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48 Cards in this Set

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  • Back
  • 3rd side (hint)
anisocytosis refers to
cells of varied size
cells of varied shape
polka dots are a shape
basophils granules contain (3)
SRS-A (slow reacting substance of anaphylaxis)
(give 3 items)
eosionphil granules contain
histaminase, arlysulfatase
(give 2 items)
mast cell granules contain
heparin, histamine,
eosinophil chemotactic factors (ECFs)
(give 3 items)
causes of eosinophilia
Some feel allergic to the NAACP

Collagen vascular disease
neutrophil granules contain
lactoferrin, myeloperoxidase, lysozyme
(give 3 items)
B lymphocytes mature here
what matures in the Bone marrow and migrates to lymphoid tissue
T lymphocytes mature here
Thymus is where ___________ matures
Gamma interferon activates what kind of cell
macrophages are activated by what?
dermal origin of microglia
myelinate multiple axons
myelinate a single axon
schwann cells
Destroyed in MS
1. cilia
2. sweep respiratory contents and motile component of sperm
3. kartagener's dynein arm defect (resposible for retrograde transport)
1. structure,
2. fctn, and
3. one disease in which defective (specify defect also)
kinesin is involved in what?
anterograde trasport
nissl bodies are what and are found where
RER of neurons
drugs that acto on microtubules
Mebendazole/thiabenazole (antihelm)
Taxol (anti-breast cancer)
Griseofulvin (antifungal)
Colchicine (anti-gout)
frosted glass cytoplasm"
CD19 & CD20"
B cell
T cell
gamma interferon affect on macrophage
lymph drainage pwy of bladder and male glands
both drain into the internal illiacs
lymph drainage pwy of perineum
Superficial inguinal nodes -> Deep inguinal nodes -> Ext. illiacs
lymph drainage pwy of Testes
Paraaortic nodes
lymph drainage pwy of lower extremities
Superficial inguinal nodes -> Deep inguinal nodes -> Ext. illiacs
lymph drainage pwy of cervix
External and internal illiacs
lymph drainage pwy of uterus
External and internal illiacs
What nodes drain the butt, lower extremities? What else does it drain
Superficial inguinal nodes.
also drains
-ant abdominal wal
Fuel sources based on timeframe available.
-Glucose lasts 2 hrs
-Glycogen lasts 20 hours
-protein breakdown begins
-fat breakdown begins
GLUT receptor found on muscle and adipose tissue.
Bring glucose INTO the cells

inc insulin exocytosis GLUT 4 receptors putting them on membrane
4 hormones inc. serum glucose levels and onset time.
Epinephrine: 1min
Glucogon: 20min
Growth Hormone: > 24
Cortisol: 2-4 hrs
Tachycardia, and elevated BP after eating wine, beer or cheese? Name class and three drugs that can cause this reaction.
Monoamine Oxidase Inhibitors:

avoid tyramine containing foods
A carotid body tumor grows in response to what and secretes what?
It is a paraganglioma- in people at high alt, normally carotid body invloved in cardiovasc response to hypoxemia and changes in pH and PCO2
#1 Catecholamines- NE, EPI, Da
#2 peptides- Substance P, CCK, enkephalins
stab immediately left of sternal border, 4th intercostal space
right ventricle
stab immediately right of sternal border, 4th intercostal space
right atrium
tracheal deviation to the side where breath sounds are absent points to...
loss of volume (eg. atelectasis due to bronchial obstruction)
calculation for compartment volume when using inulin.
Vol. of compartment= Quant. Inulin administered /[inulin in compartment]
Mechanism of oncogenesis of HPV and Rb
inactivation of two tumor suppressor genes
mucolytic drug
N-acetylcysteine (Mucomyst) breaks disulfide linkages
characteristics that indicate intraductal papilloma vs papillary ductal carcinoma
Fibrovascular core and epithelial/myoepithelial cells
Ventilation equation
V (alveolar)= VCO2 / PCO2
Give diagnosis, Rx:
with 24h - 72h after birth infant becomes lethargic, needs stimulation to feed, vomiting, increasing lethargy, hypothermia and hyperventilation,hyperammonemia without appropriate intervention infant dies
Type I Hyperammonemia
dificiency-Carbamoylphosphate synthetase I
treament with arginine which activates N-acetylglutamate synthetase
Give diagnosis & Rx:
severe hyperammonemia, mild hyperammonemia associated with deep coma, acidosis, recurrent diarrhea, ataxia, hypoglycemia, hyperornithinemia:
N-acetylglutamate synthetase Deficiency

treatment includes administration of carbamoyl glutamate to activate CPS I
Give diagnosis & Rx & inheritance:
ammonia and amino acids elevated in serum, increased serum orotic acid due to mitochondrial carbamoylphosphate entering cytosol and being incorporated into pyrimidine nucleotides which leads to excess production and consequently excess catabolic products
Type 2 Hyperammonemia
dificiency-Ornithine transcarbamoylase

treat with high carbohydrate, low protein diet, ammonia detoxification with sodium phenylacetate or sodium benzoate
most commonly occurring UCD, only X-linked UCD,
Give diagnosis & Rx:
episodic hyperammonemia, vomiting, lethargy, ataxia, siezures, eventual coma
Classic Citrullinemia
dificiency-Argininosuccinate synthetase
treat with arginine administration to enhance citrulline excretion, also with sodium benzoate for ammonia detoxification
Give diagnosis & Rx:
episodic symptoms similar to classic citrullinemia, elevated plasma and cerebral spinal fluid argininosuccinate
Argininosuccinic aciduria
dificiency-Argininosuccinate lyase(argininosuccinase)
treat with arginine and sodium benzoate
Give diagnosis & Rx:
progressive spastic quadriplegia and mental retardation, ammonia and arginine high in cerebral spinal fluid and serum, arginine, lysine and ornithine high in urine
treatment includes diet of essential amino acids excluding arginine, low protein diet