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70 Cards in this Set

  • Front
  • Back
Internal and External Oxygen Exchange
External gas exchange: Gases move between alveoli and capillary blood

Internal gas exchange: Gases move between blood and tissues
Inspiration Muscles
Inspiration: Active process-air moves into lungs
Inspiratory muscles include diaphragm and external intercostals
•Diaphragm flattens and contracts during: increases length of thorax
External intercostals relax: elevates the ribs and increases the size of thorax from the front to the back and from side to side
Expiration Muscles
Expiration: moves Carbon Dioxide outside lungs
•During expiration, thorax returns to its resting size and shape
•Elastic recoil of lung tissues aids in expiration
•Internal intercostals-contraction depresses rib cage and decreases size of thorax from front to back
•Abdominal muscles, diaphragm contracts, decreasing size of thoracic cavity from top to bottom
•Reduction in the size of the thoracic cavity increases its pressure and air leaves the lungs
Sufractant
Surfactant-reduces surface tension in alveoli to keep them from collapsing
Lobes in Lungs
Lobes-3 right, 2 left, 2 in left cause of heart
Upper Respiratory Tract vs Lower Respiratory Tract
Upper respiratory tract
1. Nose
2. Pharynx
3. Larynx

Lower respiratory tract
1. Trachea
2. Bronchial tree
3. Lungs
Portion of Brain where involuntary respiration is controlled
• Most important central regulatory centers in medulla are called respiratory control centers (inspiratory and expiratory centers). Involved in involuntary respiration.
Cyanosis
•Cyanosis: blue skin cause of lack of oxygen
Suffocation
Suffocation: No oxygen presence at all.
Hypoxemia
Hypoxemia: decreased oxygen pressure in blood, Oxygen Sat less than 90%
Hypoxia
Hypoxia: deprived of oxygen supply
Tidal Volume
Tidal volume (TV)-amount normally breathed in or out with each breath
Vital Capacity
Vital capacity (VC)-greatest amount of air that one can breathe out in one expiration
Expiratory Reserve volume
Expiratory reserve volume (ERV)-amount of air that cam be forcibly exhaled after expiring the tidal volume
Inspiratory reserve volume
Inspiratory reserve volume (IRV)-amount of air that can be forcibly inhaled after a normal inspiration
Residual Volume
Residual volume (RV)-air that remains in the lungs after the most forceful expiration
Epiglottis
A large, leaf-shaped piece of elastic cartilage. During swallowing, the pharynx and larynx rise. Elevation of the pharynx widens it to receive food and drink; elevation of the larynx causes the epiglottis to move down and form a lid over the glottis, closing it off.
Structure where gas exchange ocurrs
Alveoli
Exchange of gases in lungs
•Carbaminohemoglobin breaks down into carbon dioxide and hemoglobin
•Carbon dioxide moves out of lung capillary into alveolar air and out in expiration
•Oxygen moves from alveoli into lung capillaries
•Hemoglobin combines with oxygen, producing oxyhemoglobin
Exchange of gases in tissues
Oxyhemoglobin breaks down into oxygen and hemoglobin
Oxygen moves out of tissue capillary blood into tissue cells
Carbon dioxide moves from tissue cells into tissue capillary blood
Hemoglobin combines with carbon dioxide, forming carbaminohemoglobin
Voluntary Respiration Control
Cerebral cortex-voluntary (but limited) control of respiratory activity
APNEA
• Apnea-stopped respiration
TACHYPNEA
Tachypnea-abnormally rapid
HYPOAPNEA
Hypopnea-decreased rate and depth
HYPERAPNEA
Hyperpnea-increased rate and depth associated with increased activity. abnormally deep and rapid breathing
ORTHOPNEA
Orthopnea-labored breathing that occurs when lying flat and relieved by sitting up
HYPERCANPIA
Increased levels of carbondioxide in blood
Muscular Wave
Peristalsis is a radially symmetrical contraction of muscles which propagates in a wave down the muscular tube.Found in the contraction of smooth muscles to propel contents through the digestive tract
Enzymes in Stomach
Pepsin enzymes in charge of protein digestion, activated by hydrochloric acid
Rennin: digestion of milk protein
Hormones in Stomach
Gastrin: promotes stomach secretions and movement
Gastric inhibitor peptide: inhibits gastric juices
Enzymes in Small Intestine and what they break down
Maltase, Sucrase, Lactase: turn maltose, sucrose and lactose into glucose
Pancreatic Amylase: starches into maltose
Trypsin:Protein Digestion
Peptidases: Protein Digestion
Lipase: Fat
Nuclease: Nucleic Acid
Where does majority of digestion and absorption occurs?
Small Intestine
Chyme vs. Chyle
•Chyme: semifluid mass of partly digested food expelled by the stomach into the duodenum.

