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7 Cards in this Set
- Front
- Back
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penicillin/ cephalosporins
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b-lactamase cleavage of b-lactam ring
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aminoglycosides
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MODIFICATION via acetylation, adenylation, phosphorylation
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vancomycin
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D ala replaced w/ D lac. Decreased affinity
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chloramphenicol
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modification via acetlyation
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macrolides
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methylation of rRNAnear erythromycin's ribosome-binding site
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tetracycline
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decreased uptake of increased transport out of cell
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sulfonamides
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altered enz (bact DHF synthetase), dec uptake, increased PABA syn
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