stimulates adenyl cyclase
Heat stable - stimulates guanyl cyclase Both cause watery diarrhea (labile like the Air, stable like the Ground) |
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Bordetella pertussus
ADP ribosylating A-B toxin, exotoxin |
Stimulates adenyl cyclase, inhibits Gi
whooping cough |
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Clostridium perfringes, other exotoxin
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alpha - gas gangrene
double zone of hemolysis on blood agar |
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Clostridium tetani, other exotoxin
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blocks release of GABA and glycine
causes lockjaw |
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Clostridium botulinum, other exotoxin
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blocks release of acetylcholine
CNS paralysis honey - floppy baby |
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Bacillus anthracis, other exotoxin
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edema factor is an adenylate cyclase
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Shigella, other exotoxin
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Shiga toxin (also from E. coli O157:H7)
cleaves rRNA (60S) HUS - from cytokine release |
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Strep pyogenes, other exotoxin
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Streptolysin O - hemolysin
antigen for ASO antibody - dx rheumatic fever |
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Micro cAMP inducers
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Vibrio cholerae - turns on on (Gs)
B. Pertussus - turns off off (Gi) E. Coli - heat labile toxin Bacillus anthracis - edema factor |
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Lysogenic toxin microbes
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ShigA like toxin
Botulinum Cholera Diphtheria Erythrogenic - from Strep pyogenes |