•Chyle: milky bodily fluid consisting of lymph and emulsified fats
Pancreas
Pancreatic cells produce pancreatic juices that empty into duodenum
•Pancreatic Islets of Langerhams not connected with pancreatic ducts,
• Reponsible for fat digestion (lipase),
• nucleic acids (nuclease)
• Alkaline content (bicarbonate) neutralized acidic Chyme.
Pancreatic amylase: Startch to maltose
Liver
Manufacture bile
Modify fats
Store glycogen and when needed convert to glucose
Store vitamins such as iron
Form blood plasma proteins
Destroy old RBC Synthesize urea
Detox
Hepatic Duct: bile leaves liver
Gall Bladder
• Under liver
• Function is to concentrate and store bile that is produces in liver.
• Cystic duct: duct by which bile enters and leaves the gallbladder

• Common duct: hepatic and cystic ducts together, drains into duodenum
Amylase
Salivary amylase (enzyme) breaks down starch into maltose
Hormone that Stimulates Gastric Secretion?
Gastrin: promotes stomach secretions and movement
US Dietary Guidelines
• Carbohydrates 55-50%
• Fat 30% or less
• Protein 15-20%
Heat Loss
• Radiation: loss or gain of heat from infrared radiation
• Conduction: tranfer heart from one object to another
• Convection: loss to air over body surface
• Evaporation: loss of body hear to water as is evaporated from body surface
Tough Membrane that covers testes
• Tunica Albuginea: membrane that covers also divides testis into lobules
Testosterone functions
•Made by Interstitial cells.( also known as Leydig cells)
•In seminiferous tubules in the testicle.
•LH stimulates production
•“Masculinizes” and promotes development of male accessory organs
•Aids Development of spermatozoa
Secondary sex characteristics
Female and male gonad names
Male = testes
Female= ovary
Menstrual cycle hormones
1.FSH- ripens Follicle – which makes estrogen
2.Estrogen builds endometrium, shuts FSH, Sets of LH
3.LH busts follicle releasing egg
4.Cospus Luteum forms, progesterone which inhibits LH
Stages of Reproductive Cycle
Follicular phase: Lasts from about day 4 to day 14. FSH. follicles begin to mature One follicle becomes dominant-Graafian follicle
Ovulation: About day 14. Surge of LH causes ovum to burst.Ruptured follicle transforms into corpus luteum
Luteal phase:Begins to secrete progesterone and estrogen. Cause endometrium to thicken. FSH and LH inhibited. No fertilization of ovum. Secretion of progesterone decreases. Corpus luteum declines. Endometrium degenerates→menses
Uterus linings
The myometrium makes up your uterus' second layer. Like the uterus itself, it is made up of muscles



Endometrium innermost lining of the uterus is referred to as the endometrium. It is designe to provide a home and nutrition for your baby. When you are not pregnant, your endometrial lining actually becomes your period
Sperm
• The sperm cell consists of a head, a midpiece and a tail.
• The head contains the nucleus with genetic material,
• acrosome, which contains enzymes used for penetrating the female egg. It aids in penetration of the ovum.
• The midpiece has a central filamentous core with many mitochondria spiralled around it, used for ATP production for the journey through the female cervix, uterus and uterine tubes.
• The tail or "flagellum" executes the lashing movements that propel the spermatocyte.
Progesterone
• If the egg is not fertilized, the corpus luteum stops secreting progesterone and decays (after approximately 14 days in humans). Degenerates into a corpus albicans, which is a mass of fibrous scar tissue.
• When egg is fertilized, human chorionic gonadotropin , signals the corpus luteum to continue progesterone secretion, thereby maintaining the thick lining (endometrium) of the uterus and providing an area rich in blood vessels in which the zygote(s) can develop
Follicular phase
Ovulation
Luteal phase
follicular (pre-ovulatory) phase: the ovarian follicle will undergo a series of transformations (the ovum matures), this is stimulated by the secretion of FSH.
Ovulation:a hole called the stigma will form in the follicle, and the ovum will leave the follicle through this hole. Ovulation is triggered by a spike in the amount of FSH and LH
During the luteal (post-ovulatory) phase, the ovum will travel through the fallopian tubes toward the uterus. If fertilized by a sperm, it may perform implantation there 6–12 days later. Cospus luteum will secrete estrogen and progesterone, LH and FSH go down.
Menstrual Cycle
Menses:1-5 If the blastocyst does not implant and provide feedback to the body with human cortico gonadotropin [hCG] and continued feedback through pregnancy with placental progesterone and estrogen, the endometrial lining is shed (menstrual cycle)

The proliferative phase (days 5 through 14) is the time after menstruation and before the next ovulation, when the lining of the uterus increases rapidly in thickness and the uterine glands multiply and grow.

