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10 Cards in this Set
- Front
- Back
circadian rythm
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about a day
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free-running vs. entraining the rythm
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free running - clock shifts to the right
entraining the clock - locks back on to natural biological clock again *doesn't repsond to external cues |
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terminology
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free run - absense of external cues and the clock still goes
entrain - lock onto specific time -zeitgeber - cue that entrains -temp insensitivity - not dependent upon temperature |
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how do most animals best free-run?
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in total darkness
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Where is the clock?
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mammals - SCN
fish/reptiles - pineal gland insects - brain |
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SCN
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communicates via hormones, doesn't have to be connected
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Period Genes:
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per(+) -> wild-type(24 hr)
per(s) -> period short(9hr) per(Li) -> period long (29 hr) per(o) -> no period(random) |
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Explain Jet Lag
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SCN adjusts in one day but there's a seperate clock in lungs/liver/muscle that takes longer to adjust. one solution: start eating on destination time days in advance
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transcriptional clock
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genetic clock that relies on DNA transcription. Period protein shuts off period gene over a 24-hr. rythym
-doubletime breaks down per. protein -cryptochrome activated by the sun and detroys per/tim dimers |
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circannual rythm
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an annual rythym. when isolate organism, rythym drifts to the left
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