The secretory phase (days 14 through 28) is the time after ovulation. When an egg is not fertilized, the corpus luteum gradually disappears, estrogen and progesterone (hormone) levels drop
Hormones and Stages
Menstrual and Proliferative = Follicular LH and FSH go up

Ovulation LH spikes, FSH goes down

Secretory = luteal
Estrogen and Progesterone go up, LSH and FH goes down
Chromosomes in Sex Cells Vs. Regular Cells
Regular Cells - 46
Sex Cells 23
Corpus luteum
The corpus luteum develops from an ovarian follicle during the luteal phase, following the release of a secondary oocyte from the follicle during ovulation.It releases progesterone and estrogen
Zygote
A zygote is from the union of two gametes, and constitutes the first stage in a unique organism's development. Zygotes are usually produced by a fertilization event between two haploid cells—an ovum from a female and a sperm cell from a male—which combine to form the single diploid cell.
Morula
solid mass of blastomeres resulting from a number of cleavages of a zygote, or fertilized egg. Its name derives from its resemblance to a mulberry
Blastula
The blastula (from Greek βλαστός (blastos), meaning "sprout") is an early stage of embryonic development in animals. It is also called blastosphere. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells with a large fluid filled space called the blastocoel in the animal pole of the embryo. The blastula follows the morula and precedes the gastrula
Why testes outside of body
Temperature regulation
Accessory organs female
• Oviducts (fallopian tubes)
• Uterus
• Vagina
• Bartholi Glands
• Including those in the breasts
• External genitals
Graffian Follicle
Tertiary Follicle
• Also known as a Graafian follicle
• A mature ovarian follicle in which the oocyte attains its full size and the surrounding follicular cells are permeated by one or more fluid-filled cavities
Stages of Human Embryo
Development of the Embryo
• Nervous system begins to form
• Heart and blood vessels originate
• Limb buds form
• In male, primitive testes secrete testosterone
• Human appearance

The Fetus
• month three until birth
• Organs grow and mature
• Ovaries form in female
• Most rapid growth months four to six (second trimester)
Cause of Menses?
when there is no implentation progesterone and estrogen levels decrease
Interstitial Cells
• Made by Interstitial cells.( also known as Leydig cells
• Found adjacent to the seminiferous tubules in the testicle.
• They produce testosterone in the presence of luteinizing hormone
• “Masculinizes” and promotes development of male accessory organs
• Aids Development of spermatozoa
Kidney Functions
•Excretes toxins and nitrogenous wastes
•Regulates levels of chemicals in blood
•Acid-base regulation
•Maintains water balance
•Erythropoietin (EPO): Red blood cell production regulation
•Helps regulate blood pressure
Nephron Anatomy
Renal corpuscle-Bowman’s capsule with its glomerulus
Glomerulus-network of blood capillaries between the afferent and efferent arterioles, surrounded by Bowman’s capsule
Proximal convoluted tubule: coiled part out of glomerular capsule, first segment
Loop of henle (nephron loop) : Descending limb and Ascending limb
Distal convoluted tubule-comes out of ascending limb of loop of Henle
Collecting tubule-straight extension of distal tubule, fluid drains into renal pelvis.
URINE FORMATION: FILTRATION
More blood enters glomerulous than it actually leaves so pressure is built Glomerular pressure causes water and dissolved substances to filter
Filtration: movement of water and dissolved materials through a membrane under pressure.
URINE FORMATION: REABSORPTION
As filtrate travels through nephrons tubular system, water and other substances leave the tubule and enter surrounding tissue. Movement of substances out of renal tubules into blood
Water, nutrients, and ions are reabsorbed
Most reabsorption occurs in the proximal convoluted tubule
URINE FORMATION: SECRETION
Movement of substances into urine
Happens in the distal and collecting tubules
Substances go from blood in peritubular capillaries to distal and collecting tubules
ANURIA VS POLYURIA
Anuria: no pee
Polyuria: too much pee
Retention, supression and incontinence
• Urinary retention-urine produced but not voided. Retention of urine may cause cystitis
• Urinary suppression-no urine produced but bladder is normal
• Urinay Incontinence-urine is voided involuntarily. May be caused by spinal injury or stroke
Hypoventilation vs Hyperventilation
Hypoventilation: Respiratory Acidosis

Hyperventilation: Respiratory Alkalosis